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9780121551452

Cytokines and B Lymphocytes

by
  • ISBN13:

    9780121551452

  • ISBN10:

    0121551458

  • Format: Hardcover
  • Copyright: 1990-12-01
  • Publisher: Academic Pr

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Summary

Over the past five years the major importance of cytokines in the regulation of the immune system has become established. This book is the first to review the role of these factors in the control of growth of differentiation of B lymphocytes and thus represents an up-to-date and timely overview of the B-cell response. For the immunologist, there are detailed accounts of the physio-chemical properties of the relevant cytokines and their effect on B lymphocytes from the level of receptor signalling, through ontogeny, activation and proliferation to the expression of specific immunoglobulin isotypes. For the clinician, the involvement of cytokines in disease and normal immune response is discussed.

Table of Contents

The Physiochemical Properties of B-Cell Growth and Differentiation Factors and Their Receptors
Receptor Signalling in B Lymphocytes
Role of Cytokines in the Ontogeny, Activation and Proliferation of B Lymphocytes
Cytokine Regulation of B-Cell Differentiation
Collaboration between T and B Cells
Immunoglobulin Isotype Regulation
Autocrine Aspects of the B-Lymphocyte Regulation
Cytokine Action on B Cells in Disease
B-Cell Assays for Growth and Differentiation Factors
Index
Table of Contents provided by Publisher. All Rights Reserved.

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