Cytokines and Mental Health

by Kronfol, Ziad

• ISBN13: 9781402073533
• ISBN10: 1402073534
• Format: Hardcover
• Copyright: 2003-01-01
• Publisher: Kluwer Academic Pub

Summary

Cytokines and Mental Health explores the relationship between cytokines, neural circuitry and mental health. It is interdisciplinary and "translational", bringing together information that spans the spectrum from the molecular and cellular levels to the patient and the clinic. Content includes chapters that discuss cytokine pathways in the brain, the neurochemical and neuroendocrine effects of cytokines, and the behavioral effects of cytokines including sickness behavior. These chapters in basic research are followed by a more clinical section that discusses the role of cytokines in neuropsychiatric disorders such as major depression, schizophrenia and Alzheimer's disease. The book offers different things to different people. It should be of great interest to neuroscientists and immunologists working in the field of psychoneuroimmunology. It would also greatly benefit mental health professionals including psychiatrists, psychologists and clinicians of diverse background who are interested in mind-body medicine.

Table of Contents

List of Contributors	xi
Preface	xv
Acknowledgments	xvii
Section I: Brain Effects of Cytokines: Relevance to Mental Illness
Cytokines and Cytokine Receptors: Principles of Action	1	(14)
Daniel G. Remick
Immunosensory Signaling: Role of Cytokines	15	(24)
Lisa E. Goehler
Cytokine Pathways in the Brain	39	(16)
Julio Licinio
Ma-Li Wong
Effects of Cytokines on Cerebral Neurotransmission and Potential Relationships to Function	55	(30)
Adrian J. Dunn
Cytokines and HPA Axis Regulation	85	(38)
Marni N. Silverman
Brad D. Pearce
Andrew H. Miller
Cytokines and Neuropeptides	123	(6)
Nicholas P. Plotnikoff
Robert E. Faith
Anthony J. Murgo
Section II: Behavioral Effects of Cytokines
Cytokines and Sickness Behavior	129	(18)
Robert Dantzer
Cytokines and Sleep Regulation	147	(20)
James M. Krueger
Lynn Churchill
Cytokines and Appetite	167	(44)
Wolfgang Langhans
Brian J. Hrupka
Cytokines Effects on Learning and Memory	211	(14)
John M. Petitto
Martin J. Repetto
Zhi Huang
Ray D. Beck, Jr.
David A. Hartemink
Cytokine-elicited Sensitization: Neuroendocrine, Neurotransmitter and Behavioral Responses	225	(34)
Shawn Hayley
Zul Merali
Hymie Anisman
Section III: Cytokines and Neuropsychiatric Disorders
Cytokine Regulation in Major Depression	259	(22)
Ziad Kronfol
Cytokine Regulation in Anxiety Disorders	281	(20)
Francesca Brambilla
Cytokines and Post Traumatic Stress Disorder	301	(38)
Dewleen G. Baker
Thomas D. Geracioti Jr.
John W. Kasckow
Emmanouil Zoumakis
George P. Chrousos
Cytokines and Schizophrenia	339	(30)
Thomas Pollmacher
Andreas Schuld
Dunja Hinze-Selch
Cytokine Regulation in Autism	369	(16)
Vijendra K. Singh
Cytokine Regulation in Alzheimer's Disease	385	(18)
Robert E. Mrak
Cytokines, Immunity and Disordered Sleep	403	(20)
Michael Irwin
Index	423