Dendrites

by Stuart, Greg; Spruston, Nelson; Hausser, Michael

• ISBN13: 9780198745273
• ISBN10: 0198745273
• Edition: 3rd
• Format: Hardcover
• Copyright: 2016-06-07
• Publisher: Oxford University Press

Author Biography

Greg Stuart, Head, Eccles Institute of Neuroscience, John Curtin School of Medical Research, Australian National University,Nelson Spruston, Scientific Program Director and Laboratory Head, Howard Hughes Medical Institute, Janelia Research Campus,,Michael Hausser, Professor of Neuroscience, University College London

Greg Stuart is currently Head of the Eccles Institute of Neuroscience at the Australian National University (ANU), Canberra, Australia. He did his undergraduate at Monash University (Melbourne), before doing a PhD in Neuroscience at the ANU. After his PhD he worked for 5 years at the Max Planck Institute of Medical Research in Heidelberg, Germany. During his time he developed methods for making electrical recordings from dendrites. He is considered a world expert on the physiology of neuronal dendrites and has made a number of seminal contributions to understanding how information is processed by individual nerve cells within the brain.

Nelson Spruston is currently Scientific Program Director and Laboratory Head at the HHMI Janelia Research Campus. He completed his B.Sc. at the University of British Columbia (Vancouver) and his Ph.D. at the Baylor College of Medicine (Houston). He did postdoctoral research at the Max Planck Institute of Medical Research in Heidelberg, Germany. While there, he performed the first dendritic patch-clamp recordings from hippocampal pyramidal neurons. In his own lab (first at Northwestern University and now at Janelia), Spruston studies the role of dendrites in synaptic integration and plasticity. He has also made a number of discoveries concerning the functional properties of a variety of cell types in the hippocampus.

Michael Hausser is Professor of Neuroscience at University College London and a Principal Research Fellow of the Wellcome Trust. He received his PhD from Oxford University under the supervision of Julian Jack. He subsequently worked with Bert Sakmann at the Max-Planck-Institute for Medical Research in Heidelberg and with Philippe Ascher at the Ecole Normale Superieure in Paris. He established his own laboratory at UCL in 1997 and became Professor of Neuroscience in 2001. He has made significant contributions to our understanding of the cellular basis of neural computation in the mammalian brain using a combination of experiments and theory, with a special focus on the role of dendrites. His group has helped to pioneer several new approaches for probing the function of single neurons and neural circuits in the intact brain.

Table of Contents

1. Dendrite structure, Kristen M. Harris and Josef Spacek
2. Evolution and Scaling of Dendrites, Samuel S.-H. Wang, Anthony E. Ambrosini, and Gayle M. Wittenberg
3. Dendrite Development, Hollis T. Cline
4. Molecular Determinants of Dendrite and Spine Development, Franck Polleux, Anirvan Ghosh, and Wesley B. Grueber
5. Local translation in dendrites, Irena Vlatkovic and Erin M. Schuman
6. Structure and Molecular Organization of the Postsynaptic Density, Natasha K. Hussain and Richard L. Huganir
7. Subcellular Distribution of Ligand- and Voltage-Gated Ion Channels, Zoltan Nusser
8. Neurotransmitter-gated ion channels in dendrites, R. Angus Silver, Andrew F. MacAskill, and Mark Farrant
9. Dendritic Voltage-gated Ion Channels, Jeffrey C. Magee
10. Biochemical compartmentalization in dendrites, Fritjof Helmchen and U. Valentin Nagerl
11. Spine Calcium Signaling, Adam Carter and Bernardo Sabatini
12. Principles of Dendritic Integration, Nelson Spruston, Greg Stuart, and Michael Hausser
13. Dendritic integration in vivo, Lucy Palmer, Masanori Murayama, and Matthew Larkum
14. Modeling dendrites: A personal perspective, Wilfrid Rall
15. A theoretical view of the neuron as an input-output computing device, Etay Hay, Albert Gidon, Michael London, and Idan Segev
16. Towards a simplified model of an active dendritic tree, Bartlett W. Mel
17. Modelling dendrite shape, Hermann Cuntz
18. Functional Plasticity at Dendritic Synapses, Jerome Maheux, Robert C. Froemke, and P. Jesper Sjostrom
19. Structural plasticity in dendrites and spines, Tobias Bonhoeffer and Pico Caroni
20. Molecular signaling during plasticity of dendritic spines, Ryohei Yasuda
21. Dendrites as Transmitters, Nathaniel Urban and Troy W. Margrie
22. Dendritic connectomics, Kevin M. Boergens, Manuel Berning, Moritz Helmstaedter
23. Linking Dendritic Processing to Computation and Behavior in Invertebrates, Richard B. Dewell, Fabrizio Gabbiani
24. Dendrites and Disease, Daniel Johnston, Andreas Frick, and Nicholas Poolos
25. The Future of Dendrite Research, Michael Hausser, Nelson Spruston, and Greg Stuart