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9780824701307

Design and Analysis of Animal Studies in Pharmaceutical Development

by ;
  • ISBN13:

    9780824701307

  • ISBN10:

    0824701305

  • Format: Hardcover
  • Copyright: 1998-01-15
  • Publisher: Chapman & Hall/

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Supplemental Materials

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Summary

Provides well-integrated, comprehensive coverage of all the major statistical designs & methods used for animal studies in pharmaceutical research & development. Demonstrates the correct way to interpret the results of animal studies in the risk assessment of biopharmaceutical products & clarifies detailed presentations with real-world examples.

Table of Contents

Experimental design principles for animal studies in pharmaceutical development
Interval estimation with small samples for Median Lethal Dose (LD50) or Median Effective Dose (ED50)
Principles in statistical testing in randomized toxicological studies
Subacute toxicity studies - proof of safety versus proof of hazard
Design of long-term carcinogenicity studies
Analysis of long-term carcinogenicity studies
Design of reproductive studies
Analysis of reproductive and development
Table of Contents provided by Publisher. All Rights Reserved.

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