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9780824786823

Design and Analysis of Bioavailability and Bioequivalence Studies

by ;
  • ISBN13:

    9780824786823

  • ISBN10:

    0824786823

  • Format: Hardcover
  • Copyright: 1992-06-01
  • Publisher: Marcel Dekker Inc
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Summary

"Provides a comprehensive summary of the continuously growing literature and research activities on the regulatory requirements, scientific and practical issues, and statistical methodology of the design and analysis of bioavailability and bioequivalence studies. Includes several new chapters."

Table of Contents

Designs of bioavailability studies
statistical inferences for effects from a standard 2x2 crossover design
statistical methods for average bioavailability
power and sample size determination
transformation and analysis of individual subject ratios
the assessment of inter- and intrasubject variabilities
assumptions and outliers detection
optimal crossover designs for two formulations
assessment of bioequivalence for more than two formulations
assessment of bioequivalence for
Table of Contents provided by Publisher. All Rights Reserved.

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