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9780192624949

Dialysis Amyloid

by ;
  • ISBN13:

    9780192624949

  • ISBN10:

    0192624946

  • Format: Hardcover
  • Copyright: 1996-05-02
  • Publisher: Oxford University Press

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Supplemental Materials

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Summary

Dialysis amyloidosis is a syndrome observed in dialysis patients characterized initially by joint pain, followed later by joint destruction. It is at present one of the few compliations in these patients. The factors involved in the genesis of this syndrome are not yet known with certainty and there is as yet no proven efficacious treatment otehr then renal transplantation. As a result, the interest in this topic among nephrologists remains very high. Dialysis amyloid gives general information on the pathophysiology, and the clinical aspects of all types of amyloidosis. It then goes on to discuss recently discovered B2, type of dialysis amyloidosis, from clinical and pathological features to physiological and pathophysiological aspects of thisserious complication which effects patients suffering from chronic renal failure. This book will give nephrologists and rheumatologists a clear understanding of the dialysis amyloidosis syndrome as well as making a valuable contribution to identifying strategies for treatment and prevention.

Table of Contents

General aspects of amyloidosios
Pathpophysiology of amyloidogenesis
Various clinical types of amyloidosis
Clinical characteristics of B2=microglobulin amyloidosis
Arthropathy and carpal tunnel syndrome of B2-microglobulin amyloidosis
Radiology of dialysis amyloidosis
Ultrasonography of the joints
Whole-body scintigraphy
Pathology of B2-microglobulin deposits
Composition of B2-microglobulin deposits
Description, localization, and progression of B2-microglobulin dialysis-related amyloid deposition
Physiopathology of B2-microglobulin accumulation and deposition
Characteristics of B2-microglobulin metabolism
Involvement of B2- microglobulin modified with AGEs in dialysis-related amyloidosis
Factors modifying removal and production of B2-microglobulin
Determinants of fibril precipitation and aggregation in amyloid deposits
Review of the clinical evidence on the prophylactic and therapeutic approaches to B2-microglobulin amyloidosis
Prevention and treatment of B2-microglobulin amyloidosis
Table of Contents provided by Publisher. All Rights Reserved.

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