The Digestive System; Systems of the Body Series

by Smith & Morton

• ISBN13: 9780443062452
• ISBN10: 0443062455
• Format: Paperback
• Copyright: 2001-06-18
• Publisher: Churchill Livingstone

Summary

An integrated textbook on the digestive system, covering both the basic science and major diseases of the system. Intended for medical students taking system-based, integrated courses.

Table of Contents

Overview of the Digestive System	1	(20)
Introduction	2	(1)
Case history: Ischaemic gut	2	(1)
Components of the digestive system	2	(1)
Physiological processes of the digestive system	3	(3)
Distribution of blood to the digestive organs	6	(1)
Membrane transport	7	(4)
Motility	11	(3)
Enteric nervous system	14	(2)
Control by autonomic nerves	16	(1)
Endocrine control	17	(1)
Control of blood flow	17	(1)
Control of gastrointestinal functions during a meal	18	(1)
Self-assessment case study: obesity	19	(1)
Self-assessment questions	19	(2)
The Mouth, Salivary Glands, and Oesophagus	21	(22)
Introduction	22	(1)
Case history: xerostomia	22	(1)
The mouth	22	(1)
Anatomy and histology of the tongue	23	(6)
Saliva	29	(1)
Salivary glands	30	(7)
Oesophagus	37	(4)
Self-assessment case study: denervation following wisdom tooth extraction	41	(1)
Self-assessment questions	42	(1)
The Stomach: Basic Functions	43	(14)
Introduction	44	(1)
Case history: partial gastrectomy	44	(1)
Anatomy of the stomach	44	(1)
Secretory mucosa of the stomach	45	(1)
Histology	46	(1)
Composition of gastric juice	47	(1)
Cellular mechanisms of secretion	47	(7)
Motility in the stomach	54	(2)
Self-assessment case study: excessive vomiting	56	(1)
Self-assessment questions	56	(1)
The Stomach: Control	57	(18)
Introduction	58	(1)
Case history: gastrinomas	58	(1)
Control of gastric secretion	58	(5)
Control of pepsinogen secretion	63	(1)
Control of mucus secretion	63	(1)
Trophic actions of gastrin	63	(1)
Peptic ulcer disease	63	(4)
Control of motility in the stomach	67	(2)
Control of the pyloric sphincter	69	(1)
Control of gastric function by food	69	(4)
Self-assessment case study: peptic ulcer disease	73	(1)
Self-assessment questions	74	(1)
Pancreas: Exocrine Functions	75	(14)
Introduction	76	(1)
Case history: chronic pancreatitis	76	(1)
Anatomy	77	(2)
Pancreatic juice	79	(1)
Alkaline secretion	79	(4)
Pancreatic enzymes	83	(1)
Control of secretion	84	(4)
Self-assessment case study: cystic fibrosis	88	(1)
Self-assessment questions	88	(1)
Liver and Biliary System	89	(22)
Introduction	90	(1)
Functioning of the hepatobiliary system	90	(1)
Case history: gallstone disease	90	(1)
Anatomy and morphology of the liver	91	(12)
The gallbladder	103	(6)
Self-assessment case study: paracetamol overdose	109	(1)
Self-assessment questions	109	(2)
The Small Intestine	111	(22)
Introduction	112	(1)
Case history: cholera	112	(1)
Intestinal phase of digestion	112	(1)
Anatomy and structure	113	(3)
Structure of the intestinal wall	116	(11)
Motility in the small intestine	127	(1)
Mixing and propulsion during a meal	128	(1)
Control of motility	129	(1)
Ileocaecal sphincter	130	(1)
Drugs that affect intestinal motility	131	(1)
Self-assessment case study: congenital chloridorrhoea	132	(1)
Self-assessment questions	132	(1)
Digestion and Absorption	133	(24)
Introduction	134	(1)
Case history: Crohn's disease	134	(1)
Absorption	134	(1)
Carbohydrates	135	(7)
Protein	142	(3)
Minerals and trace elements	145	(2)
Water-soluble vitamins	147	(2)
Lipids	149	(7)
Self-assessment case study: coeliac disease	156	(1)
Self-assessment questions	156	(1)
The Absorptive and Postabsorptive States	157	(18)
Introduction	158	(1)
The absorptive state	158	(1)
Case history: Diabetes-IDDM	158	(2)
Insulin	160	(9)
Postabsorptive state	169	(1)
Control of the postabsorptive state	170	(4)
Self-assessment case study: starvation	174	(1)
Self-assessment questions	174	(1)
The Colon	175	(12)
Introduction	176	(1)
Case history: Hirschsprung's disease	176	(1)
Anatomy	176	(2)
Histology	178	(1)
Appendix	179	(1)
Anal canal	179	(1)
Functions	179	(6)
Self-assessment case study: ulcerative colitis	185	(1)
Self-assessment questions	186	(1)
Gastrointestinal Pathology	187	(24)
Introduction	188	(1)
Gastrointestinal malignancy	188	(1)
Symptoms of gastrointestinal malignancy	189	(1)
Case history 11.1: colon cancer	189	(1)
Common gastrointestinal malignancies	190	(1)
Case history 11.2: colorectal cancer: treatment	191	(2)
Tumours of the pancreas	193	(1)
Case history 11.3: adenocarcinoma of the pancreas	193	(1)
Case history 11.4: adenocarcinoma of the pancreas: treatment	194	(1)
Acute abdominal pain	194	(1)
Case history 11.5: acute appendicitis	195	(1)
Case history 11.6: acute appendicitis: pathophysiology	195	(1)
Surgical resections	195	(3)
Mouth and oropharynx	198	(1)
Oesophagus	199	(1)
Stomach and duodenum	200	(1)
Hepatobiliary disease	201	(2)
Pancreas	203	(1)
Small bowel conditions	204	(3)
Large intestine	207	(1)
Ulcerative colitis	208	(3)
Answers	211	(10)
Glossary	221	(4)
Index	225	(13)
Figure acknowledgements	238