Diseases of the Breast

by Harris, Jay R.

• ISBN13: 9780781718394
• ISBN10: 0781718392
• Edition: 2nd
• Format: Hardcover
• Copyright: 2000-01-01
• Publisher: Lippincott Williams & Wilkins

Summary

Completely revised and updated, with 24 brand-new chapters, the Third Edition of this definitive reference is a must for all clinicians who treat benign or malignant breast diseases. This edition features two new sections on pathology, biological markers, and staging of breast cancer and adjuvant systemic therapy of primary breast cancer. Other new chapters cover imaging, pathogenesis of breast cancer, special therapeutic problems, and breast cancer in young women. Treatment-oriented chapters have been reorganized for greater depth of coverage. An up-to-the-minute "late-breaking" page has been added to many chapters just before publication. This edition also includes new full-color pathology illustrations.

Table of Contents

Contributing Authors	xiii
Preface	xxiii
SECTION I. BREAST ANATOMY AND DEVELOPMENT
Breast Anatomy and Development	1	(14)
Michael P. Osborne
Biochemical Control of Breast Development	15	(18)
Robert B. Dickson
Jose Russo
SECTION II. DIAGNOSIS AND MANAGEMENT OF BENIGN BREAST DISEASES
Physical Examination of the Breast	33	(4)
Monica Morrow
Management of the Palpable Breast Mass	37	(10)
Susan E. Clare
Monica Morrow
Management of Disorders of the Ductal System and Infections	47	(10)
J. Michael Dixon
Nigel J. Bundred
Management of Breast Pain	57	(6)
Ian S. Fentiman
Abnormalities of the Breast in Pregnancy and Lactation	63	(4)
Jeanne A. Petrek
Management of Gynecomastia	67	(8)
Glenn D. Braunstein
Pathology of Benign Breast Disorders	75	(20)
Stuart J. Schnitt
James L. Connolly
Techniques of Diagnosis of Palpable Breast Masses	95	(6)
Roger S. Foster, Jr.
SECTION III. BREAST IMAGING AND IMAGE-GUIDED BIOPSY TECHNIQUES
Screening for Breast Cancer	101	(22)
Robert A. Smith
Carl J. D'Orsi
Imaging Analysis of Breast Lesions	123	(26)
Daniel B. Kopans
Image-Guided Biopsy of Nonpalpable Breast Lesions	149	(16)
Luz A. Venta
Preoperative Imaging-Guided Needle Localization and Biopsy of Nonpalpable Breast Lesions	165	(10)
Daniel B. Kopans
Barbara L. Smith
SECTION IV. EPIDEMIOLOGY AND ASSESSING AND MANAGING RISK
Epidemiology and Nongenetic Causes of Breast Cancer	175	(46)
Walter C. Willett
Beverly Rockhill
Susan E. Hankinson
David J. Hunter
Graham A. Colditz
Inherited Genetic Factors	221	(16)
Angela DeMichele
Barbara L. Weber
Evaluation and Management of Women with a Strong Family History of Breast Cancer	237	(18)
Claudine J. D. Isaacs
Beth N. Peshkin
Caryn Lerman
Prophylactic Mastectomy	255	(10)
J. Dirk Iglehart
Chemoprevention	265	(16)
V. Craig Jordan
Alberto F. Costa
SECTION V. PATHOGENESIS OF BREAST CANCER
Oncogenes, Suppressor Genes, and Signal Transduction	281	(22)
Robert B. Dickson
Marc E. Lippman
Autocrine and Paracrine Growth Factors in the Normal and Neoplastic Breast	303	(16)
Robert B. Dickson
Marc E. Lippman
Animal Models	319	(16)
Robert Clarke
Michael D. Johnson
In Vitro Models	335	(20)
Robert Clarke
Fabio Leonessa
W. Nils Brunner
Erik W. Thompson
Biological Features of Human Premalignant Breast Disease	355	(12)
D. Craig Allred
Syed K. Mohsin
Control of Invasion and Metastasis	367	(10)
W. Nils Brunner
Ross W. Stephens
Keld Dano
SECTION VI. IN SITU CARCINOMA
Lobular Carcinoma in Situ	377	(6)
Monica Morrow
Stuart J. Schnitt
Ductal Carcinoma in Situ and Microinvasive Carcinoma	383	(20)
Monica Morrow
Stuart J. Schnitt
Jay R. Harris
SECTION VII. STAGING AND NATURAL HISTORY OF BREAST CANCER
Staging of Breast Cancer	403	(4)
Jay R. Harris
Natural History of Breast Cancer	407	(18)
Samuel Hellman
Jay R. Harris
SECTION VIII. PATHOLOGY AND BIOLOGICAL MARKERS OF INVASIVE BREAST CANCER
Pathology of Invasive Breast Cancer	425	(46)
Stuart J. Schnitt
Anthony J. Guidi
Estrogen and Progesterone Receptors	471	(18)
Richard M. Elledge
Suzanne A. W. Fuqua
Prognostic and Predictive Factors	489	(26)
Gary M. Clark
SECTION IX. PRIMARY TREATMENT OF INVASIVE BREAST CANCER
Local Management of Invasive Breast Cancer	515	(46)
Monica Morrow
Jay R. Harris
Breast Reconstruction	561	(16)
Neil A. Fine
Thomas A. Mustoe
Geoffery Fenner
Techniques of Surgery	577	(12)
S. Eva Singletary
Techniques of Radiation Therapy	589	(10)
Allen S. Lichter
Lori J. Pierce
Adjuvant Systemic Therapy of Primary Breast Cancer	599	(34)
C. Kent Osborne
Peter M. Ravdin
Dose-Intensive Chemotherapy	633	(12)
Nancy E. Davidson
M. John Kennedy
Deborah K. Armstrong
Treatment of Locally Advanced and Inflammatory Breast Cancer	645	(16)
Gabriel N. Hortobagyi
S. Eva Singletary
Eric A. Strom
SECTION X. SPECIAL THERAPEUTIC PROBLEMS
Male Breast Cancer	661	(8)
William J. Gradishar
Phyllodes Tumors	669	(8)
Jeanne A. Petrek
Paget's Disease	677	(6)
Carolyn M. Kaelin
Other Cancers of the Breast	683	(8)
Carl Freter
Breast Cancer Treatment in Pregnant or Postpartum Women and Subsequent Pregnancy in Breast Cancer Survivors	691	(12)
Jeanne A. Petrek
Anne Moore
Occult Primary Cancer with Axillary Metastases	703	(6)
Alain Fourquet
Anne de la Rochefordiere
Francois Campana
SECTION XI. EVALUATION AFTER PRIMARY THERAPY
Evaluation of Patients after Primary Therapy	709	(22)
Daniel F. Hayes
SECTION XII. MANAGEMENT OF RECURRENT BREAST CANCER
Local-Regional Recurrence after Mastectomy or Breast-Conserving Therapy	731	(18)
Abram Recht
Steven E. Come
Susan L. Troyan
Norman L. Sadowsky
Treatment of Metastatic Breast Cancer	749	(50)
Matthew J. Ellis
Daniel F. Hayes
Marc E. Lippman
SECTION XIII. NEW BREAST CANCER THERAPEUTIC APPROACHES
Angiogenesis as a Diagnostic and Therapeutic Target	799	(12)
Stephen B. Fox
Adrian L. Harris
Immunology and Immunotherapy	811	(14)
Martin A. Cheever
Mary L. Disis
Biological Therapy	825	(16)
Neal Rosen
Laura Sepp-Lorenzino
Marc E. Lippman
SECTION XIV. SITE-SPECIFIC THERAPY OF METASTATIC BREAST CANCER
Brain Metastases	841	(14)
Patrick Y. Wen
Timothy D. Shafman
Epidural Metastases	855	(12)
Craig D. McColl
Ronnie J. Freilich
Leptomeningeal Metastasis	867	(8)
Lisa M. DeAngelis
Lisa R. Rogers
Kathleen M. Foley
Brachial Plexopathy	875	(14)
Nathan I. Cherny
Bella Kaufman
Ocular Metastases	889	(4)
Beryl A. McCormick
David H. Abramson
Malignant Effusions	893	(8)
Lawrence N. Shulman
David J. Sugarbaker
Management of Discrete Pulmonary Nodules	901	(6)
Steven J. Mentzer
David J. Sugarbaker
Management of Discrete Liver Metastasis	907	(4)
Mark S. Talamonti
Biology of Bone Metastases	911	(10)
Gregory R. Mundy
Theresa A. Guise
Toshiyuki Yoneda
Medical Treatment of Bone Metastases	921	(10)
Richard L. Theriault
Local Treatment of Bone Metastases	931	(14)
Alan D. Aaron
Christine D. Berg
SECTION XV. BREAST CANCER IN SPECIAL POPULATIONS
Breast Cancer in Older Women	945	(10)
Gretchen G. Kimmick
Hyman B. Muss
Breast Cancer in Minority Women	955	(12)
Jon F. Kerner
Bruce J. Trock
Jeanne S. Mandelblatt
End-of-Life Considerations in Breast Cancer Patients	967	(18)
Jane M. Ingham
SECTION XVI. ISSUES IN BREAST CANCER SURVIVORSHIP
Nursing Care in Patient Management and Quality of Life	985	(16)
Karen Hassey Dow
Barbara Hansen Kalinowski
Rehabilitation Management: Restoring Fitness and Return to Functional Activity	1001	(8)
Lynn H. Gerber
Elizabeth M. Augustine
Psychosocial Issues and Interventions	1009	(24)
Julia H. Rowland
Mary Jane Massie
Lymphedema	1033	(8)
Jeanne A. Petrek
Robert Lerner
Managing Menopausal Problems	1041	(10)
Melody A. Cobleigh
Reproductive Issues	1051	(10)
Harold J. Burstein
Eric P. Winer
SECTION XVII. MEDICOLEGAL CONSIDERATIONS
Medicolegal Aspects of Breast Cancer Evaluation and Treatment	1061	(8)
R. James Brenner
SECTION XVIII. BASIC TOOLS FOR ADVANCING KNOWLEDGE IN BREAST CANCER
Techniques in Molecular Biology	1069	(16)
David Malkin
Hilmi Ozcelik
Techniques in Breast Cancer Clinical Trials	1085	(18)
Rebecca S. Gelman
Techniques in the Assessment of Quality of Life	1103	(6)
May Lin Tao
Patricia A. Ganz
Techniques Used in the Assessment of Cost-Effectiveness	1109	(10)
James A. Hayman
Jane C. Weeks
Index	1119