Disorders of Voluntary Muscle

by Edited by George Karpati , David Hilton-Jones , Robert C. Griggs , Foreword by Lord Walton of Detchant

• ISBN13: 9780521650625
• ISBN10: 0521650623
• Edition: 7th
• Format: Hardcover
• Copyright: 2001-09-03
• Publisher: Cambridge University Press

Summary

The seventh edition of Disorders of Voluntary Muscle has been rewritten and redesigned with the needs of the clinician and clinical scientist in mind. It contains up-to-date information on the etiology and pathogenesis of diseases of skeletal muscles, including the mitochondrial myopathies, ion channel disorders, muscular dystrophies and dysimmune myopathies. It covers the many recently identified diseases of muscle, and emphasises the progress that has been made in diagnosis and treatment. As background to the clinical coverage, the new edition also has chapters summarizing advances in molecular and developmental biology, immunopathology, mitochondrial biology, ion-channel dynamics, cell membrane and signal transduction science, and imaging technology. Combining essential new knowledge with the fundamentals of history taking and clinical examination, this extensively illustrated book will continue to be the mainstay for practising physicians and biomedical scientists concerned with muscle disease.

Table of Contents

Foreword Lord Walton of Detchant

Preface

Part I. Scientific Basis of Muscle Disease: 1. The structure and function of motor units Robert E. Burke

2. Developmental biology of skeletal muscle Jeffrey B. Miller

3. The molecular and cellular biology of muscle Susan C. Brown, Frank S. Walsh and George Dickson

4. The molecular basis of muscle disease Louise V. B. Anderson

5. Mitochondria Eric A. Shoubridge

6. The sarcotubular system Kimby N. Barton and David H. MacLennan

7. The extracellular matrix of skeletal muscle Paul C. Holland and Salvatore Carbonetto

8. Aspects of skeletal muscle biochemistry in health and disease John M. Land

9. The neuromuscular junction and neuromuscular transmission Angela Vincent

10. The pathophysiology of excitation in skeletal muscle Robert L. Barchi

11. Animal models of human muscle disease Barry J. Cooper

Part II. Methods of Investigation of Muscle Disease: 12. Applied physiology of muscle Eric L. Logigian and Richard L. Barbano

13. Histochemistry and immunocytochemistry of muscle in health and disease Caroline A. Sewry and Victor Dubowitz

14. Muscle pathology on semithin resin sections Stirling Carpenter

15. Electron microscopy in the study of normal and diseased muscle Stirling Carpenter

16. Magnetic resonance imaging and spectroscopy of muscle D. J. Taylor, J. L. Fleckenstein and R. Lodi

Part III. Description of Muscle Disease: 17. The examination and investigation of the patient with muscle disease David Hilton-Jones and John T. Kissel

18. The classification of muscle diseases Michael H. Brooke

19. Dystrophinopathies Eric P. Hoffman

20. Limb-girdle muscular dystrophies Jean-Claude Kaplan, Jacques S. Beckmann and Michel Fardeau

21. Facioscapulohumeral dystrophy Rabi Tawil and Robert C. Griggs

22. Distal myopathies Richard J. Barohn and Robert C. Griggs

23. Emery-Dreifuss dystrophy Kiichi Arahata

24. Oculopharyngeal muscular dystrophy Bernard Brais

25. Congenital muscular dystrophies Thomas Voit

26. Congenital myopathies Hans H. Goebel

27. Myotonic dystrophy Peter S. Harper

28. The metabolic myopathies Richard T. Moxley III, Patrick Chinnery and Douglas Turnbull

29. Oxidative phosphorylation diseases of muscle John M. Shoffner and Eric Shoubridge

30. Ion channel disorders of muscle Louis J. Ptá

cek and Saï

d Bendahhou

31. Inflammatory myopathies Marinos C. Dalakos and George Karpati

32. Myasthenia gravis and myasthenic syndromes: autoimmune and genetic disorders John Newsom-Davis and David Beeson

33. Toxic and iatrogenic myopathies and neuromuscular transmission disorders Zohar Argov, Henry J. Kaminski, Ali Al-Mudallal and Robert L. Ruff

34. Painful muscle syndromes Russell Lane

Part IV. The Principles of Management of Muscle Disease: 35. Genetic counselling in muscle disease K. Bushby

36. The principles of treatment, prevention and rehabilitation: perspectives on future treatment Giovanni Meola, George Karpati and R. C. Griggs

Index.