Drug Delivery to the Oral Cavity: Molecules to Market

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  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2005-02-28
  • Publisher: CRC Press

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With contributions from recognized authorities in industry, academia, and government. Drug Delivery to the Oral Cavity: Molecules to Market provides information unavailable elsewhere in the literature on recently commercialized and emerging intraoral drug delivery products. It presents the state-of-the-art in the testing, formulation, and clinical evaluation of intraoral drug delivery products and summarizes intraoral dosage forms in various stages of research, as well as products currently on the market. Emphasizing the impact of intraoral drug delivery and its advantages over conventional oral dosage forms, this handbook covers the latest research concerning drug delivery to the oral cavity.

Table of Contents

Intraoral delivery systems : an overview, current status, and future trendsp. 1
Preclinical assessment of oral mucosal drug delivery systemsp. 41
Modulation of oral transmucosal permeability : permeation enhancersp. 67
Oral transmucosal delivery of protein and peptide therapeuticsp. 89
Sublingual transmucosal delivery of organic nitrates : treatment of angina pectorisp. 111
Oral transmucosal delivery of melatoninp. 125
Oral transmucosal delivery of nicotine : smoking cessation therapyp. 149
Oral transmucosal powder injectionp. 191
Drug delivery systems for the treatment of periodontal and dental diseasesp. 211
Oral transmucosal systems for local anesthetics : dental and oral surgical premedicationp. 233
Quick-dispersing oral drug delivery systemsp. 261
Quick-dissolving intraoral tabletsp. 291
Process development and scale-up of oral fast-dissolving tabletsp. 311
Quick-dissolving oral dosage forms : scientific and regulatory considerations from a clinical pharmacology and biopharmaceutics perspectivep. 337
Quick reference guide to worldwide companies developing intraoral drug delivery technologies and productsp. 357
Quick reference guide to books and market research reports on companies developing intraoral drug delivery technologies and productsp. 385
Glossary : abbreviations and definitionsp. 389
Table of Contents provided by Blackwell. All Rights Reserved.

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