Drug Interactions in Infectious Diseases

by Piscitelli, Stephen C.

• ISBN13: 9781588294555
• ISBN10: 1588294552
• Edition: 2nd
• Format: Hardcover
• Copyright: 2005-08-01
• Publisher: Springer Verlag

Summary

This second edition of the highly praised Drug Interaction in Infectious Diseases includes all the major recent advances in the understanding of drug interactions, with emphasis on the many new drugs approved since the first edition. The treatment of the mechanisms of drug interaction has increased to fill two chapters, allowing a more detailed description of absorption, metabolism, and excretion, as well as describing the growing knowledge of transport proteins. Recent reports of drug interactions, new case studies, and a new chapter outlining the regulatory perspective on interaction studies during drug development have been added. The information contained in the book ranges from detailed tables of specific drug-drug interactions to in-depth discussions of interaction mechanisms and research issues.

Table of Contents

Foreword	v
Preface	vii
Contributors	ix
Introduction to Drug Interactions	1	(12)
Keith Gallicano
George Drusano
Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretion	13	(28)
Angela D. M. Kashuba
Joseph S. Bertino, Jr.
Mechanisms of Drug Interactions II: Transport Proteins	41	(42)
Scott R. Penzak
Drug Interactions: Regulatory Perspective	83	(18)
Kellie Schoolar Reynolds
Drug Interactions With Antiretrovirals for HIV Infection	101	(36)
Kimberly A. Struble
Stephen C. Piscitelli
Drugs for HIV-Related Opportunistic Infections	137	(54)
Alice Tseng
Drugs for Tuberculosis	191	(24)
Rocsanna Namdar
Steven C. Ebert
Charles A. Peloquin
Quinolones	215	(40)
David R. P. Guay
β-Lactam Antibiotics	255	(34)
Melinda M. Neuhauser
Larry H. Danziger
Antifungal Agents	289	(50)
Paul O. Gubbins
Scott A. McConnell
Jarrett R. Amsden
Miscellaneous Antibiotics	339	(44)
Gregory M. Susla
Drug-Food Interactions	383	(48)
Kelly A. Harris
Kevin W. Garey
Keith A. Rodvold
Drug-Cytokine Interactions	431	(32)
Curtis E. Haas
Jamie L. Nelsen
Circumventing Drug Interactions	463	(20)
Douglas N. Fish
Design and Data Analysis of Drug Interaction Studies	483	(24)
David E. Nix
Keith Gallicano
Index	507