Drugs & Behavior

by McKim, William A., Ph.D.; Hancock, Stephanie, Ph.D

• ISBN13: 9780205242658
• ISBN10: 0205242650
• Edition: 7th
• Format: Paperback
• Copyright: 2012-07-08
• Publisher: Pearson

Summary

An up-to-date overview of behavioral pharmacology. Drugs & Behaviorstarts with descriptions of basic pharmacological concepts of drug administration and pharmacokinetics, research methodology including clinical trials, tolerance and withdrawal, drug conditioning, addiction processes, and the neuroscience of drug action. Each chapter applies these concepts to different classes of recreational and therapeutic drugs. Each chapter also includes a section on the history of the drug class being described to place the drugs in their historical and social context. The text is written to be understandable to students without a background in pharmacology, neuroscience, or psychology. Learning Goals Upon completing this book, readers should be able to: Understand the behaviors of people who use drugs as medicine and for recreation Understand new trends and developments in pharmacology Identify the subjective, behavioral, and neurological differences between the use of both classes of drug Note:MySearchLab does not come automatically packaged with this text. To purchase MySearchLab, please visit:www.mysearchlab.comor you can purchase a ValuePack of the text + MySearchLab (at no additional cost): ValuePack ISBN-10: 0205900909.

Table of Contents

Found in this Section:

1. Brief Table of Contents

2. Full Table of Contents

 

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1. BRIEF TABLE OF CONTENTS

 

Chapter 1 Some Basic Pharmacology

Chapter 2 Behavioral Analysis of Drug Effects  

Chapter 3 How We Adapt To Drugs – Tolerance, Sensitization, and Expectation

Chapter 4 Neurophysiology, Neurotransmitters, and the Nervous System

Chapter 5 Substance Use and Addictive Disorders 

Chapter 6 Alcohol

Chapter 7 Anxiolytics and sedative-hypnotics  

Chapter 8 Tobacco and Nicotine

Chapter 9 Caffeine and the Methylxanthines 

Chapter 10 Psychomotor Stimulants 

Chapter 11 Opioids

Chapter 12 Antipsychotic Drugs

Chapter 13 Antidepressants  

Chapter 14 Cannabis

Chapter 15 Hallucinogens, Phantasticants, and Club Drugs

 

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2. FULL TABLE OF CONTENTS

 

Chapter 1:  Some Basic Pharmacology

What Is A Drug?

Names of Drugs

Describing Dosages

Potency and Effectiveness

Primary Effects And Side Effects

Drug Interactions

Pharmacokinetics

Inhalation

Oral Administration

Transdermal Administration

Distribution of Drugs

Elimination

Combining Absorption and Excretion Functions

The Therapeutic Window

 

Chapter 2:  Behavioral Analysis of Drug Effects

History of Behavioral Pharmacology

Research Design

Measuring Unconditioned Behavior of Nonhumans

Measuring Conditioned Behavior of Nonhumans

Measuring Behavior of Humans

Development and Testing of Psychotherapeutic Drugs

 

Chapter 3: How We Adapt To Drugs – Tolerance, Sensitization, and Expectation

Tolerance

Withdrawal

Conditioning of Drug Effects

Sensitization

Expectancy and Context

 

Chapter 4: Neurophysiology, Neurotransmitters, and the Nervous System

The Neuron

The Synapse

The Nervous System

Development Of The Nervous System and Potential For Disruption

Neurotransmitters

Brain Imaging of Drug Effects

 

Chapter 5: Substance Use and Addictive Disorders

Defining Addiction

History of Research on Drug Use and Addiction

Addiction as Physical Dependence

Modern Behavioral Explanations of Drug Use

The Neuroanatomy of Motivation and Reinforcement

What Happens During Addiction?

Incentive Sensitization Theory

Hedonic Dysregulation and Adaptation

Disruption of Brain Control Circuits

Treating Drug Addiction

 

Chapter 6:  Alcohol

Source of Alcohol

Origin and History

Measuring Alcohol Levels in The Body

Route of Administration and Pharmacokinetics

Absorption

Distribution

Elimination

Neuropharmacology

Alcohol Antagonists

Effects of Alcohol

Effects on Human Behavior and Performance

Effects on the Behavior of Nonhumans

Discriminative Stimulus Properties

Tolerance

Withdrawal

Self-Administration in Nonhumans

Self-Administration in Humans

Alcoholism

Harmful Effects of an Acute Administration

Harmful Effects of Chronic Consumption

Benefits of Alcohol Consumption

Treatments

 

Chapter 7: Anxiolytics and sedative-hypnotics

The Nature and Neurophysiology of Anxiety

Introduction to Anxiolytics and Sedative-Hypnotics

History of Anxiolytic and Sedative-Hypnotic Drug Development

Neurophysiology

Route of Administration and Absorption

Distribution and Excretion

Effects on the Body

Effects on Behavior and Performance of Humans

Effects on Performance

Effects on the Behavior of Nonhumans

Discriminative Stimulus Properties

Tolerance

Withdrawal

Self-Administration in Humans

Self-Administration in Nonhumans

Harmful Effects

Treatment

 

Chapter 8: Tobacco and Nicotine

Preparations

Route of Administration

Distribution

Excretion

Neurophysiology

Effects of Nicotine

Effects on the Behavior and Performance of Humans

Effects on the Behavior of Nonhumans

Drug State Discrimination

Self-Administration in Humans

Harmful Effects

Treatments                  

 

Chapter 9: Caffeine and the Methylxanthines

Sources of Methylxanthines

History of Methylxanthine Use

Extent of Methylxanthine Use

Route of Administration

Absorption

Distribution

Excretion

Neurophysiology

Effects of Caffeine and the Methylxanthines

Discriminative Stimulus Properties

Withdrawal

Self-Administration in Nonhumans

Self-Administration in Humans

Harmful Effects

Beneficial Effects

Epilogue

 

Chapter 10: Psychomotor Stimulants

Sources

History

Routes of Administration and Absorption

Distribution

Excretion

Neurophysiology

Effects of Psychomotor Stimulants

Effects on the Behavior and Performance Of Humans

Effects on the Behavior of Nonhumans

Dissociation and Drug State Discrimination

Tolerance

Withdrawal

Self-Administration in Humans

Harmful Effects

Treatment

 

Chapter 11: Opioids

Origins and Sources of Opioids

History

Routes of Administration

Distribution

Excretion

Neurophysiology

Effects of Opioids

Effects on Human Behavior and Performance

Effects on the Behavior of Nonhumans

Drug State Discrimination

Tolerance

Self-Administration in Humans

Self-Administration in Nonhumans

Harmful Effects

Pharmacological Treatment of Opioid Addiction

 

Chapter 12: Antipsychotic Drugs

The Nature of Schizophrenia

Theories of Schizophrenia 

Discovery of Antipsychotic Medications

Comparing Typical and Atypical Antipsychotics

Routes of Administration

Absorption and Distribution

Excretion

Effects of Antipsychotics

Effects on the Behavior and Performance of Humans

Effects on the Behavior of Nonhumans

Drug State Discrimination and Dissociation

Tolerance

Withdrawal

Self-Administration in Humans and Nonhumans

Harmful Effects

Other Therapeutic Effects of Antipsychotic Drugs

 

Chapter 13: Antidepressants

The Nature of Depression

Theories of Depression

History of Antidepressant Medications

Neurophysiology

Absorption

Distribution

Excretion

Effects of Antidepressants

Effects on the Behavior and Performance of Humans

Effects on the Behavior of Nonhumans

Discriminative Stimulus Properties

Tolerance

Withdrawal

Self-Administration in Humans and Nonhumans

Harmful Effects

Other Treatments for Depression

 

Chapter 14: Cannabis

History

The Cannabinoids

Absorption

Distribution

Excretion

Neuropharmacology

Effects of Cannabis

Effects on Behavior and Performance Of Humans

Effects on the Behavior Of Nonhumans

Dissociation

Drug State Discrimination

Tolerance

Withdrawal

Self-Administration in Humans and Nonhumans

Epidemiology

Harmful Effects

 

Chapter 15: Hallucinogens, Phantasticants, and Club Drugs

LSD and the Monoamine-Like Drugs

Ecstasy and Synthetic Mescaline-Like Drugs

Salvia

Dissociative Anesthetics: Phencyclidine and Ketamine

Dextromethorphan

GHB

Mephedrone