Drugs and Pregnancy

by Gilstrap, Larry C.; Little, B. B.

• ISBN13: 9780412122019
• ISBN10: 0412122014
• Edition: 2nd
• Format: Hardcover
• Copyright: 1999-01-28
• Publisher: Hodder Education Publishers

Summary

This volume provides information for obstetricians and fetal-maternal medicine specialists on the clinical evaluation of the pregnant woman inadvertently exposed to medications. Clear advice on the formulation of safe medication regimes for the treatment of pregnant women with specificconditions requiring intervention is also provided. Although the pregnant woman has the full enzyme complement for metabolizing drugs, most systems have lower activity during pregnancy. Hence, the responses of adults, fetuses, embryos, and pregnant women to drugs differ. This is an overall andsignificant updating of the successful first edition published in 1992. The authors have added a key chapter on tobacco use during pregnancy and included a variety of photos and line drawings.

Table of Contents

Preface	xi	(2)
Contributors	xiii
Part I Introduction: General Principles of Human Teratology, Clinical Evaluation of the Use of Drugs in Pregnancy, Patient Counseling	3	(42)
Chapter 1 Introduction to Drugs in Pregnancy	3	(4)
Bertis B. Little
Larry C. Gilstrap III
Chapter 2 Human Teratology Principles	7	(18)
Bertis B. Little
Larry C. Gilstrap III
Chapter 3 Counseling and Evaluation of the Drug-Exposed Pregnant Patient	25	(8)
Bertis B. Little
Larry C. Gilstrap III
Chapter 4 Legal Considerations of Drugs in Pregnancy	33	(12)
Robert L. Brent
Part II Medication Use during Pregnancy	45	(324)
Chapter 5 Antimicrobial Agents during Pregnancy	45	(32)
Larry C. Gilstrap III
Bertis B. Little
Chapter 6 Cardiovascular Drugs during Pregnancy	77	(26)
Larry C. Gilstrap III
Bertis B. Little
Chapter 7 Antiasthma Agents during Pregnancy	103	(18)
Susan M. Ramin
Bertis B. Little
Larry C. Gilstrap III
Chapter 8 Analgesics during Pregnancy	121	(16)
Larry C. Gilstrap III
Bertis B. Little
Chapter 9 Anticonvulsant Drugs during Pregnancy	137	(12)
Deborah T. Combs Cantrell
Larry C. Gilstrap III
Bertis B. Little
Chapter 10 Anticoagulants, Thrombolytics and Hemostatics during Pregnancy	149	(12)
Larry C. Gilstrap III
Bertis B. Little
Chapter 11 Psychotropics in Pregnancy	161	(30)
Susan M. Ramin
Larry C. Gilstrap III
Bertis B. Little
Chapter 12 Antineoplastic Drugs during Pregnancy	191	(26)
Larry C. Gilstrap III
Bertis B. Little
David Scott Miller
Chapter 13 Immunosuppressants during Pregnancy	217	(12)
Larry C. Gilstrap III
Bertis B. Little
Chapter 14 Endocrine Disorders during Pregnancy: Embryotoxic Versus Fetal Effects	229	(28)
William H. Kutteh
Bertis B. Little
Chapter 15 Contraception, Treatment for Infertility and General Hormonal Therapy during Pregnancy	257	(16)
William H. Kutteh
Bertis B. Little
Chapter 16 Use of Dermatologics during Pregnancy	273	(14)
Larry C. Gilstrap III
Bertis B. Little
Chapter 17 Antihistamines, Decongestants and Expectorants during Pregnancy	287	(8)
Bertis B. Little
Larry C. Gilstrap III
Chapter 18 Gastrointestinal Medications during Pregnancy	295	(16)
Larry C. Gilstrap III
Bertis B. Little
Chapter 19 Tocolytics	311	(10)
Susan M. Cox
Bertis B. Little
Larry C. Gilstrap III
Chapter 20 Nutritional and Dietary Supplementation during Pregnancy	321	(12)
Bertis B. Little
Larry C. Gilstrap III
Chapter 21 Anesthetic Agents and Surgery during Pregnancy	333	(14)
Larry C. Gilstrap III
Bertis B. Little
Chapter 22 Use of Diagnostic Agents during Pregnancy	347	(8)
Diane M. Twickler
Larry C. Gilstrap III
Bertis B. Little
Chapter 23 Occupational Exposures during Pregnancy	355	(14)
Bertis B. Little
Larry C. Gilstrap III
Mark A. Peterman
Part III Substance Abuse during Pregnancy	369	(116)
Chapter 24 Introduction to Substance Abuse during Pregnancy	369	(8)
Bertis B. Little
Toosje T. VanBeveren
Larry C. Gilstrap III
Chapter 25 Drug Overdoses during Pregnancy	377	(18)
Bertis B. Little
Larry C. Gilstrap III
Toosje T. VanBeveren
Chapter 26 Alcohol Use during Pregnancy and Maternal Alcoholism	395	(10)
Bertis B. Little
Toosje T. VanBeveren
Larry C. Gilstrap III
Chapter 27 Amphetamine Abuse during Pregnancy	405	(8)
Bertis B. Little
Toosje T. VanBeveren
Larry C. Gilstrap III
Chapter 28 Cannabinoid Use during Pregnancy	413	(6)
Bertis B. Little
Toosje T. VanBeveren
Larry C. Gilstrap III
Chapter 29 Cocaine Abuse during Pregnancy	419	(26)
Bertis B. Little
Toosje T. VanBeveren
Larry C. Gilstrap III
Chapter 30 Use of Hallucinogens during Pregnancy	445	(4)
Bertis B. Little
Toosje T. VanBeveren
Larry C. Gilstrap III
Chapter 31 Opiate Abuse during Pregnancy	449	(8)
Bertis B. Little
Larry C. Gilstrap III
Toosje T. VanBeveren
Chapter 32 Inhalant (Organic Solvent) Abuse during Pregnancy	457	(6)
Bertis B. Little
Toosje T. VanBeveren
Larry C. Gilstrap III
Chapter 33 Tobacco Use in Pregnancy	463	(12)
Bertis B. Little
Larry C. Gilstrap III
Chapter 34 Other Substances Abused during Pregnancy	475	(10)
Bertis B. Little
Toosje T. VanBeveren
Larry C. Gilstrap III
Index	485	(22)
Drug-Names Index	507