Tightly organized into a super-condensed outline bulleted format, this completely revised and updated Second Edition of Dx/Rx: Leukemia provides precise, up-to-date information for diagnosis and surgical, radiotherapeutic and chemotherapeutic treatment of Leukemia. Throughout the book, tables and figures summarize important clinical data and current professional society recommendations, while salient references direct readers to additional information. Current, quick, and concise, for instant access on the ward or in the clinic!

Editor's Preface	p. ix
Preface	p. xi
Acknowledgments	p. xiii
Notice	p. xv
General Features of Acute Leukemias	p. 1
Introduction	p. 1
Definition of Acute Leukemias	p. 1
Clinical Features of Acute Leukemias	p. 2
Diagnosis Evaluation	p. 3
Principles of Chemotherapy Treatment	p. 6
Principles of Hematopoietic Cell Transplantation (HCT)	p. 10
References	p. 11
Acute Myeloid Leukemia	p. 15
Epidemiology	p. 15
Classification	p. 16
Pathology	p. 16
Prognosis	p. 28
Treatment of AML	p. 29
Treatment of APL	p. 36
References	p. 41
Myelodysplastic Syndromes	p. 47
Definition	p. 47
Epidemiology	p. 47
Classification	p. 48
Pathogenesis	p. 48
Pathology	p. 48
Clinical Features	p. 53
Course and Prognosis	p. 54
Differential Diagnosis	p. 57
Diagnostic Evaluation	p. 57
Treatment	p. 57
References	p. 63
Acute Lymphoblastic Leukemia	p. 67
Epidemiology	p. 67
Definition and Classification	p. 67
Pathology	p. 69
Prognosis	p. 74
Treatment of Precursor ALL	p. 74
References	p. 90
Chronic Lymphocytic Leukemia	p. 95
Definition	p. 95
Epidemiology	p. 95
Pathology	p. 95
Clinical Features	p. 99
Diagnostic Evaluation	p. 100
Staging	p. 100
Prognosis	p. 100
Treatment	p. 101
Other Considerations in the Management of Patients with CLL	p. 108
References	p. 109
Myeloproliferative Disorders	p. 113
Introduction	p. 113
CML	p. 113
Polycythemia Vera	p. 128
Essential Thrombocythemia	p. 135
Primary Myelofibrosis	p. 139
Others	p. 145
Mastocytosis	p. 149
References	p. 155
Uncommon Leukemias	p. 163
Prolymphocytic Leukemia (PLL)	p. 163
Large Granular Lymphocyte (LGL) Leukemia	p. 165
Hairy Cell Leukemia	p. 167
Adult T-Cell Leukemia/Lymphoma (ATLL)	p. 172
References	p. 176
Aplastic Anemia	p. 181
Definition	p. 181
Epidemiology	p. 181
Causes	p. 181
Pathology	p. 181
Pathophysiology	p. 182
Clinical Features	p. 182
Classification of the International Aplastic Anemia Study Group	p. 183
Diagnostic Evaluation in Patients with Pancytopenia	p. 183
Treatment	p. 185
Prognosis	p. 190
Paroxysmal Nocturnal Hemoglobinuria (PNH)	p. 191
References	p. 194
Plasma Cell Neoplasms	p. 197
WHO Classification of Plasma Cell Neoplasms	p. 197
Monoclonal Gammopathy of Undetermined Significance (MGUS)	p. 197
Plasma Cell Myeloma (Multiple Myeloma) and Variants	p. 199
Plasmacytoma	p. 217
Monoclonal Immunoglobulin Deposition Diseases	p. 217
Osteosclerotic Myeloma (POEMS Syndrome)	p. 220
Heavy Chain Diseases	p. 220
References	p. 221
Index	p. 227
Table of Contents provided by Ingram. All Rights Reserved.

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