Dynamic Contrast-Enhanced Magnetic Resonance Imaging in Oncology

by Jackson, A.; Buckley, D. L.; Parker, Gwengale J.

• ISBN13: 9783540423225
• ISBN10: 3540423222
• Format: Hardcover
• Copyright: 2005-01-30
• Publisher: Springer Verlag

Summary

Dynamic contrast-enhanced MRI is now established as the methodology of choice for the assessment of tumor microcirculation in vivo. This is assisting clinical practitioners in the management of patients with solid tumors and is finding prominence in the assessment of tumor treatments, including anti-angiogenics, chemotherapy, and radiotherapy. In this book, targeted at both clinical practitioners and basic scientists, the principles of the methods, their practical implementation, and their application to specific tumor types are discussed by the leading authorities in the field today. The book will serve as an invaluable single-volume reference covering all the latest developments in contrast-enhanced oncological MRI.

Author Biography

Alan Jackson, Professor of Neuroradiology at the University of Manchester, UK.David Buckley, Lecturer in Magnetic Resonance Imaging at the University of Manchester, UK. Previous positions at the Universities of Florida, USA and Hull, UK.Geoff Parker, Lecturer in Imaging Science at the University of Manchester, UK. Previous positions at the Institute of Neurology, London, UK and the Institute of Cancer Research, London, UK.

Table of Contents

Principles of Dynamic Contrast-Enhanced MRI	1	(92)
An Introduction to Dynamic Contrast-Enhanced MRI in Oncology	3	(20)
Ingrid S. Gribbestad
Kjell I. Gjesdal
Gunnar Nilsen
Steinar Lundgren
Mari H. B. Hjelstuen
Alan Jackson
Contrast Agents for Magnetic Resonance Imaging	23	(16)
Timothy P. L. Roberts
Michael D. Noseworthy
The Role of Blood Pool Contrast Media in the Study of Tumor Pathophysiology	39	(14)
Laure S. Fournier
Robert C. Brasch
Quantification of Dynamic Susceptibility Contrast T2* MRI in Oncology	53	(16)
Fernando Calamante
Measuring Contrast Agent Concentration in T1-Weighted Dynamic Contrast-Enhanced MRI	69	(12)
David L. Buckley
Geoffrey J. M. Parker
Tracer Kinetic Modelling for T1-Weighted DCE-MRI	81	(12)
Geoffrey J. M. Parker
David L. Buckley
Imaging Techniques	93	(22)
Imaging Techniques for Dynamic Susceptibility Contrast-Enhanced MRI	95	(14)
Michael Pedersen
Peter van Gelderen
Chrit T. W. Moonen
Consensus Recommendations for Aquisition of Dynamic Contrast-Enhanced MRI Data in Oncology	109	(6)
Jeffrey L. Evelhoch
Clinical Applications	115	(148)
Dynamic Contrast-Enhanced MRI in Cerebral Tumours	117	(28)
Xiao Ping Zhu
Kah Loh Li
Alan Jackson
Dynamic Magnetic Resonance Imaging in Breast Tumours	145	(30)
Mei-Lin W. Ah-See
Anwar R. Padhani
Dynamic Contrast Enhancemed MR Imaging for Predicting Tumor Control in Patients with Cervical Cancer	175	(16)
Joseph F. Montebello
Nina A. Mayr
William T. C. Yuh
D. Scott McMeekin
Dee H. Wu
Michael W. Knopp
Dynamic Contrast-Enhanced MRI of Prostate Cancer	191	(24)
Anwar R. Padhani
Dynamic Contrast-Enhanced MR Imaging in Musculoskeletal Tumors	215	(24)
June S. Taylor
Wilburn E. Reddick
Dynamic Contrast-Enhanced MRI in the Liver	239	(24)
Alan Jackson
David A. Nicholson
Applications	263	(36)
Use of Dynamic Contrast-Enhanced MRI in Multi-Centre Trials with Particular Reference to Breast Cancer Screening in Women at Genetic Risk	265	(16)
Martin O. Leach
Applications of Dynamic Contrast-Enhanced MRI in Oncology Drug Development	281	(18)
Gordon C. Jayson
John C. Waterton
Subject Index	299	(10)
List of Contributors	309