Early Clinical Intervention and Prevention in Schizophrenia

by Stone, William S.; Faraone, Stephen V.; Tsuang, Ming T.

• ISBN13: 9781588290014
• ISBN10: 1588290018
• Edition: CD
• Format: Hardcover
• Copyright: 2004-02-01
• Publisher: Humana Pr Inc

Summary

Leading and internationally recognized researchers review what is known about the liability to schizophrenia, how it progresses, what it looks like clinically-with an emphasis on a specific (proposed) syndrome of liability (schizotaxia)-and how best it might be treated now and in the near future. The authors summarize the latest findings on the genetic, early environmental, and neurodevelopmental origins of schizophrenia.

Table of Contents

Preface	v
Contributors	xi
Value-Added eBook/PDA	xiv
Part I. The Etiology and Genetics of Schizophrenia
The Genetic Basis of Schizophrenia	3	(20)
Stephen V. Faraone
Stephen J. Glatt
Levi Taylor
Early Environmental Determinants of Schizophrenia	23	(20)
Jason Schiffman
John Carter
Ricardo A. Machon
Sarnoff Mednick
Obstetric Risk Factors for Schizophrenia and Their Relationship to Genetic Predisposition: Following Ariadne's Double-Stranded Thread Through Early Development	43	(32)
Stefano Marenco
Daniel R. Weinberger
Part II. The Vulnerability to Schizophrenia
The Nature of the Prodrome in Schizophrenia	75	(18)
Jaak Rakfeldt
Thomas H. McGlashan
The Nature of Schizotaxia	93	(22)
Stephen V. Faraone
Ming T. Tsuang
Sarah I. Tarbox
A Neuropsychological Perspective on Vulnerability to Schizophrenia: Lessons From High-Risk Studies	115	(18)
Allan F. Mirsky
Connie C. Duncan
Neurocognitive Deficits in the Biological Relatives of Individuals With Schizophrenia	133	(26)
William S. Kremen
Anne L. Hoff
The Nature and Origin of Socioemotional Deficits in Schizophrenia	159	(20)
Elaine Walker
Karen M. Hochman
Neuroimaging Studies of Nonpsychotic First-Degree Relatives of People With Schizophrenia: Toward a Neurobiology of Vulnerability to Schizophrenia	179	(32)
Larry J. Seidman
Heidi E. Wencel
Colm McDonald
Robin M. Murray
Ming T. Tsuang
Neurophysiological Endophenotypes in Early Detection of Schizophrenia	211	(14)
Marina Myles-Worsley
Is the Development of Schizophrenia Predictable?	225	(30)
Paola Dazzan
Eugenia Kravariti
Paul Fearon
Robin M. Murray
Part III. Early Intervention and Prevention of Schizophrenia
Prevention of Schizophrenia and Psychotic Behavior: Definitions and Methodological Issues	255	(30)
C. Hendricks Brown
Stephen V. Faraone
The Treatment of Schizotaxia	285	(18)
Ming T. Tsuang
Sarah I. Tarbox
Levi Taylor
William S. Stone
Treatment of the Schizophrenia Prodrome	303	(22)
Barbara Cornblatt
Todd Lencz
Christopher Smith
Andrea Auther
The Role of Genetic Counseling	325	(14)
Debby W. Tsuang
Stephen V. Faraone
Ming T. Tsuang
Part IV. Challenges for the Near Future
The Biology of Schizotaxia	339	(16)
William S. Stone
Stephen J. Glatt
Stephen V. Faraone
Molecular Medicine and the Prospects for Prevention and Early Intervention in Schizophrenia	355	(12)
William T. Carpenter, Jr.
James I. Koenig
Index	367