The Early Course of Schizophrenia

by Sharma, Tonmoy; Harvey, Phil

• ISBN13: 9780198568957
• ISBN10: 0198568959
• Format: Paperback
• Copyright: 2006-04-20
• Publisher: Oxford University Press

Summary

New developments in the basic and clinical neurosciences have lead to important advances in our understanding of the events that occur between conception and birth that can influence schizophrenia. At the other end of the life span, some of the most exciting developments in years have recently been coming out of comprehensive studies of post-mortem studies of patients with schizophrenia. In the clinical domain, studies of first episode patients with schizophrenia are proliferating, at the same time as many research groups are performing comprehensive studies of patients with schizophrenia who are in the eighth decade of life or even older. Thus, many of the exciting new developments in research on schizophrenia are at the ends of the life span, suggesting that a wide-ranging treatment of schizophrenia in this framework will be very well accepted.

Table of Contents

Schizophrenia in the premorbid period
Prenatal events that influence schizophrenia	p. 3
Interactions of genetic predisposition and intrauterine events in the etiology of schizophrenia	p. 19
Cognitive functioning before or at the onset of the first episode	p. 41
Schizophrenia at the time of the first episode
Early onset schizophrenia: cognitive and clinical characteristics	p. 59
Brain imaging studies in childhood-onset schizophrenia	p. 71
Neurocognitive deficits and first-episode schizophrenia: characterization and course	p. 87
Structural and functional brain abnormalities in first-episode schizophrenia	p. 111
Diagnostic variability in the early course of schizophrenia	p. 131
Sex differences in schizophrenia: the case for developmental origins and etiological implications	p. 147
Late-onset schizophrenia: characteristics of patients at the first episode	p. 175
Treatment of early schizophrenia
Prodromal period: pharmacological and behavioural interventions	p. 189
Treatment of schizophrenia at the first episode	p. 211
Treatment of late-onset schizophrenia	p. 225
Treatment of cognitive deficits in first episode psychosis	p. 237
Index	p. 255
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