Introduction | p. 1 |
Reasons for Writing This Book | p. 1 |
Audiences for the Book | p. 5 |
Organization of the Book | p. 6 |
Economics | p. 9 |
A Broad View of Economics | p. 9 |
The Building Blocks of Economics | p. 11 |
The Concept of Scarcity | p. 11 |
The Concept of Opportunity Cost | p. 13 |
The Concept of Efficiency | p. 17 |
The Concept of Competitive Markets | p. 18 |
The Concept of Market Failure | p. 22 |
The Concept of Economic Appraisal | p. 24 |
Conclusions | p. 25 |
Health Economics | p. 27 |
Origins and Content of Health Economics | p. 27 |
The Parts of Health Economics Most Useful for Infection-Control | p. 30 |
Competing Approaches to Economic Appraisal | p. 32 |
Welfarism | p. 33 |
Extra-Welfarism | p. 35 |
Advantages and Disadvantages of Each Type of Economic Appraisal | p. 36 |
Conclusions | p. 37 |
Economic Appraisal: A General Framework | p. 39 |
What an Economic Appraisal Looks Like | p. 39 |
Incremental Analysis | p. 43 |
Ceiling Rations and Choosing Healthcare Programs | p. 46 |
Conclusions | p. 48 |
Economic Appraisal: The Nuts and Bolts | p. 49 |
Using a Clinical Trial vs. a Modeling Study | p. 49 |
Economic Appraisal Alongside Clinical Trials | p. 49 |
Economic Appraisal by Modeling Study | p. 50 |
Building a Model | p. 52 |
Objective 1: Define the Structure of the Model | p. 53 |
Objective 2: Find the Evidence Required to Make the Decision | p. 54 |
Objective 3: Evaluate the Model that has been Designed | p. 56 |
Objective 4: Account for Heterogeneity and Uncertainty | p. 59 |
Objective 5: Value Future Research | p. 63 |
Important Features of an Economic Appraisal | p. 63 |
Conclusions | p. 65 |
Changes Arising from the Adoption of Infection Control Programs | p. 67 |
Overview of the Major Changes | p. 67 |
Changes to the Number of Infections | p. 70 |
Epidemiological Studies | p. 70 |
Synthesizing Existing Evidence | p. 71 |
Conclusions | p. 75 |
Measuring the Cost of Healthcare Acquired Infections | p. 77 |
Why Data on the Cost of Hai are Useful | p. 77 |
Defining and Measuring Costs of HAI | p. 78 |
The Cost Accountant's Method | p. 78 |
The Economist's Method | p. 83 |
Differences Between the Cost Accounting and Economics Methods | p. 87 |
Estimating the Increase in Length of Stay due to HAI | p. 88 |
Design Approaches | p. 90 |
Statistical Approaches | p. 92 |
Conclusions | p. 96 |
Measuring the Cost of Implementing Infection Control Programs | p. 97 |
Estimating the Costs of Infection Control Programs | p. 97 |
Two Case Studies for Estimating the Cost of Infection Control | p. 98 |
A Case Study of the Costs of Adopting Antimicrobial Catheters | p. 98 |
A Case Study of the Costs of a Staff Education Program | p. 100 |
Analyzing Costs, Inputs, and Outputs | p. 101 |
Incremental Costs | p. 103 |
Average Costs | p. 105 |
Cost Data and Decision Making | p. 105 |
Capital Costs | p. 106 |
Conclusions | p. 107 |
Preventing HAI and the Health Benefits that Result | p. 109 |
Health Benefits | p. 109 |
What QALYs are and How they are Estimated | p. 109 |
Information Required to Estimate QALYs | p. 116 |
The Risk of Death due to Infection | p. 116 |
The Nature of the Health States and the Methods for Finding Utility Scores that Describe Them | p. 117 |
Conclusions | p. 122 |
Dissecting a Published Economic Appraisal | p. 123 |
Economic Evaluation in the Infection Control Literature | p. 123 |
Case Study of a Decision to Adopt Antimicrobial Central Venous Catheters | p. 124 |
Structuring the Evaluation | p. 124 |
Evidence Required for the Evaluation | p. 128 |
Epidemiological Parameters | p. 129 |
Effectiveness of Antimicrobial CVCs | p. 129 |
Costs | p. 130 |
Health Outcomes | p. 132 |
Evaluating the Decision | p. 132 |
Handling Uncertainty in the Decision | p. 133 |
Parameter Uncertainty | p. 134 |
Data Quality | p. 135 |
Generalizability | p. 136 |
Interpreting the Results for Decision Making | p. 136 |
Conclusions | p. 137 |
Economic Facts and the Infection Control Environment | p. 139 |
The Changing Infection Control Environment | p. 139 |
The Economic Facts | p. 141 |
Diminishing Returns | p. 141 |
Cost Structures | p. 144 |
Lack of Good Information | p. 147 |
Incentives for Bad Behavior | p. 148 |
Good Decision Making for Infection Control | p. 149 |
Conclusions | p. 152 |
Appendix | p. 153 |
References | p. 155 |
Index | p. 161 |
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