Electrokinetic Phenomena: Principles and Applications in Analytical Chemistry and Microchip Technology

by Rathore; Anurag S.

• ISBN13: 9780824743062
• ISBN10: 0824743067
• Edition: 1st
• Format: Hardcover
• Copyright: 2003-09-16
• Publisher: CRC Press

Summary

Electrokinetic Phenomena emphasizes the impact of methods such as capillary zone electrophoresis, capillary electrochromatography, and capillary gel electrophoresis on the analysis of biomolecules. This reference reveals the electrokinetic phenomena that underlie high-performance electro-based analytical tools and vividly depicts how electrodriven analytical tools revolutionize and expedite chemical, pharmaceutical, and biotechnological analysis. An authoritative overview, the book provides effective pathways for large-scale biomedical applications and describes how microfabricated and automated devices enhance and accelerate the analysis of biologically important molecules.

Table of Contents

Foreword
Barry L. Karger	iii
Preface	vii
Contributors	xiii
1. Migration of Sample Components in Capillary Analytical Techniques: Chromatography, Electrophoresis, and Electrochromatography	1	(14)
Anurag S. Rathore
2. Methods Development for Capillary Electrophoresis with Emphasis on Small Molecules	15	(28)
Robert Weinberger
3. Capillary Isoelectric Focusing	43	(26)
Ferenc Kilár
4. Capillary Gel Electrophoresis and Related Microseparation Techniques	69	(40)
András Guttman
5. Affinity Capillary Electrophoresis	109	(32)
Vadim M. Okun and Ernst Kenndler
6. Electroosmotic Mobility and Conductivity in Microchannels	141	(26)
Emily Wen, Anurag S. Rathore, and Csaba Horváth
7. Factors Influencing Performance in Capillary Electrochromatography on Silica Columns	167	(22)
Keith D. Bartle and Peter Myers
8. Effects of Pore Flow on Separation Efficiency in Capillary Electrochromatography with Porous Particles	189	(22)
Remco Stol and Wim Th. Kok
9. Ultrashort-Column Capillary Electrochromatography	211	(12)
Takao Tsuda
10. Microstructure and In-Silico Developments for High-Sensitivity Proteomics Research	223	(30)
Thomas Laurell, Johan Nilsson, and György Marko-Varga
11. Micro Chemical Processing on Microchips	253	(24)
Yoshikuni Kikutani and Takehiko Kitamori
12. Micropreparative Applications and On-Line Sample Treatment	277	(34)
Julia Khandurina
13. NMR Detection in Capillary Electrophoresis and Capillary Electrochromatography	311	(34)
Dimuthu A. Jayawickrama, Andrew M. Wolters, and Jonathan V. Sweedler
14. Applications of Capillary Electrochromatography	345	(82)
V.T. Remcho, Stacey L. Clark, Angela Doneau, and Gabriela S. Chirica
15. Clinical Applications of Microfluidic Devices	427	(44)
Joan M. Bienvenue, James Karlinsey, James P. Landers, and Jerome P. Ferrance
Index	471