Ending Aging The Rejuvenation Breakthroughs That Could Reverse Human Aging in Our Lifetime

by de Grey, Aubrey; Rae, Michael

• ISBN13: 9780312367077
• ISBN10: 0312367074
• Edition: 1st
• Format: Paperback
• Copyright: 2008-10-14
• Publisher: St. Martin's Griffin

Summary

With a New Afterword Must We Age? Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely'”technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future'”is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that -damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

Author Biography

Aubrey de Grey, Ph.D., is chairman and chief science officer of the Methuselah Foundation, and editor-in-chief of Rejuvenation Research, the only peer-reviewed academic journal focusing on intervention in aging. He has formulated a wide-ranging plan for the comprehensive and eventually indefinite postponement of age-related physical and mental decline, named SENS (Strategies for Engineered Negligible Senescence). He is the organizer of an ongoing series of conferences and workshops that focus on the key biomedical research relevant to SENS, and he also oversees the Methuselah Foundation’s growing sponsorship of SENS research worldwide.

Michael Rae is Dr. de Grey’s research assistant. He is a longtime member and onetime board member of the Calorie Restriction Society, a main contributor to the society’s “How-to Guide,” and a core scientific investigator with the society’s Cohort Study, which seeks to document the feasibility of calorie restriction in humans and the potential human translatability of the anti-aging effects observed in laboratory organisms.

Table of Contents

Preface	p. xi
	p. 1
The Eureka Moment	p. 3
Wake Up-Aging Kills!	p. 7
Demystifying Aging	p. 16
Engineering Rejuvenation	p. 32
	p. 47
Meltdown of the Cellular Power Plants	p. 49
Getting Off the Grid	p. 77
Upgrading the Biological Incinerators	p. 101
Cutting Free of the Cellular Spider Webs	p. 134
Breaking the Shackles of AGE	p. 164
Putting the Zombies to Rest	p. 200
New Cells for Old	p. 238
Nuclear Mutations and the Total Defeat of Cancer	p. 274
	p. 309
Getting from Here to There: The War on Aging	p. 311
Bootstrapping Our Way to an Ageless Future	p. 325
War Bonds for the Campaign Against Aging	p. 335
Afterword	p. 340
Notes	p. 379
Glossary	p. 405
Index	p. 421
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