Endocytosis

by Dautry-varsat, A. (CON); Gruenberg, J. (CON); Mata, L. (CON); Marsh, M. (CON); Ryter, A. (CON)

• ISBN13: 9783642842979
• ISBN10: 3642842976
• Format: Paperback
• Copyright: 2012-02-02
• Publisher: Springer Verlag

Summary

This book provides an updated and comprehensive view ofbasic and applied aspects of endocytosis.The first section covers new developments obtained bymolecular tracking of defined probes in microcinematographyand high-resolution electronmicroscopy, new procedures incell fractionation, cell-free assays and genetic engineeringof receptors transfected into eucaryotic cells. It alsodescribes endocytosis in non-mammalian cells.The second section explores several applications to theunderstanding of health and disease, especially in theimmune response and the relations between cells andintracellular pathogens, including in immunodeficientpatients. It also discusses toxins and explorestheirpotential for immunotoxins, as well as the development ofbetter designed drugs.