Epidemiologic Methods for the Study of Infectious Diseases

by Thomas, James C.; Weber, David J.

• ISBN13: 9780195121124
• ISBN10: 0195121120
• Edition: 1st
• Format: Hardcover
• Copyright: 2001-03-22
• Publisher: Oxford University Press

Summary

This is the first comprehensive text on the methodological issues in epidemiologic research on infectious diseases. It will be an invaluable resource both to students of epidemiology and to established researchers. The authors address such questions as: What needs to be considered whenenrolling participants in a study of sexually transmitted diseases? What are common sources of measurement error in population-based studies of respiratory infections? What are some sources of existing data for epidemiologic studies of infectious diseases? Answers to these and many other relatedquestions can be found in this well-organized, comprehensive and authoritative volume - the first to thoroughly address the methodologic issues in conducting epidimiologic research on infectious diseases. The book will be an ideal complement to texts on general epidemiology and infectious disease.An introductory section will make it accessible to a wide variety of disciplines by providing an overview of topics that are foundational to understanding infectious disease epidemiology, such as the immunology of infections, the biology of infectious diseases, and concepts of causation,transmission, and dynamics. The rest of the book is structured around sections on data sources and measurement; methods by transmission type; outbreak investigation and evaluation research; and special topics such as HIV/AIDS research, infections in the elderly, and research collaborations indeveloping countries.

Table of Contents

Part I Foundations
Biological Basis of Infectious Disease Epidemiology	3	(25)
David J. Weber
William A. Rutala
Immune Response and Methods for Detection of Infectious Diseases	28	(15)
Amy L. Peace-Brewer
Kimberly L. Kane
James D. Folds
Theories of Causation	43	(13)
Dana Loomis
Steve Wing
Concepts of Transmission and Dynamics	56	(30)
M. Elizabeth Halloran
Overview of Study Design	86	(33)
M. Elizabeth Halloran
Part II Data Sources and Measurement
Sources of Data	119	(19)
D. Peter Drotman
Marc A. Strassburg
Disease Surveillance	138	(25)
Terence L. Chorba
Microbial Molecular Techniques	163	(29)
Loreen A. Herwaldt
Michael A. Pfaller
Stefan Weber
Evaluation of Diagnostic Tests	192	(21)
Robert H. Fletcher
Scott B. Halstead
Part III Methods by Transmission Type
Respiratory Transmission	213	(15)
Jack M. Gwaltney, Jr.
J. Owen Hendley
Fecal-Oral Transmission	228	(21)
Karin E. Byers
Richard L. Guerrant
Barry M. Farr
Vector-Borne Transmission	249	(18)
Frank J. Sorvillo
Amy C. Morrison
O. G. W. Berlin
Sexual Transmission	267	(24)
James C. Thomas
Sara Stratton
Part IV Outbreak Investigation and Evaluation Research
Investigation of Outbreaks	291	(20)
David J. Weber
L. Bernardo Menajovsky
Richard Wenzel
Clinical Trials	311	(17)
Harry A. Guess
Gary B. Calandra
Community Intervention Studies	328	(16)
James C. Thomas
Evaluation of Immunization Programs	344	(31)
Robert T. Chen
Walter A. Orenstein
Part V Research in Special Populations or Settings
Research in Out-of-Home Child Care	375	(19)
Ralph L. Cordell
Larry K. Pickering
M. Louise Lawson
Infections Among the Elderly	394	(10)
Laura C. Hanson
HIV/AIDS Research	404	(27)
Sten H. Vermund
Howard Wiener
M. Louise Lawson
Madhav P. Bhatta
Research Collaborations in Developing Countries	431	(18)
Maria J. Wawer
Glossary	449	(6)
Acknowledgments and Credits	455	(2)
Index	457