Epidemiology of the Rheumatic Diseases

by Silman, Alan J.; Hochberg, Marc C.

• ISBN13: 9780192631497
• ISBN10: 0192631497
• Edition: 2nd
• Format: Hardcover
• Copyright: 2002-02-01
• Publisher: Oxford University Press

Summary

Epidemiology of Rheumatic Diseases 2e summarizes all the available data on the occurrence and risk factors for the major epidemiological, musculoskeletal, connective tissue and bone disorders. The aim is to provide a comprehensive overview of published data world-wide and include suchaspects as temporal and geographical trends in disease, contribution of genetic, constitutional and environmental factors to disease occurrence as well as the influence of traditional epidemiological risk factors such as age and gender. The available data is critically appraised to provide thereader with some information as to the relative robustness of the published material. Since the first edition was published in 1993 there have been major advances in all the subject areas covered in the book. As a consequence much of the original material is now out of date and the book has beenextensively re-written. Additional chapters have been added on systemic vasculitis and Paget's disease and much more attention has been given to neck and upper limb pain disorders as well as chronic widespread pain and fibromyalgia. In addition a new chapter has been provided reviewing populationstudies as a whole of musculoskeletal morbidity. The authors have also taken the opportunity to completely rewrite the section on genetics taking advantage of the tremendous advances in this area.

Table of Contents

Foreword	viii
Acknowledgements	ix
Introduction	1	(4)
Scope of epidemiology
Problems in undertaking rheumatic disease epidemiology
Scope of this volume
Population studies of musculoskeletal morbidity	5	(26)
Introduction
Population-based studies---methodological issues
Sources of data
Population studies of general musculoskeletal morbidity
Population studies of locomotor disability
Risk factors
Summary
PART I: Inflammatory joint disease
Rheumatoid arthritis	31	(41)
Criteria for diagnosis
Occurrence
Time trends
Genetic factors
Influence of pregnancy and sex hormones
Environmental factors
Juvenile idiopathic arthritis	72	(13)
Introduction
Classification
Incidence
Prevalence
Genetics
Non-genetic factors
Psoriatic arthropathy	85	(15)
Introduction
Occurence
Race and geography
Genetics
Environmental factors
Ankylosing spondylitis and spondyloarthropathics	100	(12)
Introduction
Classification criteria
Occurrence
Genetic factors
Non-genetic host factors
Environmental factors
Reactive arthritis and Reiter's syndrome	112	(11)
Classification criteria
Population occurrence
Risk factors: infection
Genetic factors
PART II: Connective tissue diseases
Systemic lupus erythematosus	123	(18)
Classification criteria
Occurrence
Genetic factors
Non-genetic host factors
Environmental factors
Scleroderma	141	(22)
Disease definition and criteria
Occurrence
Non-genetic host factors
Genetics
Environmental factors
Polymyositis/dermatomyositis	163	(11)
Classification criteria
Descriptive epidemiology
Genetics
Non-genetic host factors
Environmental factors
Systemic vasculitis	174	(14)
Introduction
Classification and criteria
Large vessel disease: Takayasu's arteritis
Medium and small vessel disease: PAN and MPA
Small vessel disease: WG
Small vessel disease: Churg-Strauss syndrome
Polymyalgia rheumatica and giant cell arteritis	188	(17)
Disease definition and criteria
Occurrence
Non-genetic host factors
Genetics
Environmental factors
PART III: Degenerative and metabolic bone and joint diseases
Osteoarthritis	205	(25)
Classification
Morbidity
Mortality
Risk factors
Genetic factors
Non-genetic host factors
Environmental factors
Prognosis
Gout	230	(17)
Classification criteria
Occurrence
Risk factors
Prognosis
Calcium pyrophosphate dihydrate (CPPD) deposition disease	247	(12)
Prognosis
Occurrence
Genetics
Non-genetic host factors
Osteoporosis	259	(34)
Introduction
Occurrence: health burden
Occurrence: epidemiology of fractures
Determinants of fracture risk
Bone mineral density and fracture
Falls and fracture
Risk factors for osteoporosis
Conclusion
Paget's disease	293	(16)
Introduction
Diagnostic criteria
Occurrence
Genetic factors
Environmental factors
PART IV: Regional and widespread pain disorders
Back pain	309	(30)
Introduction
Assessing back pain in populations
Classification of back pain (sufferers)
Grading and staging of back pain in surveys
Occurrence prevalence
Risk factors
Upper limb disorders	339	(28)
Classification criteria of upper limb disorders
Shoulder and neck pain
Forearm pain
Hand and wrist syndromes
Other upper limb conditions
Chronic widespread pain and fibromyalgia	367	(12)
Definition and classification
Prevalence of chronic widespread pain and fibromyalgia
Risk factors for chronic widespread pain and fibromyalgia
Index	379