did-you-know? rent-now

Amazon no longer offers textbook rentals. We do!

did-you-know? rent-now

Amazon no longer offers textbook rentals. We do!

We're the #1 textbook rental company. Let us show you why.

9783764386948

Erythropoietins, Erythropoietic Factors, and Erythropoiesis

by ; ;
  • ISBN13:

    9783764386948

  • ISBN10:

    3764386940

  • Edition: 2nd
  • Format: Hardcover
  • Copyright: 2009-06-15
  • Publisher: Birkhauser

Note: Supplemental materials are not guaranteed with Rental or Used book purchases.

Purchase Benefits

  • Free Shipping Icon Free Shipping On Orders Over $35!
    Your order must be $35 or more to qualify for free economy shipping. Bulk sales, PO's, Marketplace items, eBooks and apparel do not qualify for this offer.
  • eCampus.com Logo Get Rewarded for Ordering Your Textbooks! Enroll Now
  • Write a Review Icon Write a Review
List Price: $279.99 Save up to $84.00
  • Rent Book $195.99
    Add to Cart Free Shipping Icon Free Shipping

    TERM
    PRICE
    DUE
    SPECIAL ORDER: 1-2 WEEKS
    *This item is part of an exclusive publisher rental program and requires an additional convenience fee. This fee will be reflected in the shopping cart.

Supplemental Materials

What is included with this book?

Summary

This second edition is a one-source guide to current information about red blood cell physiology and the action of native and recombinant human erythropoietic factors. Topics in the fields of erythropoiesis, recombinant protein discovery and production, and treatment of patients with anemia due to renal failure, cancer, or chronic diseases are covered. The newest theories in erythropoiesis (receptors, signaling), manufacturing, new formulations, and clinical research are discussed.This book is of interest to researchers and clinical investigators in academia and biotechnology and pharmaceutical companies, to clinical research associates, clinical monitors, and physician investigators.

Table of Contents

List of contributorsp. VII
Preface to the first editionp. IX
Preface to the second editionp. XIII
Abbreviationsp. XV
Background
Erythropoiesis: an overviewp. 3
Regulation of endogenous erythropoietin productionp. 19
Biology of erythropoietinp. 41
Erythropoiesis - genetic abnormalitiesp. 61
Erythropoiesis-stimulating agents
Studies of erythropoiesis and the discovery and cloning of recombinant human erythropoietinp. 77
Commercial production of recombinant erythropoietinsp. 87
Biosimilar epoetinsp. 105
New molecules and formulationsp. 115
Erythropoietin receptor
Structural basis for the signal transduction of erythropoietinp. 143
Intracellular signaling by the erythropoietin receptorp. 155
Mechanism of erythropoietin receptor activationp. 175
Clinical utility
Pharmacokinetics of erythropoiesis-stimulating agentsp. 199
Use of erythropoietic stimulating agents in the setting of renal diseasep. 225
Abuse of recombinant erythropoietins and blood products by athletesp. 249
Role and regulation of iron metabolism in erythropoiesis and diseasep. 279
Nonhematopoietic effects of erythropoiesis-stimulating agentsp. 299
Indexp. 319
Table of Contents provided by Ingram. All Rights Reserved.

Supplemental Materials

What is included with this book?

The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.

The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.

Rewards Program