Essential BAT Value Documentations : From the MAK-Collection for Occupational Health and Safety

by Editor: Hans Drexler (Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area, Erlangen, Germany); Editor: Helmut Greim (Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area, Fr

• ISBN13: 9783527314775
• ISBN10: 3527314776
• Format: Hardcover
• Copyright: 2006-05-01
• Publisher: Vch Verlagsgesellschaft Mbh
• More Book Details
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Summary

For more than 20 of the most important occupational toxicants, the documentations for the established BAT values (Biological Exposure Values) and EKA values (Exposure Equivalents for Carcinogenic Substances) are provided. These include an authoritative review of the available toxicological studies and data. For every substance, metabolism and pharmacokinetics, critical toxicity, exposure and effects, suitable indicators of internal exposure, the evaluation of the BAT value and the correct interpretation of data are described. Basic physico-chemical data are provided as well. The documentations are thus not only essential for the application of BAT and EKA values but provide a concise overview of biological monitoring for each substance. The documentations are authoritative, because they were compiled by the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area. The Commission is internationally acknowledged for its neutrality and is working strictly according to transparent, scientific criteria. BAT Values set the standards for legal regulations in many countries of the world, e. g. they are the basis for at least 30 % of the threshold limits valid in the European Union.

Author Biography

Hans Drexler is head of the working group "Setting of Threshold Limit Values in Biological Materials" of the Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area and Director of the Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine of the University of Erlangen-Nuremberg (Germany). He is board member of the International Society of Environmental Medicine (ISEM) and Editor-in-chief of the International Archives of Occupational and Environmental Health.

Helmut Greim is Head of the DFG-Senate Commission for the Investigation of Health Hazards of Chemical Compounds in the Work Area and also President of the Advisory Committee on Existing Chemicals of Environmental Relevance of the German Chemical Society. Both bodies are intimately involved in European regulatory procedures concerning hazardous chemicals.

Table of Contents

General Aspects
Concepts of Biological Limit Values -- The BAT Concept	3	(5)
The BLW Concept (Biologischer Leitwert)	8	(5)
The EKA Concept -- Exposure Equivalent for Carcinogenic Substances (Expositionsaquivalent fur krebserzeugende Arbeitsstoffe)	13	(2)
Comparison of the BAT and EKA Values with the American Biological Exposure Indices (BEIs)	15	(6)
Quality Control of Biological Monitoring in Occupational Medicine	21	(14)
Substances
Acetone	35	(14)
Alkali chromates (Cr(VI))	49	(18)
Aniline	67	(10)
Arsenic and inorganic arsenic compounds (with the exception of arsenic hydride and its salts)	77	(8)
Arsenic trioxide	85	(14)
Benzene	99	(16)
2-Butanone	115	(8)
2-Butoxyethanol	123	(14)
Cobalt	137	(12)
Cresols (all isomers)	149	(10)
Cyclohexane	159	(10)
4,4'-Diaminodiphenylmethane	169	(10)
Dimethyl sulfate	179	(8)
Ethylene oxide	187	(8)
Hydrogen fluoride and inorganic fluorine compounds (Fluorides)	195	(10)
Lead and its compounds (except lead arsenate, lead chromate and alkyllead compounds)	205	(40)
Lead and its compounds, Addendum (except lead arsenate, lead chromate and alkyllead compounds)	245	(8)
Lead and its compounds (except lead arsenate, lead chromate and alkyllead compounds)	253	(2)
Methanol	255	(16)
Nickel and sparingly soluble nickel compounds (Nickel as nickel metal, nickel sulphide, sulphidic ores, nickel oxide, nickel carbonate)	271	(12)
2-Propanol	283	(10)
Styrene	293	(16)
Addendum to Styrene	309	(6)
Tetrachloroethene	315	(14)
Tetrachloroethene, Addendum	329	(4)
Vinyl chloride	333	(8)
Xylenes	341	(14)
Index for Volumes 1--4	355