Essentials of General, Organic and Biochemistry

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  • Edition: 1st
  • Format: Hardcover
  • Copyright: 2009-09-15
  • Publisher: W. H. Freeman
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Teaching all of the necessary concepts within the constraints of a one-term chemistry course can be challenging. Authors Denise Guinn and Rebecca Brewer have drawn on their 14 years of experience with the one-term course to write a textbook that incorporates biochemistry and organic chemistry throughout each chapter, emphasizes cases related to allied health, and provides students with the practical quantitative skills they will need in their professional lives. Essentials of General, Organic, and Biochemistrycaptures student interest from day one, with a focus on attention-getting applications relevant to health care professionals and as much pertinent chemistry as is reasonably possible in a one term course. Students value their experience with chemistry, getting a true sense of just how relevant it is to their chosen profession.

Table of Contents

Chapter One: Measurement , Atoms, and the Periodic Table
What Happens When You Don’t Get Enough Iron?
1.1 Measurement and the Metric System
1.2 The Structure of the Atom
1.3 Elements
1.4 The Periodic Table of the Elements
Chemistry in Medicine: The Micronutrients
The Model Tool 1.1: The Building Block Elements
Extension Topic 1.1: Converting Between Units of Moles and Mass of an Element

Chapter Two: Ionic and Covalent Compounds
What is in Your Morning Coffee?
2.1 Ionic Compounds
2.2 Covalent Molecules
2.3 Writing Lewis Dot Structures
2.5 Molecular Mass, Formula Mass, and Molar Mass
Chemistry in Medicine: Blood Chemistry and the Diagnosis of Disease
The Model Tool 2.1: Covalent Bonds in Molecules
Extension Topic 2.1: Converting Between Moles and Mass

Chapter Three: Molecular Shape and Intermolecular Forces
Breast Cancer and the Shapes of Molecules
3.1 Three Dimensional Shapes of Molecules
3.2 Polar Covalent Bonds and Polar Molecules
3.3 Intermolecular Forces of Attraction
Chemistry in Medicine: The Estrogen Receptor and Hormone Therapy in the Treatment of Breast Cancer
The Model Tool 3.1: The Linear Geometry
The Model Tool 3.2: The Trigonal Planar Geometry
The Model Tool 3.3: The Tetrahedral Geometry
The Model Tool 3.4: The Trigonal Pyramidal Geometry
The Model Tool 3.5: The Bent Geometry
The Model Tool 3.6: Larger Molecule Shapes

Chapter Four: States of Matter
Diver Rescue: “The Bends”
4.1 States of Matter 
4.2 Energy
4.3 Changes of State
4.5 Gases
Chemistry in Medicine: Hyperbaric Oxygen Therapy

Chapter Five: Solutions, Col loids, and Membranes
Kidney Disease
5.1 Mixtures and Solutions
5.2 Concentration of Solutions
5.3 Colloids and Suspensions
5.4 Processes that Maintain Biochemical Balance in Your Body
Chemistry in Medicine: Kidney Dialysis
Extension Topic 5.1: Converting between Different Concentration Units

Chapter Six: Organic Chemist ry Part I : Hydrocarbons and Structure
The Effects of Anabolic Steroids on the Body
6.1 Hydrocarbons
6.2 Alkanes
6.3 Alkene
6.4 Alkynes
6.5 Aromatic Hydrocarbons
Chemistry in Medicine
The Model Tool 6.1: Alkane Conformations
The Model Tool 6.2: Structural Isomers
The Model Tool 6.3: Alkanes and Cycloalkanes
The Model Tool 6.4: Geometric Isomers
The Model Tool 6.5: Benzene and Substituted Benzenes
Extension Topic 6.1: More on Naming Branched Chain Hydrocarbons
Extension Topic 6.2: Naming Cycloalkenes

Chapter Seven: Organic Chemistry Part I I : Functional Groups and Stereochemistry
Pain and the Opioid Analgesics
7.1 Carbon-Heteroatoms Single Bond Functonal Groups
7.2 C=O Containing Functional Groups
7.3 P=O Containing Functional Groups
7.4 Stereochemistry
Chemistry in Medicine: Schizophrenia and Parkinson’s Disease: The Role of Dopamine
The Model Tool 7.1: Alcohols and Ethers
The Model Tool 7.2: Amines
The Model Tool 7.3: The Carbonyl Group
The Model Tool 7.4: Enantiomers
The Model Tool 7.5: The Fischer Projection
Extension Topic 7.1: Assigning the IUPAC Name for an Amine
Extension Topic 7.2: Assigning the IUPAC Name for an Ester

Chapter Eight : Chemical Reactions, Energy, and Kinetics
Energy, Nutrition, and World Hunger
8.1 The Chemical Equation
8.2 Energy and Chemical Reactions
8.3 Kinetics: Reaction Rates
Chemistry in Medicine: Critical Needs for Human Calorimetry in Medicine
Model Tool 8.1: Balancing a Chemical Equation
Extension Topic 8.1: Reaction Stoichiometry

Chapter Nine: Acid, Bases, pH, and Buffers
Is your Garage a Safe Place for Your Pet?
9.1 Acids and Bases: Structure and definition
9.2 pH
9.3 Equilibrium
9.4 Acids and Bases: Strengths and Properties
9.5 Buffers
Chemistry in Medicine: Why Some Drugs Cannot be Administered Orally: The Issue of pH
The Model Tool 9.1: Equilibrium of a Weak Base

Chapter Ten: Reactions of Organic Functional Groups in Biochemistry
How Does Your Body Handle Alcoholic Beverages?
10.1 Oxidation-Reduction Reactions
10.2 Hydration-Dehydration Reactions
10.3 Acyl Group Transfer Reactions
10.4 Phosphoryl Group Transfer Reactions
10.5 The Role of the Coenzymes NADH and FADH2 in Biochemical Reactions
10.6 Recognizing Reactions in the Citric Acid Cycle
Chemistry in Medicine: Vitamins and Health
Model Tool 10.1: Acyl Transfer Reactions

Chapter Eleven: Proteins: Structure and Function
One Wrong Amino Acid: Sickle Cell Anemia
11.1 Amino Acids
11.2 Peptides
11.3 Proteins
11.4 Functions of Proteins: Enzymes
11.5 Metabolism of Proteins
Chemistry in Medicine: ACE Inhibitors—A Treatment for Hypertension
The Model Tool 11.1: A dipeptide

Chapter Twelve: Carbohydrates: Structure and Function
Blood Sugar—What Happens When it Gets Too High or Too Low?
12.1 Carbohydrate Structure
12.2 Carbohydrates Catabolism
12.3 Oligosaccharides as Cell Markers
Chemistry in Medicine: The Role of Glycogen in Exercise and Metabolism
The Model Tool 12.1: Glucose
The Model Tool 12.2: Maltose

Chapter Thirteen: Lipids: Structure and Function
Good Fats…Bad Fats…Trans Fats…What Does it all Mean?
13.1 Triglycerides: Fat Storage Lipids
13.2 Fatty Acid Catabolism
13.3 Membrane Lipids
13.4 Eicosanoids
13.5 Cholesterol and Other Steroid Hormones
Chemistry in Medicine: Cholesterol and Cardiovascular Disease

Chapter Fourteen: Metabol ism and Bioenergetics
The Role of Physical Activity in Weight Loss
14.1 The Key Molecules of Metabolism
14.2 The Citric Acid Cycle
14.3 The Electron Transport Chain and Oxidative Phosphorylation
14.4 Free Energy and Entropy in Bioenergetics
Chemistry in Medicine: Phenylketonuria

Chapter Fifteen: DNA and RNA
Gene Mutations and Disease
15.1 Parts of a Nucleotide and Nucleic Acids
15.2 DNA
15.3 RNA and Protein Synthesis
Chemistry in Medicine: Viral Nucleic Acids: the Case of HIV/AIDS

Chapter Sixteen: Nuclear Chemistry and Medicine
Diagnosing and Treating Cancer: The Powerful Role of Nuclear Chemistry
16.1 Radioisotopes and Nuclear Reactions
16.2 Biological Effects of Nuclear Radiation
16.3 Diagnosis of Medical Conditions
Chemistry in Medicine: Treating Cancer using Radiation

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