..Dr Deborah Robertson is Senior Lecturer at University of Chester School of Nursing, and is the Deputy Programme Leader Non Medical Prescribing. Her primary focus is pharmacology education pre and post registration and post graduate. Current research activity includes evaluation of non medical prescribing practice, participation in a North West Numeracy Consortium with the Strategic Health Authority to address issues of drug calculation in nursing. .
Introduction | p. ix |
About the Authors | p. x |
Pharmacodynamics and pharmacokinetics | p. 1 |
Learning Objectives | p. 1 |
Introduction | p. 2 |
Absorption | p. 2 |
Distribution | p. 4 |
Biotransformation | p. 4 |
Excretion | p. 5 |
General and molecular aspects | p. 5 |
Drug action | p. 6 |
Agonistic and antagonistic drug action | p. 7 |
Basic Introduction to units and conversions | p. 8 |
Case Studies | p. 10 |
Key learning points | p. 11 |
Calculations | p. 12 |
Multiple choice questions | p. 13 |
Recommended further reading | p. 14 |
Adverse drug reactions and interactions | p. 15 |
Learning Objectives | p. 15 |
Introduction | p. 16 |
Main Mechanisms of drug interactions | p. 16 |
Adverse drug reactions | p. 17 |
Clinical significance of drug interactions to the patient | p. 18 |
Major groups of drugs involved in adverse drug reactions | p. 18 |
Steps in minimizing the effects of adverse drug interactions | p. 19 |
Age-related adverse drug reactions | p. 19 |
Case studies | p. 21 |
Key learning points | p. 21 |
Multiple choice questions | p. 22 |
Recommend further reading | p. 24 |
Local anaethetics and analgesics | p. 25 |
Learning objectives | p. 25 |
Introduction | p. 26 |
Local anaesthetics | p. 31 |
Non-steroidal anti-inflammatory drugs | p. 35 |
Opioid analgesics | p. 37 |
Opioid antagonists | p. 38 |
Case studies | p. 39 |
Key learning points | p. 40 |
Calculations | p. 41 |
Multiple choice questions | p. 42 |
Recommended further reading | p. 43 |
Antimicrobials | p. 45 |
Learning objectives | p. 46 |
Introduction | p. 46 |
Interferance with folate | p. 48 |
Beta-lactam antibiotics | p. 48 |
Interference with protein synthesis | p. 49 |
Inhibition of bacterial DNA | p. 51 |
Drugs used to treat tuberculosis | p. 52 |
Virai disease | p. 54 |
Human immunodeficiency virus (HIV) | p. 54 |
Other antiviral drugs | p. 56 |
Fungal infections | p. 58 |
Antifungal drugs | p. 59 |
Protozoa | p. 62 |
Case studies | p. 65 |
Key learning points | p. 65 |
Calculations | p. 68 |
Multiple choice questions | p. 69 |
Recommended further reading | p. 70 |
Anti-inflammatory drugs | p. 73 |
Learning objectives | p. 73 |
Introduction | p. 74 |
Non-steroidal anti-infalmmatory drugs | p. 76 |
Cyclo-oxgenase pathway 2 inhibitors | p. 77 |
Asprin | p. 77 |
Paracetamol | p. 78 |
Histamine | p. 78 |
Steroids | p. 79 |
Antirheumatoid drugs | p. 80 |
Case studies | p. 83 |
Key learning points | p. 83 |
Calculations | p. 85 |
Multiple choice questions | p. 86 |
Recommended further reading | p. 88 |
Anticoagulant therapy | p. 89 |
Learning objectives | p. 89 |
Introduction | p. 90 |
Blood clotting and the development of thrombosis | p. 91 |
Drugs that act on the clotting cascade | p. 91 |
Case study | p. 96 |
Key learning points | p. 96 |
Calculations | p. 97 |
Multiple choice questions | p. 98 |
Recommended further reading | p. 99 |
Drugs used in chronic conditions | p. 101 |
Learning objectives | p. 102 |
Introduction | p. 102 |
Asthma | p. 102 |
Drugs used in treating asthma | p. 103 |
Diabetes | p. 107 |
Medicine management of diabetes | p. 109 |
Hypertension | p. 114 |
Parkinson's disease | p. 118 |
Epilepsy | p. 120 |
Case studies | p. 124 |
Key learning points | p. 125 |
Calculations | p. 126 |
Multiple choice questions | p. 127 |
Recommended further reading | p. 129 |
Drugs used in mental health | p. 131 |
Learning objectives | p. 131 |
Introduction | p. 132 |
Anxiety | p. 132 |
Medicine and management of anxiety | p. 133 |
Depression | p. 135 |
Medicine management of depression | p. 137 |
Psychosis | p. 140 |
Case studies | p. 144 |
Key learning points | p. 144 |
Calculations | p. 146 |
Multiple choice questions | p. 147 |
Recommended further reading | p. 148 |
Patient concordance | p. 149 |
Learning objectives | p. 149 |
Introduction | p. 149 |
Adherence, compliance and concordance | p. 150 |
Factors influencing effective medicine use and concordance | p. 150 |
Patient empowerment in chronic disease management | p. 152 |
Case studies | p. 155 |
Key learning points | p. 155 |
Calculations | p. 156 |
Multiple choice questions | p. 157 |
Recommended further reading | p. 158 |
Legal and Professional issues | p. 159 |
Learning objectives | p. 159 |
Introduction | p. 159 |
The correct patient | p. 160 |
The correct medicine | p. 160 |
The correct dose | p. 160 |
The correct site and method of administration | p. 161 |
Covert administration of medicines | p. 162 |
Alteration of medicines | p. 162 |
Reporting of drug errors | p. 163 |
Controlled drugs | p. 163 |
Supply and administration of medicines | p. 164 |
Prescribing law and non-medical prescribing | p. 165 |
Case studies | p. 166 |
Key learning points | p. 167 |
Multiple choice questions | p. 169 |
Recommended further reading | p. 170 |
Conclusion | p. 171 |
Glossary | p. 173 |
Answers | p. 175 |
Index | p. 183 |
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