The Ethical Dimensions of the Biological and Health Sciences

by Edited by Ruth Ellen Bulger , Elizabeth Heitman , Stanley Joel Reiser

• ISBN13: 9780521008860
• ISBN10: 0521008867
• Edition: 2nd
• Format: Paperback
• Copyright: 2002-06-24
• Publisher: Cambridge University Press

Summary

This is the second edition of a highly successful and well-received textbook on the responsible conduct of biomedical and health science research. It is aimed at faculty and graduate students in health science and biomedical science programs. In addition, those on National Institute of Health research grants, administrators at universities, and academic health centers will find it a useful resource. The major changes include new chapters providing overviews of each topic, several new published articles added to the readings, revised case studies as well as further readings and web addresses.

Table of Contents

Preface	xi
Section I Introduction to the Study of Ethics in the Biological and Health Sciences
The Ethics Movement in the Biological and Health Sciences: A New Voyage of Discovery	3	(18)
Stanley Joel Reiser
Section II The Roots of Honor and Integrity in Science
The Roots of Honor and Integrity in Science: Historical Themes in the Practical Ethics of Research	21	(8)
Elizabeth Heitman
The Ethical Basis of Science	29	(13)
Bentley Glass
Self-Deception and Gullibility	42	(15)
William Broad
Nicholas Wade
Questions for Discussion	54	(1)
Recommended Supplemental Reading	54	(3)
Section III The Responsible Conduct of Research
The Responsible Conduct of Biological and Health Research	57	(7)
Ruth Ellen Bulger
The Pathogenesis of Fraud in Medical Science	64	(4)
Robert G. Petersdorf
Science, Statistics, and Deception	68	(3)
John C. Bailar III
Innovation and Integrity in Biomedical Research	71	(7)
Sheila Jasanoff
Preventing Scientific Misconduct	78	(11)
Douglas L. Weed
Questions for Discussion	86	(1)
Recommended Supplemental Reading	86	(3)
Section IV The Ethics of Authorship and Publication
Ethical Practices in the Publication of Research Results	89	(8)
Ruth Ellen Bulger
An Ethical Code for Scientists	97	(8)
Ward Pigman
Emmett B. Carmichael
Irresponsible Authorship and Wasteful Publication	105	(4)
Edward J. Huth
Reporting Provocative Results: Can We Publish ``Hot'' Papers without Getting Burned?	109	(4)
James L. Mills
ORI Provides Working Definition of Plagiarism	113	(4)
Questions for Discussion	113	(1)
Recommended Supplemental Reading	114	(3)
Section V Research with Human Beings
Research with Human Beings	117	(9)
Ruth Ellen Bulger
The Nuremberg Code	126	(2)
The Belmont Report: Ethical Principles and Guidelines for the Protection of Human Subjects of Research	128	(11)
False Hopes and Best Data: Consent to Research and the Therapeutic Misconception	139	(9)
Paul S. Appelbaum
Loren H. Roth
Charles W. Lidz
Paul Benson
William Winslade
Declaration of Helsinki: Ethical Principles for Medical Research Involving Human Subjects	148	(7)
Questions for Discussion	151	(1)
Recommended Supplemental Reading	151	(4)
Section VI Ethics in Epidemiologic Research
Ethical Issues in Epidemiologic Research	155	(9)
Elizabeth Heitman
Protection of Research Subjects: Do Special Rules Apply in Epidemiology?	164	(11)
A. M. Capron
Limitations in the Use of Race in the Study of Disease Causation	175	(8)
Richard S. Cooper
Vincent L. Freemnn
Questions for Discussion	180	(1)
Recommended Supplemental Reading	180	(3)
Section VII The Humane Care and Use of Animals in Research
The Humane Care and Use of Animals in Research	183	(9)
Elizabeth Heitman
Beastly Conduct: Ethical Issues in Animal Experimentation	192	(11)
Arthur L. Caplan
Recognition and Alleviation of Pain and Distress in Laboratory Animals	203	(4)
2000 Report of the AVMA Panel on Euthanasia	207	(14)
Questions for Discussion	216	(1)
Recommended Supplemental Reading	216	(5)
Section VIII Management of and Access to Scientific Data
Ethical Issues in Data Acquisition, Access, and Management	221	(8)
Ruth Ellen Bulger
Sharing Research Data	229	(2)
Duncan Neuhauser
Retention of and Access to Research Data	231	(5)
Henry M. Jackson
Guidelines on Research Data and Reports	236	(11)
Questions for Discussion	242	(1)
Recommended Supplemental Reading	243	(4)
Section IX The Work of the Academic Scientist
The Work of the Academic Scientist	247	(8)
Ruth Ellen Bulger
Enlarging the Perspective	255	(8)
Ernest L. Boyer
Obstacles to Collegiality in the Academic Health Center	263	(4)
Roger James Bulger
Ruth Ellen Bulger
Integrity in the Education of Researchers	267	(7)
Terry Ann Krulwich
Paul J. Friedman
Administrative Case Rounds: Institutional Policies and Leaders Cast in a Different Light	274	(7)
Stanley Joel Reiser
Questions for Discussion	277	(1)
Recommended Supplemental Reading	277	(4)
Section X The Scientist and Industry
The Scientist and Industry: Conflicts of Interest and Conflicts of Commitment	281	(9)
Ruth Ellen Bulger
Patenting Life: Summary, Policy Issues, and Options for Congressional Action	290	(8)
Looking a Gift Horse in the Mouth: Corporate Gifts Supporting Life Sciences Research	298	(15)
Eric G. Campbell
Karen Seashore Louis
David Blumenthal
Questions for Discussion	308	(1)
Recommended Supplemental Reading	308	(5)
Section XI The Scientist in Society
The Scientist in Society: Interactions, Expectations, and Obligations	313	(7)
Ruth Ellen Bulger
Summary Statement of the Asilomar Conference on Recombinant DNA Molecules	320	(7)
Paul Berg
David Baltimore
Sydney Brenner
Richard O. Roblin III
Maxine F. Singer
Scientific Basis for the Support of Biomedical Science	327	(14)
Julius H. Comroe, Jr.
Robert D. Dripps
Genetics and Human Malleability	341	(8)
W. French Anderson
Questions for Discussion	345	(1)
Recommended Supplemental Reading	346	(3)
Section XII Cases for Discussion
Using Cases in the Study of Ethics	349	(16)
Elizabeth Heitman
Index	365