Extrapolation Practice for Ecotoxicological Effect Characterization of Chemicals

by Solomon; Keith R.

• ISBN13: 9781420073904
• ISBN10: 1420073907
• eBook ISBN(s): 9781000687705
• Additional ISBN(s): 9781420073928
• Edition: 1st
• Format: Hardcover
• Copyright: 2008-05-23
• Publisher: CRC Press
• More Book Details

Summary

A wide-ranging compilation of techniques, this book describes various methods of extrapolation in the framework of ecological risk assessment as well as identifies the data needs and situations where these extrapolations can be most useful applied. It focuses on the extrapolation of chemical effects and also covers the extrapolation of exposures in the context of interactions between toxicants and the matrix. It contains a practical guide to the application of these extrapolation procedures that is designed to be useful to regulators and risk managers at several levels and in the education of students in these environmental disciplines.

Table of Contents

List of Illustrations	p. ix
List of Tables	p. xiii
About the Editors	p. xv
Contributors and Workshop Participants	p. xxi
Preface	p. xxiii
Extrapolation in the Context of Criteria Setting and Risk Assessment	p. 1
Matrix and Media Extrapolation	p. 33
(Q)SAR and Extrapolation	p. 75
Extrapolation of Effects Measures across Levels of Biological Organization in Ecological Risk Assessment	p. 105
Mixture Extrapolation Approaches	p. 135
Temporal Extrapolation in Ecological Effect Assessment of Chemicals	p. 187
Spatial Extrapolation in Ecological Effect Assessment of Chemicals	p. 223
Conclusions	p. 257
Glossary	p. 269
Guidance on the Application of Extrapolation Methods in Ecological Exposure and Effects Characterization of Chemicals	p. 281
References	p. 323
Index	p. 369
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