Familial Cancer and Prevention Molecular Epidemiology: A New Strategy Toward Cancer Control

by Utsunomiya, Joji; Mulvihill, John J.; Weber, Walter

• ISBN13: 9780471249375
• ISBN10: 0471249378
• Edition: 1st
• Format: Hardcover
• Copyright: 1999-04-27
• Publisher: Wiley-Liss

Summary

Up-to-date, authoritative, and comprehensive, Familial Cancer and Prevention is an important working resource for clinicians, cancer researchers, and epidemiologists.

Author Biography

Joji Utsunomiya and John J. Mulvihill are the authors of Familial Cancer and Prevention: Molecular Epidemiology: A New Strategy Toward Cancer Control, published by Wiley.

Table of Contents

Preface	xiii
Utsunomiya
Weber
Mulvihill
Contributors	xix
PART 1 OVERVIEWS	1	(18)
Introduction	3	(2)
Max M. Burger
The UICC Familial Cancer and Prevention Project	5	(2)
Walter Weber
Molecular Epidemiology of Human Cancer	7	(12)
S. Perwez Hussain
Curtis C. Harris
PART 2 GENERAL STRATEGIES AND EXPERIENCE	19	(2)
PART 2A LOGISTICS	21	(60)
From Nurse to Nodal Points: The Rationale of a Questionnaire and Database to Collect, Validate, and Exchange Information on Familial Cancer	23	(4)
Davide Brunetti
Walter Weber
Collecting Information About Familial Cancer	27	(8)
Walter Weber
Peter Mussio
Hans Stoll
Object-Oriented Computer Software Linking a Pedigree Drawing Application and an Advanced Relational Database: The ``Progeny'' System	35	(8)
Jose A. Bufill
David S. Deram
Michael Brammer
Research and Clinical Care Networks in Neurofibromatosis	43	(4)
Bruce R. Korf
Identification of Genetic Predispositions to Cancer: A Swiss Experience	47	(4)
Pierre O. Chappuis
Anne Murphy
Murielle Saugy
Phillippe Maillet
Pierre Hutter
Andre-Pascal Sappino
The Oxford Cancer Genetic Clinic: Experience of the First Seven Years	51	(8)
George R. Fraser
Family History-Based Screening for Colorectal Cancer	59	(6)
D. James B. St. John
Cancer Genetic Clinics: Characteristics of 552 Consultees Attending a Center in the South East of France	65	(6)
Francois Eisinger
Claire Julian-Reynier
Francoise Chabal
Yvette Aurran
Hagay Sobol
Presymptomatic Testing: Efficacy of a Clinical Risk Assessment Program	71	(6)
Brian A. Clark
Graham Casey
Linda Webster
Hereditary Tumor Registry in Korea	77	(4)
Jae-Gahb Park
PART 2B COUNSELING ISSUES	81	(68)
Ethical Issues in Precancer Screening: The Parallel With Huntington Disease	83	(6)
Donna L. Dickenson
Cancer-Predisposition Genetic Testing: Clinical and Prevention Implications	89	(10)
Gloria M. Petersen
Genetic Counseling of Cancer Patients and Their Relatives: Issues and Practices	99	(6)
Hansjakob Muller
A Nursing Perspective of Counseling Families in a Cancer Genetics Clinic	105	(6)
Audrey Ardern-Jones
The Nurse's Role in Decision Making in Familial Cancer	111	(6)
Hans Stoll
Familial Cancer: New and Evolving Challenges for Oncology Nurses and Their Patients	117	(4)
Mary C. Fraser
Counseling Issues: The Role of the Genetic Counselor	121	(10)
Elizabeth Gettig
Genetic Counseling and Its Ethical Issues in Japan	131	(6)
Koji Ohkura
Bioethical Concerns With Rights of Patients Receiving Genetic Tests	137	(6)
Kazumasa Hoshino
Use of Genetic Information by Private Insurers	143	(6)
Robert J. Pokorski
PART 3 SPECIFIC FAMILIAL CANCERS	149	(2)
PART 3A COLORECTAL CANCER	151	(2)
PART 3A.1 Familial Adenomatous Polyposis	153	(44)
Surgical Management of Familial Adenomatous Polyposis	153	(10)
J. Utsunomiya
N. Gondo
Extracolonic Symptoms of Familial Adenomatous Polyposis and Their Association With a Slow Acetylation Phenotype	163	(8)
Rodney J. Scott
Walter Taeschner
Urs A. Meyer
Hansjakob Muller
Desmoid Disease in Familial Adenomatous Polyposis	171	(6)
Karen P. Nugent
Chemoprevention of Colorectal Adenomas in Familial Adenomatous Polyposis With Low-Dose Suldinac: Clinical Outcome, Influence on Oncogenes, and Growth Factors: Interim Results of a Five-Year Study Course	177	(14)
Guenther Winde
Kurt W. Schmid
Oliver Muller
Helmut Bartsch
Hans Osswald
Interventional Trial for Cancer Prevention for Familial Adenomatous Polyposis	191	(6)
Hideki Ishikawa
Ikuko Akedo
Kazushige Iseki
Takaichiro Suzuki
Toru Otani
PART 3A.2 Hereditary Nonpolyposis Colorectal Cancer (HNPCC)	197	(76)
HNPCC: Genetics, Counseling, Natural History, Surveillance, and Management	197	(10)
Henry T. Lynch
Kevin Lin
Thomas Smyrk
Patrice Watson
Alan Thorson
Maniamparampil Shashidharan
Barbara Franklin
Beth Karr
Jane F. Lynch
Susan Tinley
Stephen Lanspa
Stephen J. Lemon
Trudy Shaw
Miguel A. Rodriguez-Bigas
Colorectal Cancer Prognosis in Hereditary Nonpolyposis Colorectal Cancer	207	(4)
Patrice Watson
Kevin Lin
Miguel A. Rodriguez-Bigas
Henry T. Lynch
Defining the Clinical Phenotype of Hereditary Nonpolyposis Colorectal Cancer	211	(4)
Nicholas E. Beck
Ian P.M. Tomlinson
Walter F. Bodmer
Evolution of Neoplasia in Hereditary Nonpolyposis Colorectal Cancer	215	(6)
Jeremy R. Jass
Controversial Issues in Hereditary Nonpolyposis Colorectal Cancer	221	(6)
Shozo Baba
Joshi Nakamura
Kokichi Sugano
Masayuki Yasutomi
Yusuke Nakamura
Benign Extracolonic Manifestations Associated With Hereditary Nonpolyposis Colorectal Cancer	227	(6)
G. Moslein
D. Schaid
R. Dozois
H.-D. Roher
S. McDonnell
S. Thibodeau
Prevention of Hereditary Nonpolypotic Colorectal Cancer: Molecular Testing of Known Family Members and Molecular Screening in Sporadic Colorectal Cancer Patients	233	(4)
Albert de la Chappelle
Molecular Biology of Hereditary Nonpolyposis Colorectal Cancer	237	(8)
Yasuhito Yuasa
Yoshimitsu Akiyama
An Automated Genetic Assay for Hereditary Nonpolyposis Colorectal Cancer	245	(6)
Robert B. Chadwick
Paula Kristo
Antonio Percesepe
Jianguo Chen
Jason Stein
Mel Kronick
Complex Genetic Predisposition to Cancer in an Extended HNPCC Kindred with an Ancestral hMLH1 Mutation	251	(8)
Pierre Hutter
Pierre O. Chappuis
Alexia Couturier
Veronique Antonioli
Jean-Marie Buerstedde
Surveillance and Management of Hereditary Nonpolyposis Colorectal Cancer	259	(8)
H.F.A. Vasen
G. Griffioen
J. Wijnen
H. Boonstra
R. Fodde
P. Meera Khan
Genetic Diagnosis and Management of Suspected Hereditary Nonpolyposis Colorectal Cancer	267	(6)
Jae-Gahb Park
Ying Yuan
Hye-Jung Han
PART 3A.3 Prevention	273	(70)
Prophylatic Colectomy in Hereditary Nonpolyposis Colorectal Cancer	273	(6)
Miguel A. Rodriguez-Bigas
Concerted Action Polyp Prevention: A Trial of Aspirin and/or Resistant Starch in People at Risk of Hereditary Colon Cancer	279	(6)
J. Burn
P.D. Chapman
D.T. Bishop
J. Mathers
Dietary Prevention of Colorectal Cancer	285	(6)
Finlay Macrae
Calcium in Cancer Prevention	291	(4)
Martin Lipkin
Chemo- and Dietary Prevention of Familial Cancer: From Theory to Practice	295	(8)
Arthur Schatzkin
Alisa Goldstein
Ernest Hawk
Protocol Concept: Phase I-II Multiple-Dose Safety and Efficacy Clinical Study of Nonsteroidal Anti-Inflammatory/COX-2 Based Regimen in Hereditary Nonpolyposis Colorectal Cancer (HNPCC) Patients and Asymptomatic Carriers	303	(12)
Patrick M. Lynch
The Impact of Living With Hereditary Colorectal Disease	315	(6)
Theresa Berk
Familial Colorectal Cancer in India: The Tata Memorial Hospital Experience	321	(8)
K.M. Mohandas
Gene-Diet Interactions and the High Colorectal Cancer Risk of Japanese Americans	329	(8)
Loic Le Marchandd
Lakshmi Sivaraman
Adrian A. Franke
Lisa M. Pierce
Ann Seifried
Annette Lum
Laurie J. Custer
Pratibha V. Nerurkar
Impact of Migration on the Phenotypes of Familial Cancer Clusters: A Study of Japanese Americans	337	(6)
Grant N. Stemmermann
A.M.Y. Nomura
J. Lee
PART 3B OTHER GASTROINTESTINAL CANCERS	343	(26)
Mutagen Sensitivity as a Predisposing Factor in the Identification of High-Risk Individuals in Oral Cancer Families	345	(8)
Ravindran Ankathil
Dinesh Roy
B. Vinod Kumar
G. Sunil Nayar
B. Jyothish
R. Chandini
F. Joseph
M. Krishnan Nair
Genetic Alterations in Esophageal Cancers	353	(8)
R. Montesano
C. Barnas
P. Taniere
T. Henn
O.A. Haas
P. Hainaut
Identification and Characterization of Families With Aggregation of Gastric Cancer	361	(2)
Atsushi Sasaki
Kazuya Shinmura
Haruhiko Sugimura
Naohito Yamaguchi
Jun Yokota
Ecogenetics of Pancreatic Cancer: A Registry of Cancer Families	363	(6)
John J. Mulvihill
Andrew Shapiro
Jason G. Emmick
Kerry E. Crowley
Carina J. Rodriguez
Michael G. Banke
Patrick L. McNamara
Sidney D. Finkelstein
Mohamed A. Virji
Christopher E. Aston
PART 3C ENDOCRINE CANCERS	369	(30)
Nationwide Survey and Analysis of the RET Proto-oncogene in Inherited Medullary Thyroid Carcinoma in Japan	371	(6)
Hiroshi Takami
Management of Hereditary Medullary Thyroid Carcinoma	377	(8)
Jeffrey F. Moley
Samuel A. Wells Jr.
Consequences of Specific RET Gene Mutations in Families With Multiple Endocrine Neoplasia Type 2	385	(8)
C.J.M. Lips
A.M.J. Moers
R.M. Landsvater
C. Schaap
G.H. Blijham
J.W.M. Hoppener
Th.M. Vroom
J.K. Ploos van Amstel
Recurrent Loss of Heterozygosity for Chromosome 1p in Siblings With Neuroblastoma	393	(6)
Gian Paolo Tonini
Achille Iolascon
Lucia Giordani
Katia Mazzocco
Bruno De Bernardi
Luisa Massimo
Massimo Conte
Giovanna Riccipetitoni
Crocifissa Lo Cunsolo
PART 3D BREAST CANCER	399	(48)
Recent Developments in the Genetic Epidemiology of Breast Cancer	401	(4)
Douglas Easton
Mutation Analysis of the BRCA1 and BRCA2 Genes in Japanese Breast Cancer Families	405	(4)
Yoshio Miki
Toyomasa Katagiri
Yusuke Nakamura
Mapping of Non-BRCA1/2 Breast Cancer Genes	409	(4)
Yin Yao Shugart
Dawn Teare
Carole Cour
Helene Renard
Colette Bonnardel
Alexandre Sibert
Douglas Easton
David Goldgar
Cancer Risk-Modifying Factors in BRCA1 or BRCA2 Mutation Carriers	413	(6)
Timothy R. Rebbeck
BRCA1-Associated Breast Cancer: Clinical, Morphological, and Molecular Features	419	(6)
Hagay Sobol
Dominique Stoppa-Lyonnet
Jean-Marc Guinebretiere
Brigitte Bressac-de Paillerets
Jean-Philippe Peyrat
Michel Longy
Jocelyne Jacquemier
Francois Eisinger
Daniel Birnbaum
A Novel 150K Marker for Early Human Mammary Carcinoma	425	(6)
Max M. Burger
Felix Bachmann
Rahel Banziger
Endocrine Approaches to Breast Cancer Prevention	431	(10)
Anthony Howell
Maria D. Bramley
Robert B. Clarke
Andrew D. Baildam
Elizabeth Anderson
Hereditary Breast Cancer: DNA-Based Genetic Counseling	441	(6)
Jane F. Lynch
Stephen J. Lemon
Carolyn Durham
Carrie Snyder
Patricia Tonin
Gilbert Lenoir
Olga Serova
Steven Narod
Caryn Lerman
Henry T. Lynch
PART 3E GENES FOR OTHER CANCERS	447	(76)
Diverse Cancers in Genetic Disorders: Case Series Compared	449	(6)
Robert W. Miller
Progress in the Diagnosis and Management of Neurofibromatosis	455	(6)
Bruce R. Korf
The NF2 Tumor Suppressor Gene	461	(6)
Brigitte Deguen
Marco Giovanni
Michiko Niwa-Kawiatika
Estelle Brault
Laurence Goutebroze
Gilles Thomas
Tuberous Sclerosis	467	(8)
David J. Kwiatkowski
Cancer Genetics of the Tuberous Sclerosis (TSC2) Gene Mutant	475	(6)
Okio Hino
Toshiyuki Kobayashi
Kenji Orimoto
Shinji Urakami
Tomokazu Fukuda
Nobuo Satake
Yokihiko Yamashita
Dilemmas in Predictive Gene Testing in Li-Fraumeni Syndrome: Experience with a Large Kindred	481	(4)
Robert J. McKinlay Gardner
Mary-Anne Young
Peter G. Bardy
Keith A. Byron
Genetic Studies of Retinoblastoma in India	485	(8)
I.C. Verma
V. Sharma
T.S. Sarkar
M. Kabra
L.S. Arya
N.A. Manjunath
Genetics Update: Cutaneous Malignant Melanoma and Melanocytic Nevi	493	(8)
Mark H. Greene
Xeroderma Pigmentosum: Diagnosis, Registration, and Skin Cancer Prevention	501	(6)
Kenneth H. Kraemer
Werner Syndrome: Adult Progeria With Cancer-Prone Inheritance	507	(8)
Makoto Goto
Yuichi Ishikawa
Haruo Sugano
Yasuhiro Furuichi
Robert W. Miller
Hereditary Multiple Exostoses and Cancer Risk	515	(8)
Daniel E. Porter
A.H.R.W. Simpson
PART 4 WORKSHOP REPORTS	523	(10)
UICC Molecular Biology Workshop Report	525	(6)
Rodney J. Scott
Workshop Report 1	531	(2)
Curtis C. Harris
PART 5 POSTER SESSIONS	533