Fatal Attractions

by Lee, V. M. Y.; Trojanowski, J.; Buee, L.; Christen, Y.

• ISBN13: 9783540671725
• ISBN10: 3540671722
• Format: Hardcover
• Copyright: 2000-07-01
• Publisher: Springer Verlag

Summary

In this volume are contributions based on a meeting arranged by the WHO and the Fondation IPSEN. The scientists focus on neurodegenerative disorders like Alzheimer's Disease, Chromosome 17-Linked Dementia, Parkinson's Disease and disorders with tauopathies.

Table of Contents

The Role of α-Synuclein in Parkinson's Disease: A Biophysical Analogy to Aβ and Alzheimer's Disease	1	(10)
P. T. Lansbury, Jr.
Purification of Lewy Bodies and Identification of α - Synuclein as a major Component of Lewy Bodies	11	(8)
T. Iwatsubo
M. Baba
V. M.-Y Lee
J. Q. Trojanowski
Mutational Analysis of Tau in Chromosome 17-Linked Dementia	19	(10)
K. C. Wilhelmsen
L. N. Clark
D. H.Geshwind
B. L. Miller
Missense and Splice Site Mutations is Tau Associated with FTDP-17: Multiple Pathogenic Mechanisms	29	(24)
M. Hutton
S. Lovestone
P. Heutink
S. Pickering-Brown
S.-H. Yen
Tau Mutations: Genetics and Pathogenetic Mechanisms	53	(13)
P. Poorkaj
I. D'Souza
T. D.Bird
G. D. Schellenberg
Tauopathies and α-Synucleinopathies	66	(21)
M. Goedert
M. G. Spillantini
Distinct Tau Gene Mutations Induce Specific Dysfunction/Toxic Properties in Tau Proteins Associated with Specific FTDP-17 Phenotypes	87	(18)
V. M.-Y.Lee
J.Q.Trojanowski
Neurodegenerative Disorders with Tauopathies: mad Tau Disease?	105	(22)
L. Buee
C. Mailliot
T. Bussiere
N. Sergeant
V. Buee-Scherrer
P. R. Hof
S. Flament
A. Delacourte
Tau Protein: Role in Intracellular Traffic and Development of Cell Polarity	127	(12)
E.-M. Manedelkov
J. Biernat
A. Ebneth
K. Stamer
R. Godemann
B. Trinczek
E. Mandelkov
Subject Index	139