Fluorinated Heterocyclic Compounds : Synthesis, Chemistry, and Applications

by Viacheslav A. Petrov

• ISBN13: 9780470528945
• ISBN10: 047052894X
• Format: eBook
• Copyright: 2009-09-01
• Publisher: Wiley

Summary

A thorough survey of synthetic methods, chemistry, and applications of major classes of fluorinated heterocycles Merging organic, heterocyclic, and fluoroorganic chemistry, fluorinated heterocyclic compounds have distinctively desirable properties suitable for use in pharmaceuticals and agrichemicals, especially their ability to penetrate the cell membrane barrier for drug absorption. Offering a needed overview of this relatively new addition to the heterocyclic family, this essential reference provides the latest state-of-the-art information on key application areas within fluorine chemistry. With contributions from experts from both industry and academia, the book covers the chemistry, synthesis, and applications of fluorinated heterocycles with chapters on: Three-, four-, five-, six-, and seven-membered fluorine-containing heterocycles Fluorinated nucleosides Fluorointermediates Applications of fluorinated heterocycles in agricultural products Pharmaceuticals containing fluorinated heterocycles Technical applications of fluorinated heterocycles Written by a team of world-recognized experts in the area of organic and industrial chemistry of fluorine, Fluorinated Heterocyclic Compounds: Synthesis, Chemistry, and Applications will prove valuable to both students and researchers from academia and industry seeking further knowledge of the synthetic methods, chemistry, and applications of major classes of fluorinated heterocycles.

Table of Contents

Preface

Nomenclature of Polyfluorinated Heterocycles

Synthesis And Chemistry Of Fluorinated Heterocycles

Fluorinated Three-Membered Ring Heterocycles

Fluorinated Four-Membered Heterocycles

Fluorinated Five-Membered Nitrogen-Containing Heterocycles

Fluorinated Five-Membered Heterocycles Containing Oxygen, Sulfur, Selenium and Phosphorus

Synthesis of Fluorinated Sugars from Fluorine-Containing Synthons

Synthesis of Ring Fluorinated Pyridines

Synthesis and Chemical Transformation of Six-Membered Aromatic Heterocycles Containing Perfluoroalkyl Groups

Perfluorinated Six-Membered Aromatic Heterocycles Containing One or More Heteroatom

Perfluorinated Nonaromatic Heterocycles

Seven-Membered and Large Ring Fluorinated Heterocycles

Application Of Fluorinated Heterocyclic Materials

Agricultural Products Based on Fluorinated Heterocyclic Compounds

Pharmaceuticals Containing Fluorinated Heterocyclic compounds

Practical Uses of Flurinated Heterocycles

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