Frontal Lobe Function and Dysfunction

by Levin, Harvey S.; Eisenberg, Howard M.; Benton, Arthur L.

• ISBN13: 9780195062847
• ISBN10: 0195062841
• Format: Hardcover
• Copyright: 1991-11-14
• Publisher: Oxford University Press

Summary

The cognitive and behavioral functions of the frontal lobes have been of great interest to neuroscientists, neurologists, psychologists and psychiatrists. Recent technical advances have made it possible to trace their neuroanatomical connections more precisely and to conduct evoked potentialand neuroimaging studies in patients. This book presents a broad and authoritative synthesis of research progress in this field. It encompasses neuroanatomical studies; experiments involving temporal organization and working memory tasks in non-human primates; clinical studies of patients followingfrontal lobe excisions for intractable epilepsy; metabolic imaging in schizophrenia and affective disorder; neurobehavioral studies of patients with dementia, frontal lobe tumors, and head injuries; magnetic resonance imaging methods for studying human frontal lobe anatomy; theoretical approaches todescribing frontal lobe functions; and rehabilitation of patients with frontal lobe damage including their core problem of diminished awareness. Written by a distinguished group of neuroscientists, psychologists and clinicians, Frontal Lobe Function and Dysfunction provides the best current sourceof information on this region of the brain and its role in cognition, behavior and clinical disorders.

Table of Contents

Contributors	xiii
I INTRODUCTION AND HISTORICAL PERSPECTIVE
The Prefrontal Region: Its Early History	3	(32)
Arthur L. Benton
II NEUROANATOMIC ORGANIZATION, EXPERIMENTAL MODELS, AND NEUROIMAGING IN ANIMALS
Patterns of Connections of the Prefrontal Cortex in the Rhesus Monkey Associated with Cortical Architecture	35	(24)
Helen Barbas
Deepak N. Pandya
Role of Prefrontal Cortex in Delay Tasks: Evidence from Reversible Lesion and Unit Recording in the Monkey	59	(13)
Joaquin M. Fuster
The Circuitry of Working Memory Revealed by Anatomy and Metabolic Imaging	72	(20)
Patricia S. Goldman-Rakic
Harriet R. Friedman
Neuroanatomy of Frontal Lobe In Vivo: A Comment on Methodology	92	(33)
Hanna C. Damasio
III COGNITIVE FUNCTIONING IN PATIENTS WITH FRONTAL LOBE LESIONS
Higher-Order Cognitive Impairments and Frontal Lobe Lesions in Man	125	(14)
Tim Shallice
Paul Burgess
Evoked Potential Studies of Attention Capacity in Human Frontal Lobe Lesions	139	(18)
Robert T. Knight
IV THE ROLE OF THE FRONTAL LOBES IN MEMORY
Interference Effects on Memory Function in Postleukotomy Patients: An Attentional Perspective	157	(16)
Donald T. Stuss
What Is the Role of Frontal Lobe Damage in Memory Disorders?	173	(26)
Arthur P. Shimamura
Jeri S. Janowsky
Larry R. Squire
V RESPONSE PREPARATION AND MOTOR FUNCTIONING
Intentional Motor Disorders	199	(18)
Kenneth M. Heilman
Robert T. Watson
VI INTEGRATION OF EXPERIMENTAL MODELS WITH STUDIES OF PATIENTS
Somatic Markers and the Guidance of Behavior: Theory and Preliminary Testing	217	(13)
Antonio R. Damasio
Daniel Tranel
Hanna C. Damasio
Delayed-Response Tasks: Parallels Between Experimental Ablation Studies and Findings in Patients with Frontal Lesions	230	(26)
Marlene Oscar-Berman
Patrick McNamara
Morris Freedman
Learning Impairments Following Excisions of the Primate Frontal Cortex	256	(19)
Michael Petrides
VII NEUROPSYCHIATRIC AND DEVELOPMENTAL EFFECTS OF FRONTAL LOBE DAMAGE
Prefrontal Cortex Dysfunction in Schizophrenia	275	(13)
Daniel R. Weinberger
Karen Faith Berman
Daniel G. Daniel
The Role of the Frontal Lobes in Affective Disorder Following Stroke	288	(16)
Sergio E. Starkstein
Robert G. Robinson
Dementia of the Frontal Lobe Type	304	(14)
David Neary
Julie S. Snowden
The Contribution of Frontal Lobe Lesions to the Neurobehavioral Outcome of Closed Head Injury	318	(21)
Harvey S. Levin
Felicia C. Goldstein
David H. Williams
Howard M. Eisenberg
Guidelines for the Study of Brain-Behavior Relationships During Development	339	(42)
Adele Diamond
VIII REHABILITATION OF THE FRONTAL LOBE DAMAGED PATIENT
The Relationship of Frontal Lobe Damage to Diminished Awareness: Studies in Rehabilitation	381	(20)
George P. Prigatano
IX EPILOGUE
Concluding Comments	401	(8)
Antonio R. Damasio
Index	409