Frontiers of Cord Blood Science

by Bhattacharya, Niranjan; Stubblefield, Phillip G.

• ISBN13: 9781848001664
• ISBN10: 1848001665
• Edition: 1st
• Format: Hardcover
• Copyright: 2009-02-28
• Publisher: Springer Verlag

Summary

Since the first successful transplantation of umbilical cord blood in 1988, cord blood has become an important source of hematopoietic stem and progenitor cells for the treatment of blood and genetic disorders. Significant progress has been accompanied by challenges for scientists, ethicists, and health policy makers. With the recognition of the need for a national system for the collection, banking, distribution, and use of cord blood and the increasing focus on cord blood as an alternative to embryos as a source of tissue for regenerative medicine, it has garnered significant attention recently.

Table of Contents

Umbilical Cord Blood Stem Cell (Basic Science)
Placental and Pregnancy Stem Cells	p. 3
Cord Blood Stem Cells - The Basic Science	p. 19
Stem Cells from Umbilical Cord Blood	p. 27
Ex Vivo Expansion of Cord Blood	p. 91
Mesenchymal Stem Cells: Applications in Cell and Gene Therapy	p. 97
Non-hematopoietic Stem and Progenitor Cells Derived From Human Umbilical Cord Blood	p. 123
Umbilical Cord Blood Stem Cell Transplantation
Cord Blood Transplantation for Pediatric Non-Malignant Conditions	p. 161
Cord Blood Transplantation for Hematologic Malignancies	p. 195
Double Umbilical Cord Blood Transplantation in Adults	p. 209
Transfusion of Cord Blood
Placental Umbilical Cord Whole Blood Transfusion: A True Blood Substitute to Combat Anemia in the Background of Chronic Disease - A Study Report (1999-2006)	p. 227
Umbilical Cord Blood Therapy in Neurology	p. 265
Cord Blood: Opportunities and Challenges for the Reconstructive Surgeon	p. 273
Umbilical Cord Blood Transfusion - A Clinical Overview	p. 289
Cord Blood Stem Cell Banking
Establishment of the UK Stem Cell Bank and Its Role in Stem Cell Science	p. 299
Cord Blood Allogeneic and Autologous Banking	p. 307
Potential Engineering Application of Cord Blood
Possibilities of Using Cord Blood for Improving the Biocompatibility of Implants	p. 319
Potential of Stem Cell to Tailor the Bone-Ceramic Interface for Better Fixation of Orthopedic Implants	p. 331
Ethics
Some Aspects of the Ethics of Stem Cell Research	p. 361
Index	p. 369
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