Functional Biochemistry in Health and Disease

by Newsholme, Eric; Leech, Anthony

• ISBN13: 9780471988205
• ISBN10: 0471988200
• Edition: 2nd
• Format: Hardcover
• Copyright: 2010-06-14
• Publisher: Wiley

Summary

This text provides a clear and straightforward account of the biochemistry that is necessary to understand the physiological functions of tissues or organs essential to the life of human beings. Focusing on the dynamic aspects of biochemistry and its application to the basic functions of the body, the book bridges the gap between biochemistry and medical practice.Carefully structured within five sections, each biochemical, physiological or medical subject that is covered in the book is presented in one complete chapter. Consequently, each subject can be read and studied in isolation although cross-sectional links between the subjects are included where necessary. Background material, both biochemical and medical, that is necessary for an understanding of the subject, is included at the start of each chapter and clear, simple but relevant diagrams enhance students' understanding. Focuses on medically relevant aspects of biochemistry written from a physiological rather than a molecular perspective Clear presentation that minimises the use of jargon Each chapter contains boxes on related topics, relevant diagrams and a brief glossary Coverage includes athletic performance, cell growth and the immune system Key historical developments are included to show how modern biochemistry has evolvedBy linking biochemistry, medical education and clinical practice this book proves invaluable to students in medical and health sciences, biomedical science and human biology. In addition it is of interest to biochemistry and biology students interested in clinical applications of biochemistry.

Author Biography

Eric Newsholme, Merton College and Department of Biochemistry, University of Oxford, UK.
Tony Leech, Gresham's School, Norfolk, UK Editorial Assistant Mary Board

Table of Contents

Preface

Introduction

A biochemical hierarchy: from the cell to its Human

Essential Topics In Biochemistry, Physiology And Biology

Energy: in the body, tissues and biochemical processes

Enzymes: their properties, regulation and physiology

Transport into the body: the gastrointestinal tract, digestion and absorption

Transport: into the cell

Essential Metabolism

Carbohydrate metabolism

Fat metabolism

Amino acid and protein metabolism

Oxidation of fuels and ATP generation

Metabolism of Ammonia: degradation of nucleotides; the ornithine cycle

Synthesis of fats, fatty messengers and cholesterol

Hormones: chemical communication

Essential Processes Of Life

Physical activity: in non-athletes, athletes and patients

Acid/Base balance in normal and pathological states

Mental activity and mental illness

Nutrition

Starvation

Mechanisms of defence: barriers, enzymes and the immune system

Trauma

Sexual reproduction

Common Clinical Problems And Diseases

Growth of cells and the skeleton

Atherosclerosis, hypertension and myocardial infarction

Cancer

Eating disorders: anorexia nervosa and bulimia nervosa

Obesity and adipose tissue

Lipoprotein metabolism and dyslipoproteinaemias

Table of Contents provided by Publisher. All Rights Reserved.