Gaba in the Nervous System: The View at Fifty Years

by Martin, David L.; Olsen, Richard W.

• ISBN13: 9780781722674
• ISBN10: 0781722675
• Format: Hardcover
• Copyright: 2000-09-01
• Publisher: Lippincott Williams & Wilkins

Summary

New York State Department of Health, Albany. Provides a broad overview of the current state of GABA research, and when possible, places this work in its historical context. Includes extensive references and halftone illustrations. For researchers. DNLM: GABA--Physiology.

Table of Contents

Contributing Authors	vii
Preface	xiii
Adventures with GABA: Fifty Years On	1	(24)
Eugene Roberts
Mechanisms Controlling GABA Synthesis and Degradation in the Brain	25	(18)
David L. Martin
Allan J. Tobin
Cytoplasmic Membrane Transporters for GABA	43	(8)
Baruch I. Kanner
Uptake and Storage of GABA in Synaptic Vesicles	51	(14)
Erode Fonnum
Else Marie Fykse
GABA Chemistry: Analogs of GABA as Therapeutic and Investigational Agents	65	(16)
Graham A. R. Johnston
Function of GABAA Receptors: Insights from Mutant and Knockout Mice	81	(16)
Richard W. Olsen
Gregg F. Homanics
The Benzodiazepine Site of GABAA Receptors	97	(16)
Hanns Mohler
Dietmar Benke
J. M. Fritschy
J. Benson
Pharmacologic Subtypes of GABAA Receptors Based on Subunit Composition	113	(14)
Paul J. Whiting
Keith A. Wafford
Ruth M. McKernan
Functional Domains of GABA Receptors	127	(14)
Yongchang Chang
David S. Weiss
Kinetic Properties of GABAA Receptor Channels	141	(26)
Robert L. Macdonald
Kevin F. Haas
Alcohol and General Anesthetic Actions on the GABAA Receptor	167	(24)
Neil L. Harrison
Matthew D. Krasowski
R. Adron Harris
Regulation of GABAA Receptors by Protein Phosphorylation	191	(16)
Nicholas J. Brandon
Thevor C. Smart
Stephen J. Moss
Neurosteroids and GABAA Receptor Plasticity	207	(26)
Giovanni Biggio
Maria Luisa Barbaccia
Paolo Follesa
Mariangela Serra
Robert H. Purdy
Alessandra Concas
GABAB Receptors: Structure and Function	233	(12)
Norman C. Bowery
GABA Emerges as a Developmental Signal during Neurogenesis of the Rat Central Nervous System	245	(20)
Jeffery L. Barker
Toby Nan Behar
Wu Ma
Dragon Maric
Irina Maric
GABA in the Basal Ganglia	265	(28)
Jean-Jacques Soghomonian
Marie-Francoise Chesselet
Epilepsy	293	(24)
Massimo Avoli
GABAergic Interneuronal Networks in the Hippocampus	317	(20)
Gyorgy Buzsaki
George Dragoi
Jozsef Csicsvari
Hajime Hirase
Andras Czurko
Darrell A. Henze
GABA Neurons of the Hippocampal Formation: Localization, Vulnerability, and Plasticity	337	(20)
Carolyn R. Houser
Monique Esclapez
Nianhui Zhang
GABA Neurons in the Neoeortex	357	(12)
Charles E. Ribak
Xiao-Xin Yan
GABAA Receptor Diversity: A View from the Cerebellum	369	(14)
Daniela Merlo
Stephen C. Brickley
Mark Farrant
Stuart G. Cull-Candy
William Wisden
GABAergic Inhibition in the Cerebellar System	383	(26)
Enrico Mugnaini
Neuromodulation of GABA in Developing and Mature Hypothalamic Neurons	409	(30)
Anthony N. van den Pol
Karl Obrietan
GABA in the Mammalian Spinal Cord	439	(20)
Andrew J. Todd
David J. Maxwell
GABA in the Retina	459	(12)
Dianna A. Johnson
The Role of Glutamic Acid Decarboxylase and GABA in the Pancreas and Diabetes	471	(14)
Steven D. Chessler
Ake Lernmark
Subject Index	485