Gastrointestinal Transit

by Kramm, Michael A.; Lennard-Jones, John E.; Kamm, Michael A.

• ISBN13: 9781871816112
• ISBN10: 1871816114
• Format: Hardcover
• Copyright: 1991-01-01
• Publisher: Routledge

Table of Contents

Contributors
Foreword
Preface
Acknowledgements
Physiological Control of Gastrointestinal Transit
Cerebral and Spinal Control of Gastrointestinal Motor Functions	p. 3
Extrinsic Autonomic Control of Human Gastrointestinal Transit	p. 13
Enteric Nervous System: Neural Connections, Neurotransmitters, and the Function of 5-Hydroxytryptamine	p. 21
Circulating Hormonal Control	p. 33
Motor Physiology
An Overview of the Physiology of Gastric Motility	p. 47
The Small Intestine and the Ileal Brake	p. 55
Motor Physiology of the Human Colon	p. 65
Measurement of Transit
Measurement of Transit - Oesophagus and Stomach	p. 79
Measurement of Small Bowel Transit in Humans	p. 97
Measurement of Colonic Transit	p. 109
Clinical Disorders of Transit and their Treatment
Clinical disorders of Oesophageal Transit and Gastric Emptying	p. 121
Constipation	p. 133
Diarrhoea	p. 141
Chronic Intestinal Pseudo-obstruction	p. 157
Pharmacology of Substances which Influence Transit
Pharmacotherapy of Gastrointestinal Transit	p. 171
Prokinetic Substituted Benzamides - in vitro Studies on their Mechanism of Action	p. 179
Mechanisms of Action of Laxatives	p. 187
Effects of Long-term Treatment with Senna on Neuromuscular Transmission in the Large Intestine of the Rat	p. 195
Fibre and Bulk Preparations	p. 209
Antidiarrhoeal Drugs	p. 219
Drugs Acting on Potassium or Calcium Channels: Effects on Gastrointestinal Motility	p. 231
The Clinical Problem
Correlation of Symptoms, Measurements and Treatment	p. 245
Index	p. 251
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