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Note: Supplemental materials are not guaranteed with Rental or Used book purchases.
Purchase Benefits
What is included with this book?
An up-to-date and complete treatment of the strategies, designs and analysis methods for studying complex genetic disease in human beings
In the newly revised Third Edition of Genetic Analysis of Complex Diseases, a team of distinguished geneticists delivers a comprehensive introduction to the most relevant strategies, designs and methods of analysis for the study of complex genetic disease in humans. The book focuses on concepts and designs, thereby offering readers a broad understanding of common problems and solutions in the field based on successful applications in the design and execution of genetic studies.
This edited volume contains contributions from some of the leading voices in the area and presents new chapters on high-throughput genomic sequencing, copy-number variant analysis and epigenetic studies. Providing clear and easily referenced overviews of the considerations involved in genetic analysis of complex human genetic disease, including sampling, design, data collection, linkage and association studies and social, legal and ethical issues.
Genetic Analysis of Complex Diseases also provides:
This latest edition of Genetic Analysis of Complex Diseases is a must-read resource for molecular biologists, human geneticists, genetic epidemiologists and pharmaceutical researchers. It is also invaluable for graduate students taking courses in statistical genetics or genetic epidemiology.
William K. Scott, PhD, is Professor at the University of Miami Leonard M. Miller School of Medicine where he teaches design and analysis of human genomic studies. He has authored over 200 peer-reviewed articles on the genetic epidemiology of complex traits.
Marylyn D. Ritchie, PhD, is Professor in the Department of Genetics at the University of Pennsylvania, Perelman School of Medicine. She is also the Director of the Center for Translational Bioinformatics in the Institute for Biomedical Informatics. She has authored over 350 peer-reviewed articles on statistical genetics, translational bioinformatics, and biomedical informatics.
1. Designing A Study For Identifying Genes In Complex TraitsWilliam K. Scott, Marylyn D. Ritchie, Jonathan L. Haines, and Margaret A. Pericak-Vance
2. Basic Concepts In GeneticsKayla Fourzali, Abigail Deppen, and Elizabeth Heise
3. Defining Disease PhenotypesC. Hung and O. Bodamer
4. Determining The Genetic Component of A DiseaseAllison Ashley Koch and Evadnie Rampersaud
5. Study Design For Genetic StudiesDana C Crawford and Logan Dumitrescu
6. Responsible Conduct of Research In Genetic StudiesSusan Estabrooks Hahn, Adam Buchanan, and Susan H. Blanton
7. Linkage AnalysisSusan Blanton
8. Data ManagementStephen D. Turner and William S. Bush
9. Linkage Disequilibrium and Association AnalysisEden R. Martin and Ren-Hua Chung
10. Genome-Wide Association StudiesJacob McCauley, Yogasudha Veturi, Shefali Setia Verma, and Marylyn D. Ritchie
11. Bioinformatics of Human Genetic Disease StudiesDale J. Hedges
12. Complex Genetic Interactions / Data Mining/ Dimensionality ReductionWilliam S. Bush and Stephen D. Turner
13. Sample Size, Power, and Data SimulationSARAH A. PENDERGRASS, YI-JU LI, SUSAN SHAO, MARYLYN D. RITCHIE
Index
The New copy of this book will include any supplemental materials advertised. Please check the title of the book to determine if it should include any access cards, study guides, lab manuals, CDs, etc.
The Used, Rental and eBook copies of this book are not guaranteed to include any supplemental materials. Typically, only the book itself is included. This is true even if the title states it includes any access cards, study guides, lab manuals, CDs, etc.