Genetics: From Genes to Genomes

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  • Edition: 2nd
  • Format: Hardcover
  • Copyright: 2003-03-04
  • Publisher: McGraw-Hill Science/Engineering/Math
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Genetics: From Genes to Genomes is a cutting-edge, introductory genetics text authored by an unparalleled author team, including Nobel Prize winner, Leland Hartwell. The Second Edition continues to build upon the integration of Mendelian and molecular principles, providing students with the links between early genetics understanding and the new molecular discoveries that have changed the way the field of genetics is viewed.

Table of Contents

1 Genetics: The Study of Biological Information

Part 1 Basic Principles: How Traits Are Transmitted

2 Mendel's Breakthrough: Patterns, Particles, and Principles of Heredity

3 Extensions to Mendel: Complexities in Relating Genotype to Phenotype

4 The Chromosome Theory of Inheritance

5 Linkage, Recombination, and the Mapping of Genes on Chromosomes

Part 2 What Genes Are and What They Do

6 DNA: How the Molecule of Heredity Carries, Replicates, and Recombines Information

7 Anatomy and Function of a Gene: Dissection Through Mutation

8 Gene Expression: The Flow of Genetic Information from DNA via RNA to Protein

Part 3 Genomes

9 Deconstructing the Genome: DNA at High Resolution

10 Reconstructing the Genome Through Genetic and Molecular Analysis

11 The Direct Detection of Genotype Distinguishes Individual Genomes

Part 4 How Genes Travel

12 The Eukaryotic Chromosome: An Organelle for Packaging and Managing DNA

13 Chromosomal Rearrangements and Changes in Chromosome Number Reshape Eukaryotic Genomes

14 The Prokaryotic Chromosome: Genetic Analysis in Bacteria

15 The Chromosomes of Organelles Outside the Nucleus Exhibit Non-Mendelian Patterns of Inheritance

Part 5 How Genes Are Regulated

16 Gene Regulation in Prokaryotes

17 Gene Regulation in Eukaryotes

18 Cell-Cycle Regulation and the Genetics of Cancer

19 Using Genetics to Study Development

Part 6 How Genes Change

20 The Genetic Analysis of Populations and How They Evolve

21 Evolution at the Molecular Level

Reference: Portraits of Model Eukaryotic Organisms

A Saccharomyces cerevisiae: Genetic Portrait of Yeast
B Arabidopsis thaliana: Genetic Portrait of a Model Plant
C Caenorhabditis elegans: Genetic Portrait of a Simple Multicellular Organism
D Drosophila melanogaster: Genetic Portrait of the Fruit Fly
E Mus musculus: Genetic Portrait of the House Mouse

Guidelines for Gene Nomenclature

Brief Answer Section

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