Genetics for Health Professionals in Cancer Care From Principles to Practice

by Jacobs, Chris; Robinson, Lorraine; Webb, Patricia

• ISBN13: 9780199672844
• ISBN10: 0199672849
• Edition: 1st
• Format: Paperback
• Copyright: 2014-10-07
• Publisher: Oxford University Press

Summary

The role of genetics is becoming increasingly important in all aspects of healthcare and particularly in the field of cancer care. Genetics for Health Professionals in Cancer Care: From Principles to Practice equips health professionals with the knowledge and skills required for all aspects of managing cancer family history. This includes taking an accurate cancer family history and drawing a family tree; understanding cancer biology, basic cancer genetics and the genes involved in hereditary breast, ovarian, prostate, colorectal, gastric and related gynaecological cancers and rare cancer predisposing syndromes; assessing cancer risk and communicating risk information; early detection and risk reducing measures available for those at increased risk and managing individuals with hereditary cancer.

Drawing on experiences of health professionals, Genetics for Health Professionals in Cancer Care discusses the challenges raised and provides practical advice and insight into what happens when a patient is referred for genetic counselling and genetic testing, including the psychological, social and ethical issues faced by individuals and families with and at risk of hereditary cancer. The book also provides practical guidance on setting up a cancer family history clinic in primary and secondary care.

Genetics for Health Professionals in Cancer Care is essential reading for healthcare professionals working with cancer patients and their families, and is an ideal reference text for non-specialists working in cancer genetics.

Author Biography

Chris Jacobs, NIHR Doctoral Research Fellow, University College London and Consultant Genetic Counsellor in Cancer Genetics, Department of Clinical Genetics, Guy's Hospital, London, UK,Lorraine Robinson, Principal Lecturer and Programme Leader, Department of Adult Nursing, King's College London, UK,Patricia Webb, Principal Lecturer and Course Director Dip/BSc.Health Care Practice, Faculty of Health and Social Care Sciences, St. George's University of London, UK

Prior to becoming a genetic counsellor, Chris was an experienced critical care nurse and transplant coordinator. She was appointed to the post of Consultant Genetic Counsellor in Cancer Genetics in 2006 and has led/ jointly led the cancer genetics service for the South East of England since 2008. In addition to providing genetic counselling, her service development experience has included setting up and establishing a network of cancer risk assessment clinics and establishing and running a BRCA family service for patients with BRCA1/2 gene mutations and developing, implementing a rapid breast cancer risk assessment service and Mismatch Repair gene testing service. Her educational and research interests are in improving communication and understanding about cancer genetics. Chris is the clinical lead for the Advanced Healthcare Practice in Cancer Genetics course, run jointly by King's College London and St. George's University of London and Kingston University.

Lorraine Robinson has worked as a Lecturer for several years both at King's College London and The Royal Marsden Hospital. Her interests are in cancer care, breast care, psychological interventions and health policy. She has worked as an Associate Journal Editor and has had key positions within the RCN Cancer Nursing Society and EONS. Lorraine is undertaking a Doctorate in Healthcare with her research focussing on the needs of women living with metastatic breast cancer. At present Lorraine is the Programme Leader for the BSc programmes in Cancer Care, Palliative Care and Haemato-oncology and the Lead for the pre-registration BSc Adult Nursing course.

Pat Webb is committed to delivering a multi-professional and collaborative approach to cancer and palliative care in clinical work, education and research. In her current role (Principal Lecturer in the Faculty of Health and Social Care Sciences, and Course Director, MSc Healthcare at St. George's University of London), she is the strategic lead in cancer and palliative care research and education, running and developing the curricula for post graduate modules in cancer and End of Life Care. In addition, Pat was the Editor of the international peer-reviewed journal, European Journal of Cancer Care for 18 years until 2009. Pat has used her nursing qualification and experience to work across professional disciplines, and statutory and voluntary sectors. This has included reporting on the ethics of palliative care for the Bioethics division of the European Commission and organizing and lecturing on cancer and palliative care programmes through the European School of Oncology.

Table of Contents

Section 1: Putting cancer genetics into context
1. Putting cancer genetics into context, Chris Jacobs
Section 2: Cancer genetics: the basics
2. Cancer genetics: the basics - Introduction, Chris Jacobs
3. Taking a cancer family history and drawing a family tree, Emma Williams
4. Basic cancer genetics, Christine Patch
5. Cancer biology, Audrey Yandle
6. Cancer genetics: the basics - Summary, Lorraine Robinson and Pat Webb
Section 3: Genetics of specific cancers
7. Genetics of specific cancers - Introduction, Chris Jacobs
8. Genetics of breast and ovarian cancer, Deborah Ruddy
9. Genetics of colorectal, gastric and related gynaecological cancers, Gabriella Pichert
10. Genetics of prostate cancer, Audrey Ardern-Jones, Elizabeth Bancroft and Rosalind Eeles
11. Genetics of rare cancer syndromes, Adam Shaw
12. Genetics of specific cancers - Summary, Pat Webb and Lorraine Robinson
Section 4: Cancer risk assessment and communicating risk
13. Cancer risk assessment and communicating risk - Introduction, Chris Jacobs
14. Breast and ovarian cancer risk assessment, Vishakha Trepathi and Charlotte Eddy
15. Colorectal and gastric and related cancers risk assessment, Sarah Rose and Vicki Keisel
16. Cancer risk assessment and communicating risk - Summary, Lorraine Robinson and Pat Webb
Section 5: Early detection of hereditary cancer
17. Early detection of hereditary cancer - Introduction, Chris Jacobs
18. Early detection of hereditary breast cancer, Michael Michell
19. Early detection of hereditary colorectal and gastric cancer, Abdulkani Yusuf and Kevin John Monahan
20. Early detection of hereditary gynaecological cancers, Aleksandra Gentry-Maharaj and Usha Menon
21. Early detection of hereditary cancer - Summary, Lorraine Robinson and Pat Webb
Section 6: Reducing the risk of cancer
22. Reducing the risk of cancer - Introduction, Chris Jacobs
23. Reducing the risk of breast cancer, Hisham Hamed and Jian Farhadi
24. Reducing the risk of colorectal and gastric cancer, Eric Chung and Mark George
25. Reducing the risk of gynaecological cancers, Adam Rosenthal
26. Reducing the risk of cancer - Summary, Lorraine Robinson and Pat Webb
Section 7: Managing hereditary cancer
27. Managing hereditary cancer - Introduction, Chris Jacobs
28. Managing hereditary breast cancer, Jennifer Glendenning, Ashutosh Kothari, Amanda Shewbridge and Andrew Tutt
29. Managing hereditary colorectal and gastric cancer, Kiruthikah Thillai, Claire Coughlan, Mahmoud Ali Zohree Ali, Paul Ross
30. Managing hereditary gynaecological cancer, Charlotte Moss, Emma Crosbie and Ana Montes
31. Managing hereditary cancer - Summary, Pat Webb and Lorraine Robinson
Section 8: Genetic counselling and supporting individuals with a family history of cancer
32. Genetic counselling and supporting individuals with a family history of cancer - Introduction, Chris Jacobs
33. Genetic counselling about cancer predisposition, Chris Jacobs, Eshika Haque and Gillian Scott
34. Psychosocial issues and supporting individuals with a family history of cancer, Clare Firth
35. Ethical and cultural issues, Athalie Melville and Sally Watts
36. Genetic counselling and supporting individuals with a family history of cancer - Summary, Pat Webb and Lorraine Robinson
Section 9: Managing cancer family history in primary, secondary and palliative care
37. Managing cancer family history in primary, secondary and palliative care - Introduction, Chris Jacobs
38. Experiences of managing cancer family history in primary care, Belinda Lotter and Kati Harris
39. Experiences of managing cancer family history in secondary care, Gillian Bowman and Linda Dyer
40. Experiences of managing cancer family history in palliative care, Sheila Goff
41. A practical guide to setting up a cancer family history clinic in primary and secondary care, Chris Jacobs
42. Managing cancer family history in primary, Secondary and palliative care - Summary, Pat Webb and Lorraine Robinson