Genetics Laboratory Investigations

by Mertens, Thomas R.; Hammersmith, Robert L.

• ISBN13: 9780130193308
• ISBN10: 0130193305
• Additional ISBN(s): 9780131742529
• Edition: 12th
• Format: Paperback
• Copyright: 2001-01-01
• Publisher: Prentice Hall
• More Book Details
• Purchase Benefits

Summary

For lab courses in genetics. THE definitive genetics lab manual and winner of 1998 Textbook Authors Association McGuffey Award in Life Sciences. Genetics Laboratory Investigations, 12/E is user-friendly for both faculty and studentshaving been developed by those actively involved in teaching general genetics. The manual stresses classical genetics, but includes some of the recent advances related to molecular and human genetics.

Table of Contents

Preface	vii
Drosophila and Maize Experiments in Genetics: Monohybrid Crosses	1	(10)
Drosophila and Maize Experiments in Genetics: Dihybrid Crosses	11	(8)
Principles of Probability	19	(8)
The Chi-Square Test	27	(14)
Cell Reproduction: Mitosis	41	(10)
Meiosis in Animals: Oogenesis and Spermatogenesis	51	(8)
Meiosis in Angiosperms: Microsporogenesis and Megasporogenesis	59	(16)
Polytene Chromosomes from Drosophila Salivary Glands	75	(4)
Sex Chromosomes and Gene Transmission	79	(10)
The Sex Check: A Study of Sex Chromatin in Human Cells	89	(6)
Human Chromosomes	95	(26)
Linkage and Crossing Over	121	(20)
Genetics of Ascospore Color in Sordaria: An Investigation of Linkage and Crossing Over Using Tetrad Analysis	141	(8)
Open-Ended Experiments Using Drosophila: Locating a Mutant Gene in Its Chromosome	149	(6)
The Genetic Material: Isolation of DNA	155	(6)
Restriction Endonuclease Digestion and Gel Electrophoresis of DNA	161	(16)
Amplification of DNA Polymorphisms by Polymerase Chain Reaction (PCR) and DNA Fingerprinting	177	(16)
Transformation of E. coli	193	(8)
Gene Action: Synthesis of β-Galactosidase in Escherichia coli	201	(6)
Chromatographic Characterization of Drosophila melanogaster Mutants	207	(6)
Bacterial Mutagenesis	213	(6)
Gene Recombination in Phage	219	(8)
Polygenic Inheritance: Fingerprint Ridge Count	227	(10)
Population Genetics: The Hardy-Weinberg Principle	237	(12)
Population Genetics: The Effects of Selection and Genetic Drift	249	(8)
Applied Human Genetics	257	(16)
Supplemental Laboratory Topics	273	(5)
Plant Speciation by Interspecific Hybridization and Allotetraploidy	273	(2)
Chromosome Translocations in Rhoeo spathacea	275	(1)
Human Pedigree Analysis	276	(2)
Tagging and Amplification of DNA Using DNA Polymerase	278