Germ Cells

by Sassone-Corsi, Paolo; Fuller, Margaret T; Braun, Robert E.

• ISBN13: 9781936113514
• ISBN10: 1936113511
• Edition: 1st
• Format: Hardcover
• Copyright: 2011-09-09
• Publisher: Cold Spring Harbor Laboratory Press

Summary

With the ability to undergo both mitosis and meiosis, germ cells give rise to gametes and serve as the link between generations in sexually reproducing organisms. This collection reviews the biology of germ cells in metazoans, describing the undifferentiated state of germline stem cells, the triggers for meiotic entry, and the transcriptional and posttranscriptional controls that lead to the formation of mature gametes during spermatogenesis and oogenesis.

Table of Contents

Preface	p. vii
Germline Stem Cells	p. 1
Molecular Regulation of the Mitosis/Meiosis Decision in Multicellular Organisms	p. 21
Function of the Sex Chromosomes in Mammalian Fertility	p. 37
Unique Aspects of Transcription Regulation in Male Germ Cells	p. 55
Translational Control in Oocyte Development	p. 71
RNA Granules in Germ Cells	p. 85
Germ Cell Intercellular Bridges	p. 113
Small Noncoding RNAs in the Germline	p. 131
Developmental Control of Oocyte Maturation and Egg Activation in Metazoan Models	p. 147
Mammalian Genomic Imprinting	p. 167
Nuclear Transfer to Eggs and Oocytes	p. 185
Selection in the Rapid Evolution of Gamete Recognition Proteins in Marine Invertebrates	p. 199
Index	p. 217
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