Gram-Positive Pathogens

by Fischetti, Vincent A.; Novick, Richard P.; Ferretti, Joseph J.; Portnoy, Daniel A.; Rood, Julian I.

• ISBN13: 9781555811662
• ISBN10: 1555811663
• Format: Hardcover
• Copyright: 2000-01-01
• Publisher: Amer Society for Microbiology

Summary

Rockefeller Univ., New York City, NY. Discusses the mechanisms of gram-positive bacterial pathogenicity, including the current knowledge on gram-positive structure and mechanisms of antibiotic resistance. Emphasizes streptococci, staphylococci, listeria, and spore-forming pathogens. For researchers. DNLM: Gram-Positive Bacteria.

Table of Contents

Contributors	ix
Preface	xiii
SECTION I THE GRAM-POSITIVE CELL WALL	1	(24)
Vincent A. Fischetti
Ultrastructure of Gram-Positive Cell Walls	3	(8)
Terry J. Beveridge
Surface Proteins on Gram-Positive Bacteria	11	(14)
Vincent A. Fischetti
SECTION II THE STREPTOCOCCUS	25	(282)
Vincent A. Fischetti
Joseph J. Ferretti
A. GROUP A STREPTOCOCCI
Intracellular Invasion by Streptococcus pyogenes: Invasins, Host Receptors, and Relevance to Human Disease	27	(7)
David Cue
Priscilla E. Dombek
P. Patrick Cleary
Capsular Polysaccharide of Group A Streptococcus	34	(9)
Michael R. Wessels
Toxins and Superantigens of Group A Streptococci	43	(10)
John K. McCormick
Patrick M. Schlievert
Genetics of Group A Streptococci	53	(13)
Michael Caparon
Cross-Reactive Antigens of Group A Streptococci	66	(12)
Madeleine W. Cunningham
Extracellular Matrix Interactions with Gram-Positive Pathogens	78	(9)
Gursharan S. Chhatwal
Klaus T. Preissner
Streptococci-Mediated Host Cell Signaling	87	(9)
Vijaykumar Pancholi
Vaccine Approaches To Protect against Group A Streptococcal Pharyngitis	96	(9)
Vincent A. Fischetti
The Bacteriophages of Group A Streptococci	105	(12)
W. Michael McShan
Molecular Epidemiology, Ecology, and Evolution of Group A Streptococci	117	(8)
Debra E. Bessen
Susan K. Hollingshead
B. GROUP B STREPTOCOCCI
Pathogenic Mechanisms and Virulence Factors of Group B Streptococci	125	(12)
Victor Nizet
Craig E. Rubens
Surface Structures of Group B Streptococcus Important in Human Immunity	137	(17)
Lawrence C. Paoletti
Lawrence C. Madoff
Dennis L. Kasper
Epidemiology of Group B Streptococcal Infections	154	(9)
Sharon Balter
Cynthia G. Whitney
Anne Schuchat
C. GROUP C AND G STREPTOCOCCI
Genetics and Pathogenicity Factors of Groups C and G Streptococci	163	(14)
Horst Malke
Pathogenicity Factors in Group C and G Streptococci	177	(7)
Gursharan S. Chhatwal
Susanne R. Talay
Group C and Group G Streptococcal Infections: Epidemiologic and Clinical Aspects	184	(7)
Harold R. Oster
Alan L. Bisno
D. STREPTOCOCCUS PNEUMONIAE
The Cell Wall of Streptococcus Pneumoniae	191	(10)
Alexander Tomasz
Werner Fischer
Streptococcus pneumoniae Capsular Polysaccharide	201	(13)
James C. Paton
Judy K. Morona
Streptococcus pneumoniae: Invasion and Inflammation	214	(11)
Khoosheh Gosink
Elaine Tuomanen
Phase Variation of Streptococcus pneumoniae	225	(7)
Jeffrey N. Weiser
Genetics of Streptococcus pneumoniae	232	(12)
Janet Yother
Pneumococcal Vaccines	244	(7)
D. E. Briles
J. C. Paton
E. Swiatlo
M. H. Nahm
E. ENTEROCOCCI
Pathogenicity of Enterococci	251	(8)
Lynn E. Hancock
Michael S. Gilmore
Enterococcal Genetics	259	(13)
Keith E. Weaver
F. ORAL STREPTOCOCCI
Pathogenesis of Oral Streptococci	272	(8)
R. R. B. Russell
Streptococcus mutans: Molecular Genetic Analysis	280	(7)
Howard K. Kuramitsu
Genetics of Streptococcus sanguis	287	(8)
Howard E. Jenkinson
G. LACTOCOCCI
Genetics of Lactococci	295	(12)
Patrick Duwat
Karin Hammer
Alexandre Bolotin
Alexandra Gruss
SECTION III THE STAPHYLOCOCCUS	307	(164)
Richard P. Novick
Diagnostics, Typing, and Taxonomy	309	(8)
Wolfgang Witte
Genetic and Physical Map of the Chromosome of Staphylococcus aureus 8325	317	(9)
John J. Iandolo
Genetics: Accessory Elements and Genetic Exchange	326	(13)
Neville Firth
Ronald A. Skurray
Carbohydrate Catabolism: Pathways and Regulation	339	(6)
Reinhold Bruckner
Joannis Bassias
Respiration and Small-Colony Variants of Staphylococcus aureus	345	(6)
Richard A. Proctor
The Staphylococcal Cell Wall	351	(10)
Alexander Tomasz
Staphylococcal Capsule	361	(6)
Chia Y. Lee
Jean C. Lee
Staphylococcus aureus Exotoxins	367	(12)
Gregory A. Bohach
Timothy J. Foster
Extracellular Enzymes	379	(7)
Staffan Arvidson
Staphylococcal Surface Proteins	386	(6)
Magnus Hook
Timothy J. Foster
Pathogenicity Factors and Their Regulation	392	(16)
Richard P. Novick
Staphylococcus aureus-Eukaryotic Cell Interactions	408	(6)
Franklin D. Lowy
The Epidemiology of Staphylococcus Infections	414	(8)
Fred C. Tenover
Robert P. Gaynes
Animal Models of Experimental Staphylococcus aureus Infection	422	(9)
L. Vincent Collins
Andrej Tarkowski
Cellular and Extracellular Defenses against Staphylococcal Infections	431	(11)
Jerrold Weiss
Arnold S. Bayer
Michael Yeaman
Biology and Pathogenicity of Staphylococcus epidermidis	442	(8)
Christine Heilmann
Georg Peters
Biology and Pathogenicity of Staphylococci Other than Staphylococcus aureus and Staphylococcus epidermidis	450	(13)
Gerard Lina
Jerome Etienne
Francois Vandenesch
Antibiotic Resistance in the Staphylococci	463	(8)
Steven J. Projan
SECTION IV THE LISTERIA	471	(46)
Daniel A. Portnoy
Epidemiology and Clinical Manifestations of Listeria Monocytogenes Infection	473	(7)
Walter F. Schlech III
Immune and Inflammatory Responses to Listeria monocytogenes Infection	480	(8)
Alyce Finelli
Eric G. Pamer
Genetic Tools for Use with Listeria Monocytogenes	488	(11)
Nancy E. Freitag
Regulation of Virulence Genes in Pathogenic Listeria spp.	499	(8)
Werner Goebel
Jurgen Kreft
Regine Bockmann
The Cell Biology of Invasion and Intracellular Growth by Listeria monocytogenes	507	(10)
Pascale Cossart
Daniel A. Portnoy
SECTION V SPORE-FORMING PATHOGENS AND GRAM-POSITIVE ACTINOMYCETALES	517	(90)
Julian I. Rood
Bacillus anthracis	519	(10)
Theresa M. Koehler
Clostridial Genetics	529	(11)
Dena Lyras
Julian I. Rood
Neurotoxigenic Clostridia	540	(11)
Eric A. Johnson
Enterotoxic Clostridia: Clostridium perfringens Type A and Clostridium difficile	551	(12)
Bruce A. McClane
David M. Lyerly
J. Scott Moncrief
Tracy D. Wilkins
Histotoxic Clostridia	563	(10)
Dennis L. Stevens
Julian I. Rood
ACTINOMYCETALES
Corynebacterium diphtheriae: Iron-Mediated Activation of DtxR and Regulation of Diphtheria Toxin Expression	573	(10)
John F. Love
John R. Murphy
Actinomyces: Surface Macromolecules and Bacteria-Host Interactions	583	(11)
Maria K. Yeung
The Pathogenesis of Nocardia	594	(13)
Blaine L. Beaman
SECTION VI ANTIBIOTIC AND HEAVY METAL RESISTANCE MECHANISMS	607	(104)
Richard P. Novick
Mechanisms of Resistance to β-Lactam Antibiotics	609	(12)
Douglas S. Kernodle
Resistance to Glycopeptides in Gram-Positive Pathogens	621	(14)
Henry S. Fraimow
Patrice Courvalin
Aminoglycoside Resistance in Gram-Positive Bacteria	635	(12)
Karen J. Shaw
Gerard D. Wright
Mechanisms of Resistance to Heavy Metals and Quaternary Amines	647	(13)
Simon Silver
Richard Novick
Amit Gupta
Tetracycline Resistance in Gram-Positive Bacteria	660	(18)
Laura M. McMurry
Stuart B. Levy
Chloramphenicol Resistance	678	(7)
Iain A. Murray
Mechanisms of Fluoroquinolone Resistance	685	(9)
David C. Hooper
Resistance to the Macrolide-Lincosamide-Streptogramin Antibiotics	694	(17)
Bernard Weisblum
Appendix: Internet Addresses	711	(4)
Index	715