The Handbook of Alzheimer's Disease and Other Dementias

by Budson, Andrew E.; Kowall, Neil W.

• ISBN13: 9781405168281
• ISBN10: 1405168285
• Edition: 1st
• Format: Hardcover
• Copyright: 2011-11-07
• Publisher: Wiley-Blackwell

Summary

This is a broad-ranging review of the current research on Alzheimer?s disease and other dementias from both basic neuroscience and clinical perspectives. It provides scientists and medical professionals with an extensive introduction and an up-to-date review of cutting-edge scientific advances in a single volume. It will be an essential tool for physicians and medical students, psychologists, scientists, and allied health professionals including nurses, social workers, and therapists.?

Author Biography

Neil W. Kowall graduated with his MD from the University of British Columbia in 1979. He received postgraduate training in Internal Medicine at the Beth Israel Deaconess followed by a Neurology residency at Massachusetts General Hospital. After completion of his clinical training he completed a postdoctoral research fellowship and was appointed Assistant Professor of Neurology at Massachusetts General Hospital and Harvard Medical School . He moved to the Bedford VA Medical Center in 1992 where he is now Director of the New England Geriatrics Research Education and Clinical Center. He is a Professor of Neurology and Pathology at Boston University School of Medicine and directs the NIH-funded Boston University Alzheimer’s Disease Center. His major research interests are human neuroanatomy and neuropathology and animal models of neurodegenerative disease. NIH, VA and private foundations support his research. He has published over 100 original peer-reviewed manuscripts. Dr. Kowall has received various awards, including the following: two Medical Research Council Studentship awards, the Russel Prize in Anatomy, the Hamber Prize in Medicine, the Bristol Medical Prize in Pharmacology, the Merck Scholarship in Medical Therapeutics, the Mead Prize in Pediatrics, the FIRST Award (R29) from National Institute of Neurological Disorders and Stroke, the Moore Award for Best Paper on Clinicopathological Correlation from the American Association of Neuropathologists, two Director's Special Quality Awards/Commendations from the Bedford VAMC, and the Zenith Award from the Alzheimer's Association.

Andrew E. Budson (MD from Harvard Medical School) is Associate Professor of Neurology at Boston University's School of Medicine. He is also the Director of Cognitive Neuroscience Research at Boston University's Alzheimer's Center. He is a member of the Cognitive Neuroscience Society and American Academy of Neurology. He is on the editorial boards of several journals such as "Neuropsychology," "Cognitive Neuroscience," and "Neurobiology of Aging." He is a frequent invited speaker on Alzheimer's and cognitive disorders. His research uses the techniques of experimental psychology and cognitive neuroscience to understand how memory breaks down in patients with Alzheimer’s disease.

Table of Contents

Contributors	p. ix
Foreword	p. xii
Preface	p. xv
Common Dementias	p. 1
Alzheimer's Disease	p. 3
Vascular Dementia	p. 92
Dementia with Lewy Bodies	p. 131
Frontotemporal Dementia	p. 145
Other Dementias	p. 179
Pathogenesis and Disease Mechanisms	p. 195
Genetic Risk Factors for Dementia	p. 197
The Neuropathology of the Dementing Disorders	p. 235
Amyloid Beta Peptide and the Amyloid Cascade Hypothesis	p. 262
Other Mechanisms of Neurodegeneration	p. 277
Rational Therapeutics for Alzheimer's Disease and Other Dementias	p. 301
Cognitive and Behavioral Dysfunction	p. 313
Memory Dysfunction in Dementia	p. 135
Language Processing in Dementia	p. 336
Executive Functioning	p. 369
Emotion and Behavior in Alzheimer's Disease and Other Dementias	p. 416
Visuospatial Function in Alzheimer's Disease and Related Disorders	p. 457
Sleep and Orcadian Rhythms in Dementia	p. 483
Neuroimaging in Dementia	p. 505
Glimpses of the Living Brain with Alzheimer's Disease	p. 507
Functional MRI in Alzheimer's Disease and Other Dementias	p. 535
Molecular Neuroimaging of the Dementias	p. 557
Using EEG and MEG to Understand Brain Physiology in Alzheimer's Disease and Related Dementias	p. 575
Index	p. 604
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