Handbook of Animal Lectins Properties and Biomedical Applications

by Kilpatrick, David C.

• ISBN13: 9780471899815
• ISBN10: 047189981X
• Edition: 1st
• Format: Hardcover
• Copyright: 2000-11-08
• Publisher: WILEY

Summary

This comprehensive yet concise guide to animal lectins, covers all sources from unicellular protozoa and slime moulds through invertebrates to mammals and birds, and provides essential information to the widest possible readership. The last few years have seen an explosion of interest and research in animal lectins, and this book, which is divided into two parts, provides a compendium of galectins, collectins, selectins, pentraxins and other carbohydrate-binding proteins from throughout the animal kingdom. The first part introduces animal lectins on both phylogenetic and structural bases and outlines their key biomedical applications. The second, and major part, is a quick reference alphabetical directory listing around 170 lectins. Each lectin entry provides, where known, details of its: Isolation Structure Biological activities Tissue and/or subcellular distribution Possible functions Applications A bibliography for each lectin is also included and useful appendices list lectins according to their sugar specificity, characterised lectins of human origin by tissue source and commercial suppliers of animal lectins. This superb book is aimed at basic scientists and clinicians alike, and will be invaluable to both established research workers and newcomers to this area. It will be of particular interest to biochemists, cell biologists, immunologists, oncologists, pharmacologists, medical practitioners and students of medical and biological sciences.

Author Biography

David C. Kilpatrick is the author of Handbook of Animal Lectins: Properties and Biomedical Applications, published by Wiley.

Table of Contents

Preface	vii
Abbreviations	ix
Safety Notice	xi
Introduction to Animal Lectins	1	(10)
Definition of a lectin	1	(2)
Historical overview of animal lectins	3	(2)
Comparison of plant and animal lectins	5	(2)
Outline of this book	7	(4)
Invertebrate Lectins	11	(20)
Lectins from slime moulds, protozoa and sponges	11	(4)
Mollusc lectins	15	(1)
Annelid lectins	16	(1)
Arthropod lectins	17	(4)
Echinoderm lectins	21	(1)
Protochordate (tunicate) lectins	22	(9)
Vertebrate Lectins	31	(28)
S-type (galectins)	31	(4)
C-type (general)	35	(1)
C-type (hyalectans)	36	(1)
C-type (collectins)	36	(6)
C-type (selectins)	42	(2)
C-type (membrane receptors)	44	(2)
Pentraxins	46	(1)
I-type lectins	47	(1)
P-type lectins	48	(1)
Ficolins	48	(1)
Cytokine lectins	49	(10)
Biomedical Applications of Animal Lectins	59	(20)
Blood grouping reagents	59	(1)
Mitogenic agents	60	(2)
Lectins and haemostasis	62	(1)
Lectins and reproduction	63	(1)
Lectins and immunity	64	(2)
Lectins and cancer	66	(3)
Endogenous lectins as drugs and drug targets	69	(10)
Alphabetical Directory of Animal Lectins	79	(378)
Appendix A: Classification of lectins according to sugar specificity	457	(5)
Appendix B: Lectins of human origin by tissue source	462	(2)
Appendix C: Commercial suppliers of animal lectins	464	(2)
Index	466