Handbook of Biodegradable Polymers Isolation, Synthesis, Characterization and Applications

by Lendlein, Andreas; Sisson, Adam

• ISBN13: 9783527324415
• ISBN10: 3527324410
• Edition: 1st
• Format: Hardcover
• Copyright: 2011-08-15
• Publisher: Wiley-VCH

Summary

A comprehensive overview of the synthesis of biodegradable polymers, covering everything from synthesis, isolation, and degradation mechanisms while also introducing useful applications, such as drug delivery systems and regenerative medicine. An introductory section covers such fundamentals as basic chemical reactions during degradation, the complexity of biological environments and experimental methods for monitoring degradation processes. The result is a reliable reference source for those wanting to learn more about this important class of polymer materials, as well as scientists in the field seeking a deeper insight.

Author Biography

Andreas Lendlein is Director of the Institute of Polymer Research at Helmholtz-Zentrum Geesthacht in Teltow, Germany, and serves on the Board of Directors of the Berlin-Brandenburg Center for Regenerative Therapies, Berlin. He is Professor for Materials in Life Sciences
at University of Potsdam and Professor in Chemistry at the Freie Universit?t Berlin as well as member of the medical faculty of Charit? University Medicine Berlin. His research interests in macromolecular chemistry and material science are polymer-based biomaterials with special emphasis given to multifunctional materials, stimuli-sensitive polymers, especially shape-memory polymers, and biomimetic polymers. Furthermore, he explores potential applications of such biomaterials in biofunctional implants, controlled drug delivery systems, and regenerative therapies. He completed his habilitation in Macromolecular Chemistry in 2002 at the RWTH Aachen University, worked as a visiting scientist at the Massachusetts Institute of Technology, and received his doctoral degree in Materials Science from Swiss Federal Institute of Technology (ETH) in Z?rich in 1996. Andreas Lendlein received more than 20 awards for his scientific work, and his achievements as an entrepreneur including the BioFUTURE Award in 1998, the 2000 Hermann-Schnell Award and the World Technology Network Award in the category Health & Medicine in 2005. He has published more than 220 papers in journals and books, and is an inventor of more than 250 published patents and patent applications.

Adam Sisson received his PhD in Supramolecular Chemistry in 2005 under the guidance of Professor Anthony Davis at the University of Bristol, UK. Following this, he moved into the group of Professor Stefan Matile at the University of Geneva, Switzerland, to conduct postdoctoral
research in self-assembling nanomaterials. In 2007 he embarked upon research into polymeric nanogels as an Alexander von Humboldt Stiftung sponsored research fellow with Professor Rainer Haag at the Free University of Berlin, Germany. Since 2010 he is leading a Junior research group "Cell and Tissue Specific Materials" at the Berlin-Brandenburg Center for Regenerative Therapies, Helmholtz-Zentrum Geesthacht in Teltow, Germany. His research interests focus on studying and manipulating the interactions of synthetic materials with various
biological moieties in a range of applications.

Table of Contents

Preface

Polyesters

Biotechnologically Produced Biodegradable Polyesters

Polyanhydrides

Poly(ortho esters)

Biodegradable Polymers Composed of Naturally Occurring AlphaâÇôAmino Acids

Biodegradable Polyurethanes and Poly(ester aminde)s

Carbohydrates

Biodegradable ShapeâÇôMemory Polymers

Biodegradable Elastic Hydrogels for Tissue Expander Application

Biodegradable Dendrimers and Dendritic Polymers

Analytical Methods for Monitoring Biodegradation Processes of Environmentally Degradable Polymers

Modelling and Simulation of Microbial Depolymerization Processes of Xenobiotic Polymers

Regenerative Medicine: Reconstruction of Tracheal and Pharyngeal Mucosal Defects in Head and Neck Surgery

Biodegradable Polymers as Scaffolds for Tissue Engieering

Drug Delivery Systems

Oxobiodegradable Polymers: Present Status and Future Perspectives

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