Handbook of Probiotics and Prebiotics, 2nd Edition

by Yuan Kun Lee (National University of Singapore ; ); Seppo Salminen (Univ. of Turku, Finland)

• ISBN13: 9780470432617
• ISBN10: 0470432616
• Format: eBook
• Copyright: 2009-02-01
• Publisher: Wiley-Interscience

Summary

Since the publication of the first edition in 1999, the science of probiotics and prebiotics has matured greatly and garnered more interest. The first handbook on the market, Handbook of Probiotics and Prebiotics: Second Edition updates the data in its predecessor, and it also includes material topics not previously discussed in the first edition, including methods protocols, cell line and animal models, and coverage of prebiotics. The editors supplement their expertise by bringing in international experts to contribute chapters. This second edition brings together the information needed for the successful development of a pro- or prebiotic product from laboratory to market.

Table of Contents

Probiotics

Probiotic microorganisms

Definition

Screening, identification and characterization of Lactobacillus and Bifidobacillus strains

Detection and enumeration of gastrointestinal microorganisms

Enteric microbial community profiling in gastrointestinal tract by Terminal-Restriction Fragment Length Polymorphism (T-RFLP)

Effective dosage for probiotic effects

Incorporating probiotics into foods

Safety of probiotic microorganisms

Legal status and regulatory issues

Selection and maintenance of probiotic microorganisms

Isolation of probiotic microorganisms

Selection of probiotic mircroorganisms

Maintenance of Probiotic Microorganisms

Genetic modification of probiotic microorganisms

Mutants obtained from probiotic microorganisms by random mutagenesis

Plasmids

Vectors for Lactobacilli and Bifidobacteria

Genetic recombination

Role of probiotics in health and diseases

Cell line models in research

Laboratory animal models in research

Effects on human health and diseases

Effects on farm animals

Mechanisms of probiotics

Adhesion to intestinal mucus & epithelium by probiotics

Combined probiotics and pathogen adhesion and aggregation

Production of antimicrobial substances

Immune effects of probiotic bacteria

Alteration of microecology in human intestine

Commercially available human probiotic microorganisms

Lactobacillus acidophilus, LA-5?

Lactobacillus acidophilus NCDO1748

Lactobacillus acidophilus NFCM

Lactobacillus casei Shirota

Lactobacillus gasseri OLL2716 (LG21)

Lactobacillus paracasei ssp paracasei, F19“

Lactobacillus paracasei ssp paracasei, L. CASEI 431“

Lactobacillus rhamnosus GG, LGG“

Lactobacillus rhamnosus, GR-1“ and Lactobacillus reuteri , RC- 14“

Lactobacillus rhamnosus HN001 and

LGG“MAX, a multispecies probiotic combination

Bifidobacterium animalis ssp. lactis, BB-12“

Bifidobacterium breve strain Yakult

Bifidobacterium longum BB536

Bifidobacterium longum strains BL46 and BL2C - Probiotics for adults and ageing consumers

Prebiotics

Prebiotics

The prebiotic concept

A brief history of prebiotics

Advantages and disadvantages of the prebiotic strategy

Types of prebiotics

Production of prebiotics

Prebiotic mechanisms

Modulating the intestinal microbiota in infants

Modulating the intestinal microbiota in adults

Modifying the intestinal microbiota in the elderly

Health effects and applications of prebiotics

Functional foods for animals

Safety of prebiotics

Regulation of prebiotics

Conclusion

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