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9781405145510

Handbook of Veterinary Clinical Research

by ;
  • ISBN13:

    9781405145510

  • ISBN10:

    140514551X

  • Edition: 1st
  • Format: Paperback
  • Copyright: 2008-01-03
  • Publisher: Wiley-Blackwell
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Supplemental Materials

What is included with this book?

Summary

This is the first accessible reference on carrying out veterinary clinical research. It is designed for veterinary clinicians, students and researchers who need to learn about research methodology. It covers all the core research methods as well as detailing aspects specific to research in veterinary medicine. Special attention is given to ethical and legal issues, how to maximise the power of studies when faced with small numbers of patients, and how to go about research with few obvious resources to hand.

Author Biography

Dr Mark Holmes is a senior lecturer in preventive veterinary medicine, Chairman of the Farm Animal Epidemiology and Informatics Unit, and director of the Outreach Program of the Cambridge Infectious Diseases Consortium, at the University of Cambridge.
Dr Peter Cockcroft is Programme Director of Cambridge Expert Vets, an independent veterinary education, training and support business. He was previously a senior lecturer in farm animal medicine at the University of Cambridge for 11 years.

Table of Contents

Foreword
Introduction
What Is Veterinary Clinical Research?
What Is The 'Scientific Method'?
Errors And Truth
Why Do We Perform Veterinary Clinical Research?
Research From Practice.References
Establishing The Hypothesis
What Is The Question?
What Are The Characteristics Of A Good Research Question?
Selecting The Research Questions
The Hypothesis
The Question Doesn't Translate Into A Hypothesis
Initial Study Design
Problems With The Research Question And Study Design.Further Reading.Mcqs.Answers To Mcqs
Sampling, Subject Selection Criteria And Recruitment
Introduction
Surveys
Observational Clinical Studies And Clinical Trials
The Calculation Of Sample Size
Summary
Reference
Further Reading
Mcqs
Answers To Mcqs
Variables
Introduction
Types Of Variable
Measurement Scales
Precision And Accuracy
Summary
Further Reading
Mcqs
Answers To Mcqs
Introducing Statistics: Preparing To Make A Sample Size Estimation
Introduction
Statistical Principles
Testing For Statistical Significance
Other Statistical Tests And Choosing The Appropriate Statistical Test
Reference
Further Reading
Mcqs
Answers To Mcqs
How Many Animals/Patients Are Needed? Estimating The Sample Size
Introduction
Producing The Sample Size Estimate
Sample Size Required Per Group For The Comparison Of Two Means
Sample Size Required Per Group For The Comparison Of Multiple Means
Sample Size Required Per Group For The Comparison Of Two Proportions
Sample Size Techniques For Analytic Studies And Experiments
Further Considerations When Estimating Sample Size
References
Further Reading
Mcqs
Answers To Mcqs
Tables Estimating Sample Size Group For Comparing Two Proportions
Tables For Estimating The Sample Sizes When Comparing The Means From Two Groups
Tables For Estimating The Sample Size To Obtain The Value Of A Proportion
Table For Estimating A Sample Size To Obtain A Value For A Continuous Variable With A Particular Confidence Width
Tables For Estimating Sample Sizes For Studies Determining If Correlation Coefficients Differ From Zero
Observational Studies: Cohort Studies
Introduction
Cohort Studies
Prospective Cohort Studies
Retrospective Cohort Studies
Combined Prospective And Retrospective Survival Cohort Studies Across Time Andplace
Nested Case-Control And Case Cohort Studies
Multiple-Cohort Studies
Planning A Cohort Study
Cohort Studies And Prognosis
Summary
References
Further Reading
Mcqs
Answers To Mcqs
Cross-Sectional And Case-Control Studies
Introduction
Cross-Sectional Studies (Prevalence Studies)
Case-Control (Retrospective) Studies
Clinical Questions, Evidence And Experimental Design
Summary
References
Further Reading
Mcqs
Answers To Mcqs
Clinical Randomized Controlled Trials
Introduction
Randomized Controlled Trials
Cross-Over Designs
Factorial Design Trials
Features Of Randomized Clinical Trials
Poorly Controlled Or Uncontrolled Trials
Protocols
Summary
References
Further Reading
Mcqs.Answers To Mcqs
Studies On Diagnostic Tests
Introduction
Measuring The Specificity, Sensitivity And Prevalence
Tests With Continuous Measures
Studies That Compare Two Tests To Find Out Which Is Better
Prognostic Tests.10.6 Studies Of Test Reproducibility (Precision)
Studies On The Impact Of A Test On Patient Outcomes
Studies On
Table of Contents provided by Publisher. All Rights Reserved.

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