Head and Neck Cancer

by Harrison, Louis B.; Sessions, Roy B., M.D.; Hong, Waun Ki; Harrison, Louis B.

• ISBN13: 9780781733694
• ISBN10: 0781733693
• Edition: 2nd
• Format: Hardcover
• Copyright: 2003-10-01
• Publisher: LIPPINCOTT WILLIAMS & WILKINS

Summary

The focus of this text is the two-part approach that any physician treating head and neck cancer patients must follow: maximize the chance for a cure while maintaining a strong emphasis on quality of life. Coverage begins with reviews of the molecular biology and other basic science aspects of these cancers. The second section presents general principles of patient management, including physical examination, diagnostic imaging, head and neck pathology, dental oncology and maxillofacial prosthetics, nutritional management of the patient with head and neck cancer, head and neck oncologic nursing, reconstructive surgery, quality of life and psychiatric issues, and rehabilitation of speech, voice, and swallowing functions after cancer therapy. The third and major section offers detailed guidelines for surgical and non-surgical management of cancers at specific anatomic sites. The concluding section explores future directions in head and neck oncology, including radiation therapy, chemotherapy, gene and biological therapy, ethical considerations, outcomes research, and cost analysis. More than 1,600 illustrations complement the text. The Second Edition integrates a focus on technique into each site-specific chapter.

Table of Contents

Contributing Authors	xi
Preface	xix
Part I. General Principles of Management of Head and Neck Cancer
1. Physical Examination of the Head and Neck	3	(8)
Douglas K. Frank and Roy B. Sessions
2. General Principles of Head and Neck Pathology	11	(38)
Bruce M. Wenig and Jean-Marc Cohen
3. Prognostic Factors in Patients with Head and Neck Cancer	49	(25)
Benjamin D. Smith and Bruce G. Haffly
4. General Principles of Head and Neck Radiology	74	(31)
Bernard B. O'Malley and Suresh K. Mukherji
5. Intensity Modulated Radiotherapy of Head and Neck Cancer	105	(10)
Avraham Eisbruch
6. Dental Oncology and Maxillofacial Prosthetics	115	(15)
Jack W. Martin, Mark S. Chambers, and James C. Lemon
7. Nutritional Management of Patients with Head and Neck Cancer	130	(6)
Michael H. Torosian and John A. Ridge
8. Symptom Management and Supportive Care for Head and Neck Cancer Patients	136	(14)
Elise Carper, Stewart B. Fleishman, and Marlene McGuire
9. General Principles of Reconstructive Surgery for Head and Neck Cancer Patient	150	(15)
Mark D. DeLacure
10. Quality-of-Life Issues in Patients with Head and Neck Cancer	165	(13)
Russell K. Portenoy and Kevin T. Sperber
11. General Principles of Rehabilitation of Speech, Voice, and Swallowing Function After Treatment of Head and Neck Cancer	178	(12)
Susan D. Miller and Lucian Sulica
12. Ethical considerations in Head and Neck Cancer	190	(13)
Edmund D. Pellegrino
Part II. Site-Specific Principles of Management of Head and Neck Cancer
13. Surgical Management of Cervical Lymph Nodes	203	(25)
Jesus E. Medina and John R. Houck, Jr.
14. Radiation Therapy and Chemotherapy Management of Cervial Lymph Nodes	228	(17)
Harry Quon and Louis B. Harrison
15. Metastatic Cancer to the Neck from an Unknown Primary Site	245	(21)
Bruce J. Davidson and K. William Harter
16. Cancer of the Oral Cavity	266	(40)
Jatin P. Shah and Michael J. Zelefsky
17. Cancer of the Oropharynx	306	(46)
Kenneth S. Hu, Louis B. Harrison, Bruce Culliney, Adam P. Dicker, and Roy B. Sessions
18. Early Stage Cancer of the Larynx	352	(29)
William M. Mendenhall, Lucian Sulica, and Roy B. Sessions
19. Advanced Stage Cancer of the Larynx	381	(23)
Gary L. Clayman, Douglas K. Frank, Adam S. Garden, and Merrill S. Kies
20. Cancer of the Hypopharynx and Cervical Esophagus	404	(51)
David G. Pfister, Kenneth S. Hu, and Jean-Louis Lefebvre
21. Cancer of the Nasal Vestibule, Nasal Cavity, and Paranasal Sinus: Surgical Management	455	(25)
Peter D. Costantino, Mark R. Murphy, and Jason A. Moche
22. Cancer of the Nasal Vestibule, Nasal Cavity, and Paranasal Sinus: Radiation Therapy and Chemotherapy Management	480	(49)
James T. Parsons and Merrill S. Kies
23. Cancer of the Nasopharynx	529	(31)
Lester J. Peters, Danny Rischip, June Corry, and Paul M. Harari
24. Basal and Squamous Cell Skin Cancers of the Skin of the Head and Neck	560	(38)
Randal S. Weber, Geoffrey L. Robb, and Adam S. Garden
25. Melanoma of the Head and Neck	598	(22)
Ann M. Gillenwater and Robert M. Byers
26. Management of Malignant Salivary Gland Tumors	620	(32)
David W. Eisele and Lawrence R. Kleinberg
27. Cancers Involving the Skull Base and Temporal Bone	652	(26)
Ivo P. Janecka, Silloo B. Kapadia, Anthony A. Mancuso, Sanjay Prasad, David A. Moffat, and Julian J. Pribaz
28. Paragangliomas of the Head and Neck	678	(36)
Mark S. Persky, Kenneth S. Hu, and Alejandro Berenstein
29. Cancer of the Thyroid Gland	714	(72)
Roy B. Sessions and Kenneth D. Burman
30. Soft Tissue and Bone Sarcomas of the Head and Neck	786	(38)
Brian O'Sullivan, Nathalie Audet, Charles N. Catton, and Patrick J. Gullave
31. Cancer of the Orbit: Surgical Management	824	(27)
Gregg S. Gayre, Christopher M. DeBacker, and Jonathan J. Dutton
32. Cancer of the Orbit and Ocular Structures: Radiation Therapy and Management	851	(18)
Jorge E. Freire, Luther W. Brady, Lydia T. Komarnicky, Jerry A. Shields, and Carol L. Shields
33. Unusual Tumors of the Head and Neck	869	(30)
Ashok R. Shaka and John F. Carew
34. Lymphomas of the Head and Neck	899	(20)
M. Alma Rodriguez and Ali W Bseiso
35. Systemic Therapy for Recurrent and Metastatic Diseases	919	(10)
Charles Lu and Merrill S. Kies
Part III. Basic Science and Pathology of Head and Neck Cancer
36. Molecular Biology of Head and Neck Cancer	929	(8)
Joseph A. Califano III and David Sidransky
37. Molecular Epidemiology and Genetic Predisposition for Head and Neck Cancer	937	(11)
Margaret R. Spitz, Erich M. Sturgis, and Qingyi Wei
38. Invasion and Metastases in Head and Neck Cancer	948	(25)
F. Christopher Holsinger, Janet I. Lee, Eric J. Lentsch, and Jeffrey N. Myers
39. Human Papillomavirus and Head and Neck Cancer	973	(12)
Bettie M. Steinberg
40. Chemoprevention of Head and Neck Cancer	985	(16)
Vassiliki A. Papadimitrakopoulou, Dong M. Shin, and Waun Ki Hong
41. Molecular Targeting of the Epidermal Growth Factor Receptor in Head and Neck Cancer	1001	(17)
Paul M. Harari, Shyh-Min Huang, Roy S. Herbst, and Harry Quon
42. Gene Replacement Therapy	1018	(11)
Randall L. Breau and Gary L. Clayman
Appendix: Imaging Considerations for Radiation Therapy Treatment Planning	1029	(20)
Louis B. Harrison and Bernard B. O'Malley
Subject Index	1049