Head Trauma Basic, Preclinical, and Clinical Directions

by Miller, Leonard P.; Hayes, Ronald L.; Newcomb, Jennifer K.

• ISBN13: 9780471360155
• ISBN10: 0471360155
• Edition: 1st
• Format: Hardcover
• Copyright: 2001-04-06
• Publisher: Wiley-Liss

Summary

With this book, neurosurgeons, neurologists, neurophysiologists, and neuroscientists now have a definitive reference on the subject of head trauma.

Author Biography

Leonard P. Miller is the author of Head Trauma: Basic, Preclinical, and Clinical Directions, published by Wiley.

Table of Contents

Foreword	xi
Lawrence F. Marshall
Preface	xiii
Contributors	xv
I. BASIC SCIENCE: OVERVIEW
Overview of Basic Mechanisms Underlying Neuropathological Consequences of Head Trauma	3	(34)
Philipp M. Lezlinger
Kathryn E. Saatman
Ramesh Raghupathi
Tracy K. Mclntosh
In Vitro Models of Traumatic Brain Injury	37	(28)
Brian R. Pike
Contemporary in Vivo Models of Brain Trauma and a Comparison of Injury Responses	65	(22)
Anthony E. Kline
C. Edward Dixon
II. PRECLINICAL STUDIES
The Role of Glutamate Receptors in the Pathophysiology of Traumatic Brain Injury	87	(28)
Meredith D. Temple
Deirdre M. O'Leary
Alan Faden
Cholinergic Receptors in Head Trauma	115	(26)
Bruce G. Lyeth
Adenosine Receptor Activation in Traumatic Brain Injury	141	(24)
Patrick Kochanek
Leonard P. Miller
Growth Factors	165	(24)
Seth P. Finklestein
Androniki Plomaritoglou
The Inflammatory Response as a Therapeutic Target in Traumatic Brain Injury	189	(14)
Patrick M. Kochanek
Michael J. Whalen
Timothy M. Carlos
Robert S. B. Clark
C. Edward Dixon
Steven DeKosky
Donald W. Marion
Contribution of Ionic Alterations to Metabolic Dysfunction Following Traumatic Brain Injury	203	(16)
Amir Samii
Amy H. Moore
Christopher C. Giza
David A. Hovda
Contribution of Calpains and Caspases to Cell Death Following Traumatic Brain Injury	219	(20)
R. L. Hayes
J. K. Newcomb
B. R. Pike
S. M. Deford
Apoptosis and DNA Damage	239	(18)
Ramesh Raghupathi
Mitochondrial Dysfunction Following Traumatic Brain Injury	257	(24)
Y. Xiong
P. L. Peterson
C. P. Lee
Traumatic Axonal Injury	281	(22)
John T. Povlishock
James R. Stone
Vascular Aspects of Severe Head Injury	303	(24)
Marike Zwienenberg
J. Paul Muizelaar
III. CLINICAL DIRECTIONS
Epidemiology and Economics of Head Trauma	327	(22)
D. J. Thurman
Clinical Presentation and Neuropsychological Sequelae of Traumatic Brain Injury	349	(22)
Sharon A. Brown
Harvey S. Levin
The American Brain Injury Consortium	371	(14)
Tony Marmarou
Guidelines for Medical and Surgical Management in Head Trauma Patients in the United States and Europe	385	(32)
Domenico d'Avella
Giustino Tomei
Clinical Trials in Head Injury: United States	417	(16)
Paul Muizelaar
Leonard P. Miller
Clinical Trials in Head Injury: Europe	433	(28)
A. I. R. Maas
Clinical Trials in Head Injury: Asia	461	(20)
Sadahiro Maejima
Yoichi Katayama
Appendix	481	(4)
Index	485